Results 11 to 20 of about 1,842,476 (313)
Alvira : comparative genomics of viral strains [PDF]
Bioinformatics, 2007 The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Fremez, Romain +7 more
core +8 more sources
Viral Genome Deep Classifier [PDF]
IEEE Access, 2019 The task of virus classification into subtypes is an important concern in many categorization studies, e.g., in virology or epidemiology. Therefore, the problem of virus subtyping has been a subject of considerable interest in the last decade.
Anna Fabijanska, Szymon Grabowski
doaj +2 more sources
Approaches to quantifying hepatitis B virus covalently closed circular DNA [PDF]
Clinical and Molecular Hepatology, 2022 Chronic hepatitis B is a major cause of liver disease worldwide and is currently incurable. Hepatitis B virus (HBV) covalently closed circular (ccc) DNA is a key form of the virus responsible for its persistence and is the transcriptional template for ...
Henrik Zhang, Thomas Tu
doaj +1 more source
Expansion of Viral Genomes with Viral Protein Genome Linked Copies
SSRN Electronic Journal, 2022 Virus protein-linked genome (VPg) proteins are required for replication. VPgs are duplicated in a subset of RNA viruses however their roles are not fully understood and the extent of viral genomes containing VPg copies has not been investigated in detail.
Reid, Warsaba +3 more
openaire +2 more sources
Informative Regions In Viral Genomes [PDF]
Viruses, 2021 Viruses, far from being just parasites affecting hosts’ fitness, are major players in any microbial ecosystem. In spite of their broad abundance, viruses, in particular bacteriophages, remain largely unknown since only about 20% of sequences obtained from viral community DNA surveys could be annotated by comparison with public databases.
Jaime Leonardo Moreno-Gallego +1 more
openaire +6 more sources
Viral component of the human genome [PDF]
Molecular Biology, 2017 Relationships between viruses and their human host are traditionally described from the point of view taking into consideration hosts as victims of viral aggression, which results in infectious diseases. However, these relations are in fact two-sided and involve modifications of both the virus and host genomes.
Blinov, V. M. +4 more
openaire +3 more sources
NCBI Viral Genomes Resource [PDF]
Nucleic Acids Research, 2014 Recent technological innovations have ignited an explosion in virus genome sequencing that promises to fundamentally alter our understanding of viral biology and profoundly impact public health policy. Yet, any potential benefits from the billowing cloud of next generation sequence data hinge upon well implemented reference resources that facilitate ...
J. Rodney Brister +3 more
openaire +2 more sources
The Role of the Stem-Loop A RNA Promoter in Flavivirus Replication
Viruses, 2021 An essential challenge in the lifecycle of RNA viruses is identifying and replicating the viral genome amongst all the RNAs present in the host cell cytoplasm. Yet, how the viral polymerase selectively recognizes and copies the viral RNA genome is poorly
Kyung H. Choi
doaj +1 more source
Genomics in Plant Viral Research
Viruses, 2022 Plant viruses constitute a large group of pathogens causing damaging diseases in many agricultural and horticultural crops around the world [...]
Solomon Maina, Brendan Rodoni
openaire +3 more sources
Intracellular sensing of viral genomes and viral evasion [PDF]
Experimental & Molecular Medicine, 2019 AbstractDuring viral infection, virus-derived cytosolic nucleic acids are recognized by host intracellular specific sensors. The efficacy of this recognition system is crucial for triggering innate host defenses, which then stimulate more specific adaptive immune responses against the virus.
Hyun-Cheol Lee +2 more
openaire +3 more sources