Results 21 to 30 of about 516,921 (266)

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

open access: yesmSphere, 2019
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents
Joseph Prescott   +11 more
doaj   +1 more source

The complexity landscape of viral genomes

open access: yesGigaScience, 2022
Abstract Background Viruses are among the shortest yet highly abundant species that harbor minimal instructions to infect cells, adapt, multiply, and exist. However, with the current substantial availability of viral genome sequences, the scientific repertory lacks a complexity landscape that ...
Jorge Miguel Silva   +3 more
openaire   +3 more sources

Subcellular distribution of the rAAV genome depends on genome structure

open access: yesScientific Reports, 2023
Many studies have been conducted on the transduction efficiency of recombinant adeno-associated virus (rAAV) depending on the serotype and genome structure, such as single-stranded (ss) and self-complementary (sc).
Nuri Oh, Naresh H. Tarte
doaj   +1 more source

Transcriptomics Reveal Antiviral Gene Induction in the Egyptian Rousette Bat Is Antagonized In Vitro by Marburg Virus Infection

open access: yesViruses, 2018
The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral responses.
Catherine E. Arnold   +7 more
doaj   +1 more source

Sherlock Genomes — viral investigator [PDF]

open access: yesNature Reviews Microbiology, 2013
This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes.
Smith, Sarah E., Wash, Rachael S.
openaire   +2 more sources

Telomeres and Viruses: Common Themes of Genome Maintenance

open access: yesFrontiers in Oncology, 2012
Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng   +2 more
doaj   +1 more source

Icosahedral Packing of RNA Viral Genomes [PDF]

open access: yesPhysical Review Letters, 2005
4 pages revtex, 4 eps ...
Rudnick, Joseph, Bruinsma, Robijn
openaire   +3 more sources

Isolation, Characterization, and Differentiation Potential of Canine Adipose-Derived Stem Cells

open access: yesCell Transplantation, 2010
Adipose tissue may represent a potential source of adult stem cells for tissue engineering applications in veterinary medicine. It can be obtained in large quantities, under local anesthesia, and with minimal discomfort.
N. M. Vieira   +5 more
doaj   +1 more source

Viral Genome Compression

open access: yes, 2006
Viruses compress their genome to reduce space. One of the main techniques is overlapping genes. We model this process by the shortest common superstring problem, that is, we look for the shortest genome which still contains all genes. We give an algorithm for computing optimal solutions which is slow in the number of strings but fast (linear) in their ...
Lucian Ilie   +3 more
openaire   +1 more source

Alvira: comparative genomics of viral strains [PDF]

open access: yesBioinformatics, 2007
Abstract Motivation: The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large number of viral strains.
Enault, François   +3 more
openaire   +5 more sources

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