MosaicSolver : a tool for determining recombinants of viral genomes from pileup data [PDF]
, 2014 Viral recombination is a key evolutionary mechanism, aiding escape from host immunity, contributing to changes in tropism and possibly assisting transmission across species barriers.
Burroughs, Nigel +8 more
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Sherlock Genomes — viral investigator [PDF]
Nature Reviews Microbiology, 2013 This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes.
Smith, Sarah E., Wash, Rachael S.
openaire +2 more sources
Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. [PDF]
, 2012 BACKGROUND: Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus of the Reoviridae family, which encodes its genes in ten linear dsRNA segments.
Roy Polly +8 more
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Viruses, 2018 The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral responses.
Catherine E. Arnold +7 more
doaj +1 more source
Subcellular distribution of the rAAV genome depends on genome structure
Scientific Reports, 2023 Many studies have been conducted on the transduction efficiency of recombinant adeno-associated virus (rAAV) depending on the serotype and genome structure, such as single-stranded (ss) and self-complementary (sc).
Nuri Oh, Naresh H. Tarte
doaj +1 more source
Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]
, 2009 Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr +9 more
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Telomeres and Viruses: Common Themes of Genome Maintenance
Frontiers in Oncology, 2012 Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng +2 more
doaj +1 more source
Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]
, 2014 The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
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The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal [PDF]
, 2012 Transcription termination of the mRNA produced from the small (S) genome segment of Bunyamwera orthobunyavirus (BUNV) has previously been mapped to two cis-acting sequences located within the 5′ UTR using a virus-free replication assay.
Elliott, Richard Michael +5 more
core +1 more source
Genome Editing Strategies to Protect Livestock from Viral Infections
, 2021 The livestock industry is constantly threatened by viral disease outbreaks, including infections with zoonotic potential. While preventive vaccination is frequently applied, disease control and eradication also depend on strict biosecurity measures ...
Jenny-Helena Söllner +2 more
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