Results 51 to 60 of about 70 (69)
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Protozoan genomes: gene identification and annotation
International Journal for Parasitology, 2005The draft sequence of several complete protozoan genomes is now available and genome projects are ongoing for a number of other species. Different strategies are being implemented to identify and annotate protein coding and RNA genes in these genomes, as well as study their genomic architecture.
Elizabeth A. Worthey, Peter J. Myler
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Genomics, pathogenesis and control of infection with protozoan parasites
Trends in Parasitology, 2002Abstract The XXVIII Annual Meeting of Basic Research on Chagas Disease and XVII Annual Meeting of the Brazilian Society of Protozoology were held 5–7 November, 2001, in Caxambu, Minas Gerais, Brazil.
Ricardo T. Gazzinelli+2 more
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Integration of tools and resources for display and analysis of genomic data for protozoan parasites
International Journal for Parasitology, 2005Centralisation of tools for analysis of genomic data is paramount in ensuring that research is always carried out on the latest currently available data. As such, World Wide Web sites providing a range of online analyses and displays of data can play a crucial role in guaranteeing consistency of in silico work.
Martin Aslett+13 more
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PROTOGIM: a novel tool to search motifs and domains in hypothetical proteins of protozoan genomes
Parasitology Research, 2005Whole sequencing of protozoan trypanosomatid genomes revealed the presence of several predicted unknown genes coding for hypothetical proteins. Pairwise, alignment-based, computational methods available online are unable to identify the function of these sequences.
Igor Cestari+3 more
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Protozoan Genomes: Karyotype Analysis, Chromosome Structure, and Chromosome Specific Libraries
2003Protozoa represent a diverse group of single-celled eukaryotes, many of which have parasitic life styles, infecting hundreds of millions of people. Unique aspects of their biology relate to their distinct evolutionary position and their complex life cycles, frequently involving different hosts.
Van der Ploeg Lh+4 more
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Genomics and Genetic Manipulation of Protozoan Parasites Affecting Farm Animals
2017In this chapter we present a brief but state-of-the-art account of the genomics and current gene manipulation methods that can be used to improve our understanding of the genetics and the biology of an arbitrary group of 17 protozoan parasites responsible for diseases that affect animals worldwide, including babesiosis, toxoplasmosis, theileriosis ...
Heba F. Alzan+2 more
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Post genomic analysis of permeases from the amino acid/auxin family in protozoan parasites
Biochemical and Biophysical Research Communications, 2004The "amino acid/auxin permeases" is probably the most represented family of transporters in the Trypanosoma cruzi genome. Using a high-throughput searching routine and preliminary data from the T. cruzi genome project, more than 15,000 sequences were iteratively assembled into contigs, and 60 open reading frames corresponding to different putative ...
Renata Rosito Tonelli+8 more
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Molecular and Biochemical Parasitology, 1990
Cysteine protease gene fragments from three protozoan parasites Trypanosoma cruzi, Trypanosoma brucei, and Entamoeba histolytica were amplified by the polymerase chain reaction (PCR) from genomic DNA using degenerate oligonucleotide primers. The primers used for the amplification were designed based upon amino acid sequences flanking the active site ...
James H. McKerrow+4 more
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Cysteine protease gene fragments from three protozoan parasites Trypanosoma cruzi, Trypanosoma brucei, and Entamoeba histolytica were amplified by the polymerase chain reaction (PCR) from genomic DNA using degenerate oligonucleotide primers. The primers used for the amplification were designed based upon amino acid sequences flanking the active site ...
James H. McKerrow+4 more
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Many task computing for orthologous genes identification in protozoan genomes using Hydra
Concurrency and Computation: Practice and Experience, 2011SUMMARYOne of the main advantages of using a scientific workflow management system (SWfMS) is to orchestrate data flows among scientific activities and register provenance of the whole workflow execution. Nevertheless, the execution control of distributed activities in high performance computing environments by SWfMS presents challenges such as ...
Vanessa Braganholo+6 more
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2021
Due to highly repetitive genome sequences, short-read-based Trypanosoma cruzi genomes are extremely fragmented. Contiguous trypanosomatid genomes assemblies have resulted in the advent of third-generation sequencing technologies. Long reads span several to hundreds of kbps allowing to correct assemblies of repeated and low complexity DNA regions ...
Carlos Robello+5 more
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Due to highly repetitive genome sequences, short-read-based Trypanosoma cruzi genomes are extremely fragmented. Contiguous trypanosomatid genomes assemblies have resulted in the advent of third-generation sequencing technologies. Long reads span several to hundreds of kbps allowing to correct assemblies of repeated and low complexity DNA regions ...
Carlos Robello+5 more
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