Results 31 to 40 of about 2,630,320 (343)

Introducing the Bacterial and Viral Bioinformatics Resource Center (BV-BRC): a resource combining PATRIC, IRD and ViPR

Nucleic Acids Res., 2022
The National Institute of Allergy and Infectious Diseases (NIAID) established the Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the growing body of genome sequence and other omics-related data.
R. Olson, Rida Assaf, T. Brettin, Neal Conrad, Clark Cucinell, James J. Davis, D. M. Dempsey, A. Dickerman, Emily M. Dietrich, Ron Kenyon, M. Kuscuoglu, E. Lefkowitz, Jian Lu, D. Machi, C. Macken, Chunhong Mao, A. Niewiadomska, M. Nguyen, G. Olsen, Jamie C. Overbeek, B. Parrello, Victoria A. Parrello, Jacob Porter, G. Pusch, Maulik Shukla, Indresh Singh, Lucy Stewart, G. Tan, Chris Thomas, Margo VanOeffelen, Veronika Vonstein, Zachary S. Wallace, A. Warren, A. Wattam, Fangfang Xia, H. Yoo, Yun Zhang, C. Zmasek, R. Scheuermann, R. Stevens   +39 more
semanticscholar   +1 more source

Genomics in Plant Viral Research

Viruses, 2022
Plant viruses constitute a large group of pathogens causing damaging diseases in many agricultural and horticultural crops around the world [...]
Solomon Maina, Brendan Rodoni
openaire   +3 more sources

Genomic epidemiology of SARS-CoV-2 virus with a bioinformatics platform

Universidad Médica Pinareña, 2020
Introduction: viral epidemics have presented a risk to human health since they can turn into pandemics and affect a large part of the population, especially for poor developing countries. In 2020, the worldwide pandemic of COVID-19 is underway.
Sebastian Iglesias-Osores, Percy Omar Tullume-Vergara, Johana Acosta-Quiroz, Johnny Leandro Saavedra-Camacho, Arturo Rafael-Heredia   +4 more
doaj   +2 more sources

Emerging coronaviruses: Genome structure, replication, and pathogenesis

Journal of Medical Virology, 2020
The recent emergence of a novel coronavirus (2019‐nCoV), which is causing an outbreak of unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of the risk of CoVs posed to public health.
Yu Chen, Qianyun Liu, D. Guo
semanticscholar   +1 more source

Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle? [PDF]

, 2013
DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes.
Sinclair, Alison J
core   +2 more sources

Comparison of the Gene Coding Contents and Other Unusual Features of the GC-Rich and AT-Rich Branch Probosciviruses

mSphere, 2016
Nearly 100 cases of lethal acute hemorrhagic disease in young Asian elephants have been reported worldwide. All tested cases contained high levels of elephant endotheliotropic herpesvirus (EEHV) DNA in pathological blood or tissue samples.
Paul D. Ling, Simon Y. Long, Jian-Chao Zong, Sarah Y. Heaggans, Xiang Qin, Gary S. Hayward   +5 more
doaj   +1 more source

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

mSphere, 2019
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents
Joseph Prescott, Jonathan C. Guito, Jessica R. Spengler, Catherine E. Arnold, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Lisa W. Guerrero, Gustavo F. Palacios, Mariano Sanchez-Lockhart, Cesar G. Albariño, Jonathan S. Towner   +11 more
doaj   +1 more source

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

Nature Communications, 2019
Programmable nucleases have enabled rapid and accessible genome engineering in eukaryotic cells and living organisms. However, their delivery into target cells can be technically challenging when working with primary cells or in vivo.
P. Mangeot, V. Risson, F. Fusil, A. Marnef, Emilie Laurent, Juliana Blin, V. Mournetas, E. Massouridès, Thibault J. M. Sohier, A. Corbin, Fabien Aubé, Marie Teixeira, C. Pinset, L. Schaeffer, G. Legube, F. Cosset, E. Verhoeyen, T. Ohlmann, Emiliano P. Ricci   +18 more
semanticscholar   +1 more source

The complexity landscape of viral genomes

GigaScience, 2022
Abstract Background Viruses are among the shortest yet highly abundant species that harbor minimal instructions to infect cells, adapt, multiply, and exist. However, with the current substantial availability of viral genome sequences, the scientific repertory lacks a complexity landscape that ...
Jorge Miguel Silva, Diogo Pratas, Tânia Caetano, Sérgio Matos   +3 more
openaire   +3 more sources

Reprogramming human T cell function and specificity with non-viral genome targeting

Nature, 2017
Decades of work have aimed to genetically reprogram T cells for therapeutic purposes1,2 using recombinant viral vectors, which do not target transgenes to specific genomic sites3,4.
Theodore L. Roth, Cristina Puig-Saus, R. Yu, E. Shifrut, J. Carnevale, P. J. Li, J. Hiatt, Justin Saco, Paige Krystofinski, Han Li, Victoria R. Tobin, David N. Nguyen, Michael R. Lee, A. Putnam, A. Ferris, Jeff W. Chen, J. Schickel, Laurence Pellerin, D. Carmody, G. Alkorta-Aranburu, D. del Gaudio, Hiroyuki Matsumoto, Montse Morell, Y. Mao, M. Cho, R. Quadros, C. Gurumurthy, Baz Smith, M. Haugwitz, S. Hughes, J. Weissman, Kathrin Schumann, Jonathan H. Esensten, Andy P May, A. Ashworth, Gary M. Kupfer, S. Greeley, R. Bacchetta, E. Meffre, M. Roncarolo, Neil Romberg, K. Herold, A. Ribas, M. Leonetti, A. Marson   +44 more
semanticscholar   +1 more source