Results 41 to 50 of about 2,630,320 (343)

Subcellular distribution of the rAAV genome depends on genome structure

open access: yesScientific Reports, 2023
Many studies have been conducted on the transduction efficiency of recombinant adeno-associated virus (rAAV) depending on the serotype and genome structure, such as single-stranded (ss) and self-complementary (sc).
Nuri Oh, Naresh H. Tarte
doaj   +1 more source

Influenza A virus RNA polymerase structures provide insights into viral genome replication

open access: yesNature, 2019
Influenza A viruses are responsible for seasonal epidemics, and pandemics can arise from the transmission of novel zoonotic influenza A viruses to humans1,2.
H. Fan   +11 more
semanticscholar   +1 more source

Transcriptomics Reveal Antiviral Gene Induction in the Egyptian Rousette Bat Is Antagonized In Vitro by Marburg Virus Infection

open access: yesViruses, 2018
The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral responses.
Catherine E. Arnold   +7 more
doaj   +1 more source

Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication.

open access: yesCell, 2019
Positive-stranded RNA viruses extensively remodel host cell architecture to enable viral replication. Here, we examined the poorly understood formation of specialized membrane compartments that are critical sites for the synthesis of the viral genome. We
Orly Laufman, J. Perrino, R. Andino
semanticscholar   +1 more source

Distribution and conservation of Banana Streak Virus (BSV) within banana Musa balbisiana genome: what impact on host and virus evolution ? [PDF]

open access: yes, 2011
The nuclear genome of several plants isinvaded by numerous viral sequences. These integrations correspond to accidental events mainly resulting from illegitimate recombination of DNA viruses belonging to the family Caulimoviridae with plant DNA whereas ...
Chabannes, Matthieu   +4 more
core   +2 more sources

Telomeres and Viruses: Common Themes of Genome Maintenance

open access: yesFrontiers in Oncology, 2012
Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng   +2 more
doaj   +1 more source

Sherlock Genomes — viral investigator [PDF]

open access: yesNature Reviews Microbiology, 2013
This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes.
Smith, Sarah E., Wash, Rachael S.
openaire   +2 more sources

Non-Viral Delivery To Enable Genome Editing.

open access: yesTrends in Biotechnology, 2019
Genome-editing technologies such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENS), and the clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein system have revolutionized biological
Y. Rui, David R. Wilson, J. Green
semanticscholar   +1 more source

Molecular characterisation of integrated sequences of Banana streak virus in the banana plant genome [PDF]

open access: yes, 2009
The genome of banana (Musa sp.) harbours multiple integrations of several species of Banana streak virus (BSV), certainly resulting from illegitimate recombination between host and viral DNA. Surprisingly, this pararetrovirus does not require integration
Baurens, Franc-Christophe   +6 more
core   +2 more sources

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy [PDF]

open access: yes, 2018
G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in ...
Richter, Sara N, Ruggiero, Emanuela
core   +1 more source

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