Results 241 to 250 of about 10,751,278 (348)
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Nature, 2007 E. Birney, J. Stamatoyannopoulos, A. Dutta, R. Guigó, T. Gingeras, E. Margulies, Z. Weng, M. Snyder, E. Dermitzakis, R. Thurman, Michael S. Kuehn, Christopher M. Taylor, Shane J. Neph, Christoph M. Koch, S. Asthana, A. Malhotra, I. Adzhubei, J. Greenbaum, R. Andrews, Paul Flicek, Patrick J Boyle, Hua Cao, N. Carter, Gayle K. Clelland, S. Davis, Nathan Day, P. Dhami, Shane C. Dillon, M. Dorschner, H. Fiegler, P. Giresi, J. Goldy, M. Hawrylycz, Andrew K. Haydock, R. Humbert, K. James, Brett E. Johnson, Ericka M. Johnson, Tristan Frum, Elizabeth R. Rosenzweig, N. Karnani, K. Lee, Gregory Lefebvre, P. Navas, Fidencio V. Neri, Stephen C. J. Parker, P. Sabo, R. Sandstrom, A. Shafer, D. Vetrie, M. Weaver, S. Wilcox, Man Yu, F. Collins, J. Dekker, J. Lieb, T. Tullius, G. Crawford, S. Sunyaev, W. S. Noble, I. Dunham, F. Denoeud, A. Reymond, P. Kapranov, J. Rozowsky, D. Zheng, R. Castelo, A. Frankish, J. Harrow, Srinka Ghosh, A. Sandelin, I. Hofacker, R. Baertsch, Damian Keefe, S. Dike, Jill Cheng, H. Hirsch, E. Sekinger, Julien Lagarde, J. F. Abril, Atif Shahab, Christoph Flamm, C. Fried, J. Hackermüller, Jana Hertel, Manja Lindemeyer, Kristin Missal, Andrea Tanzer, Stefan Washietl, J. Korbel, O. Emanuelsson, J. S. Pedersen, N. Holroyd, Ruth Taylor, D. Swarbreck, N. Matthews, M. Dickson, D. Thomas, M. Weirauch, J. Gilbert, J. Drenkow, I. Bell, X. Zhao, K. Srinivasan, W. Sung, H. Ooi, K. Chiu, S. Foissac, T. Alioto, M. Brent, L. Pachter, M. Tress, A. Valencia, S. Choo, C. Choo, C. Ucla, C. Manzano, Carine Wyss, E. Cheung, T. Clark, James B. Brown, M. Ganesh, Sandeep Patel, H. Tammana, Jacqueline Chrast, Charlotte N. Henrichsen, C. Kai, J. Kawai, Ugrappa Nagalakshmi, Jiaqian Wu, Zheng Lian, Jin Lian, P. Newburger, Xueqing Zhang, P. Bickel, J. Mattick, Piero Carninci, Y. Hayashizaki, S. Weissman, T. Hubbard, R. M. Myers, J. Rogers, P. Stadler, T. Lowe, Chia-Lin Wei, Y. Ruan, K. Struhl, M. Gerstein, S. Antonarakis, Yutao Fu, E. Green, Ulas Karaöz, A. Siepel, James Taylor, L. Liefer, K. Wetterstrand, P. Good, E. Feingold, M. Guyer, G. Cooper, G. Asimenos, Colin N. Dewey, Minmei Hou, S. Nikolaev, J. Montoya-Burgos, A. Löytynoja, S. Whelan, F. Pardi, Tim Massingham, Haiyan Huang, Na Zhang, I. Holmes, J. Mullikin, A. Ureta-Vidal, B. Paten, Michael R. Seringhaus, D. Church, K. Rosenbloom, W. Kent, Eric A. Stone, S. Batzoglou, N. Goldman, R. Hardison, D. Haussler, Webb Miller, A. Sidow, N. Trinklein, Zhengdong D. Zhang, Leah Barrera, R. Stuart, D. King, A. Ameur, Stefan Enroth, M. Bieda, Jonghwan Kim, A. Bhinge, N. Jiang, Jun Liu, Fei Yao, V. Vega, C. Lee, Patrick Ng, A. Yang, Z. Moqtaderi, Zhou Zhu, Xiaoqin Xu, S. Squazzo, M. Oberley, David Inman, Michael A. Singer, T. Richmond, Kyle J. Munn, Á. Rada-Iglesias, O. Wallerman, J. Komorowski, J. Fowler, Phillippe Couttet, Alexander W. Bruce, O. Dovey, P. Ellis, C. Langford, D. Nix, G. Euskirchen, S. Hartman, A. Urban, P. Kraus, Sara Van Calcar, Nathaniel D. Heintzman, Tae Hoon Kim, Kun Wang, Chunxu Qu, G. Hon, R. Luna, C. Glass, M. Rosenfeld, S. F. Aldred, S. Cooper, Anason S. Halees, J. M. Lin, H. Shulha, Xiaoling Zhang, Mousheng Xu, Jaafar N. Haidar, Yon-Jong Yu, V. Iyer, Roland Green, C. Wadelius, P. Farnham, B. Ren, R. Harte, A. Hinrichs, Heather Trumbower, H. Clawson, Jennifer Hillman-Jackson, A. Zweig, Kayla E. Smith, Archana Thakkapallayil, G. Barber, R. Kuhn, D. Karolchik, L. Armengol, C. Bird, P. D. de Bakker, Andrew D. Kern, N. López-Bigas, Joel D Martin, B. Stranger, A. Woodroffe, Eugene Davydov, A. Dimas, E. Eyras, Ingileif B. Hallgrímsdóttir, J. Huppert, M. Zody, G. Abecasis, X. Estivill, G. Bouffard, Xiaobin Guan, Nancy F. Hansen, J. Idol, V. Maduro, Baishali Maskeri, Jennifer C Mcdowell, Morgan Park, Pamela J. Thomas, Alice C. Young, R. Blakesley, D. Muzny, E. Sodergren, D. Wheeler, K. Worley, Huaiyang Jiang, G. Weinstock, R. Gibbs, T. Graves, R. Fulton, E. Mardis, R. Wilson, M. Clamp, James A. Cuff, S. Gnerre, D. Jaffe, Jean L. Chang, K. Lindblad-Toh, E. Lander, M. Koriabine, M. Nefedov, K. Osoegawa, Y. Yoshinaga, B. Zhu, P. D. de Jong +310 moresemanticscholar +1 more sourceMETTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu +15 morewiley +1 more sourceAdenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori +15 morewiley +1 more sourcePossible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak +2 morewiley +1 more source
