Results 11 to 20 of about 12,898 (182)

Equivalence of the GeneXpert System and GeneXpert Omni System for tuberculosis and rifampicin resistance detection

PLOS ONE, 2021
A laboratory validation study was conducted to assess the equivalence of Xpert MTB/RIF Ultra testing on the GeneXpert System and the GeneXpert Omni System (‘Omni’) for tuberculosis and rifampicin resistance. High concordance of the two devices was demonstrated for well-characterized clinical samples as well as control materials, with controls tested on
Sophia B. Georghiou, Riccardo Alagna, Daniela M. Cirillo, Sergio Carmona, Morten Ruhwald, Samuel G. Schumacher   +5 more
openaire   +4 more sources

Evaluation of the GeneXpert for Human Monkeypox Diagnosis [PDF]

The American Society of Tropical Medicine and Hygiene, 2017
Monkeypox virus (MPXV), a zoonotic orthopoxvirus (OPX), is endemic in the Democratic Republic of Congo (DRC). Currently, diagnostic assays for human monkeypox (MPX) focus on real-time quantitative polymerase chain reaction (PCR) assays, which are typically performed in sophisticated laboratory settings.
Li, Daniel, Wilkins, Kimberly, McCollum, Andrea M., Osadebe, Lynda, Kabamba, Joelle, Nguete, Beatrice, Likafi, Toutou, Balilo, Marcel Pie, Lushima, Robert Shongo, Malekani, Jean, Damon, Inger K., Vickery, Michael C. L., Pukuta, Elisabeth, Nkawa, Frida, Karhemere, Stomy, Tamfum, Jean-Jacques Muyembe, Okitolonda, Emile Wemakoy, Li, Yu, Reynolds, Mary G.   +18 more
openaire   +2 more sources

Contributions of GeneXpert^® to TB diagnosis in Myanmar

The International Journal of Tuberculosis and Lung Disease, 2022
BACKGROUND: Xpert® MTB/RIF, a rapid, molecular TB diagnostic assay, can detect Mycobacterium tuberculosis and rifampin resistance directly from clinical sputum samples in <2 h with high sensitivity and specificity. The added diagnostic value of Xpert over smear microscopy at a national level in Myanmar has not been previously reported.METHODS: We ...
Burger, Z, Aung, HT, Seifert, M, Mar, TT, Harris, V, Colman, RE, Rodwell, TC, Aung, ST   +7 more
openaire   +4 more sources

Role of GeneXpert or CBNAAT in Diagnosing Tuberculosis

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
About a quarter of the world's population is infected with tuberculosis (TB), with new infection occurring every second. The global burden, particularly with multidrug resistance, is also increasing simultaneously and has become a major health challenge.
Archana Garg, Lakshmi Agarwal, Rishab Mathur   +2 more
openaire   +2 more sources

GeneXpert for TB diagnosis: planned and purposeful implementation [PDF]

Global Health: Science and Practice, 2013
Xpert MTB/RIF es un avance importante para el diagnóstico de la TB, especialmente para la TB multirresistente (MDR) y la TB asociada al VIH. Pero las preocupaciones de implementación, incluidos los costos, los requisitos de soporte técnico y las exigentes demandas de proporcionar medicamentos de segunda línea contra la tuberculosis para casos ...
Amy S. Piatek, Maarten Van Cleeff, Heather Alexander, William Coggin, Manuela Rehr, Sanne van Kampen, Thomas M. Shinnick, YaDiul Mukadi   +7 more
openaire   +4 more sources

Evaluation of rapid diagnostic tests and assessment of risk factors in drug-resistant pulmonary tuberculosis

Journal of Family Medicine and Primary Care, 2020
Background: Early diagnosis and treatment of drug-resistant tuberculosis (TB) is crucial to halt the spread of drug resistance in the community. Aim: The aim of the study was to compare rapid diagnostic tests (GeneXpert and line probe assay, LPA) with ...
Vimal Kumar, Pankaj Jorwal, Manish Soneja, Sanjeev Sinha, Neeraj Nischal, Prayas Sethi, Saikat Mondal, Zia Abdullah, R M Pandey   +8 more
doaj   +1 more source

Assessment of Conventional and Molecular Methods in the Routine Management of Tuberculosis in a High Tuberculosis Burden Setting

Epidemiology and Health System Journal, 2023
Background and aims: India is a high-burden tuberculosis (TB) region and a drug-resistance hotspot. Despite numerous reports of pulmonary tuberculosis (PTB) cases, there needs to be more literature available on the importance of diagnostic methods in ...
Mehvash Haider
doaj   +1 more source

Sensitivitas dan Spesifisitas GeneXpert pada Sputum Pasien Suspek Tuberkulosis Paru

Jurnal Ilmu Kesehatan Indonesia, 2022
Latar Belakang: Indonesia menempati urutan kedua setelah India sebagai negara dengan penderita TB terbanyak. Waktu pemeriksaan yang lama menjadi faktor yang menghambat upaya penanggulangan TB.
Yasmin Nasywa, Netti Suharti, Yusticia Katar   +2 more
doaj   +1 more source

Discordance between GeneXpert assay and conventional drug-susceptibility testing in detecting rifampicin-resistant tuberculosis: A perspective of the line probe assay

International Journal of Mycobacteriology, 2016
Background: Early detection for tuberculosis (TB) and rifampicin-resistant TB (RRTB) is crucial for proper control of this disease. WHO recommended the use of the GeneXpert assay at district level to cover these two public health demands?
Ruqaya M Ali, Ahmed A Alsudani
doaj   +1 more source

Tuberculous osteomyelitis of proximal fibula: An unusual presentation of tuberculosis

Journal of Orthopedics, Traumatology and Rehabilitation, 2021
Tubercular involvement of the proximal fibula is very rare. We present a case of tuberculosis of proximal fibula in an immunocompetent young female. She was diagnosed clinically as a case of cellulitis.
Gunjar Jain, Asjad Mahmood
doaj   +1 more source