Results 81 to 90 of about 100,181 (178)
BMC Plant Biology, 2019 Background Heavy metal toxicity has become a major threat to sustainable crop production worldwide. Thus, considerable interest has been placed on deciphering the mechanisms that allow plants to combat heavy metal stress.
Weixuan Cong +14 more
doaj +1 more source
Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. [PDF]
, 2017 BACKGROUND: Maintenance of cell fate determination requires the Polycomb group for repression; the trithorax group for gene activation; and the enhancer of trithorax and Polycomb (ETP) group for both repression and activation.
Brock, Hugh W +4 more
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Journal of Ovarian ResearchObjective Mechanism underlying the etiology of polycystic ovary syndrome (PCOS) is still debatable. Present study explores the link between iron-mediated ferroptosis and PCOS.
Nighat Hayat +4 more
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Entanglement of Genetics and Epigenetics in Parkinson’s Disease
Frontiers in Neuroscience, 2019 Parkinson disease (PD) is a common neurodegenerative disorder that progresses with age, with an increasing number of symptoms. Some of the efforts to understand PD progression have been focusing on the regulation of epigenetic mechanisms, that generally ...
H. J. van Heesbeen, Marten P. Smidt
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, 2013 Cover image by artist Syd Moen; Benefactor News: Smithville fundraiser supports GSBS fellow; New endowment to support MD/PhD Program; Coming full circle: developing and promoting a Core Curriculum; Celebrating 50 Years of Excellence: GSBS Alumni All ...
Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston/M.D. Anderson Cancer Center
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A MeA Tac1 neural circuit mediates anxiety-like behaviors in mice
EMBO ReportsAnxiety is an emotion characterized by worried thoughts and feelings of unease, often accompanied by physical symptoms such as sweating and dizziness. Unlike other negative emotions, the neural circuits underlying anxiety are not well understood. Here we
Yao Wang +10 more
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Functional Implications of DNA Methylation in Adipose Biology. [PDF]
, 2019 The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
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Epigenetic Chromatin Silencing: Bistability and Front Propagation
, 2007 The role of post-translational modification of histones in eukaryotic gene regulation is well recognized. Epigenetic silencing of genes via heritable chromatin modifications plays a major role in cell fate specification in higher organisms.
Alberts B +13 more
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Understanding epigenetics in health and human diseases – An overview
Journal of Integrative Medicine and ResearchEpigenetics, the study of heritable changes in gene expression without alterations to the DNA sequence, is crucial for the complex interplay of genetic and environmental factors influencing human health.
Avarna Agarwal, Prasanta Padhan
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How Can We Move Clinical Genomics Beyond the Hype? [PDF]
, 2011 Examines the debate over increased use of genetic testing, due in part to lax regulation, and its consequences: wasteful spending, patient harm, and health system challenges.
Michael L. Millenson
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