Results 51 to 60 of about 1,052,313 (231)
Membrane-associated proteins in giardia lamblia [PDF]
, 2018 The manner in which membrane-associated proteins interact with the membrane defines their subcellular fate and function. This interaction relies on the characteristics of the proteins, their journey after synthesis, and their interaction with other ...
Feliziani, Constanza +2 more
core +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
Taming Parasites by Tailoring Them
Frontiers in Cellular and Infection Microbiology, 2017 The next-generation gene editing based on CRISPR (clustered regularly interspaced short palindromic repeats) has been successfully implemented in a wide range of organisms including some protozoan parasites.
Bingjian Ren, Nishith Gupta
doaj +1 more source
BMC Ecology, 2003 Background The rapid expansion in the availability of genome and DNA sequence information has opened up new possibilities for the development of methods for detecting free-living protozoa in environmental samples.
Hughes Jacqueline M +2 more
doaj +1 more source
Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
bioRxiv, 2020 The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in humans and other mammals, despite the development of potent host immune responses that constrain parasite numbers. The consistent, decades-long persistence of T.
Wei Wang +5 more
semanticscholar +1 more source
BMC Genomics, 2010 Background Chromatin in the nucleus of all eukaryotes is organized into a system of loops and domains. These loops remain fastened at their bases to the fundamental framework of the nucleus, the matrix or the scaffold.
Gautam Pennathur +5 more
doaj +1 more source
bioRxiv, 2021 Background The kinetoplastid protozoan Leishmania tropica mainly causes cutaneous leishmaniasis in humans in the Middle East, and relapse or treatment failure after treatment are common in this area. L.
Hedvig Glans +6 more
semanticscholar +1 more source
Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]
, 2019 Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña +5 more
core +2 more sources
Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major
Journal of Nucleic Acids, 2010 A wide variety of DNA lesions arise due to environmental agents, normal cellular metabolism, or intrinsic weaknesses in the chemical bonds of DNA. Diverse cellular mechanisms have evolved to maintain genome stability, including mechanisms to repair ...
Danielle Gomes Passos-Silva +5 more
doaj +1 more source
Microbial Cell Factories, 2021 Background Noroviruses are a major cause of epidemic and sporadic acute non-bacterial gastroenteritis worldwide. Unfortunately, the development of an effective norovirus vaccine has proven difficult and no prophylactic vaccine is currently available ...
Mirosława Panasiuk +9 more
doaj +1 more source