Results 51 to 60 of about 2,630,320 (343)

Isolation, Characterization, and Differentiation Potential of Canine Adipose-Derived Stem Cells

open access: yesCell Transplantation, 2010
Adipose tissue may represent a potential source of adult stem cells for tissue engineering applications in veterinary medicine. It can be obtained in large quantities, under local anesthesia, and with minimal discomfort.
N. M. Vieira   +5 more
doaj   +1 more source

Icosahedral Packing of RNA Viral Genomes [PDF]

open access: yesPhysical Review Letters, 2005
4 pages revtex, 4 eps ...
Rudnick, Joseph, Bruinsma, Robijn
openaire   +3 more sources

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy

open access: yesNature Communications, 2023
Dilated cardiomyopathy is the second most common cause for heart failure with no cure except a high-risk heart transplantation. Approximately 30% of patients harbor heritable mutations which are amenable to CRISPR-based gene therapy.
Markus Grosch   +17 more
doaj   +1 more source

A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. [PDF]

open access: yes, 2014
UnlabelledPairing high-throughput sequencing technologies with high-throughput mutagenesis enables genome-wide investigations of pathogenic organisms. Knowledge of the specific functions of protein domains encoded by the genome of the hepatitis C virus ...
Arumugaswami, Vaithilingaraja   +14 more
core   +2 more sources

Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities.

open access: yesBiomaterials, 2018
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas (CRISPR-associated) genome editing systems have become one of the most robust platforms in basic biomedical research and therapeutic applications.
Ling Li, Shuo Hu, Xiaoyuan Chen
semanticscholar   +1 more source

CheckV assesses the quality and completeness of metagenome-assembled viral genomes

open access: yesNature Biotechnology, 2020
Millions of new viral sequences have been identified from metagenomes, but the quality and completeness of these sequences vary considerably. Here we present CheckV, an automated pipeline for identifying closed viral genomes, estimating the completeness ...
Stephen Nayfach   +5 more
semanticscholar   +1 more source

The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection

open access: yesmSystems, 2022
Human cells identify invading pathogens and activate immune signaling pathways through a wide array of pattern recognition receptors, including DNA sensors.
Timothy R. Howard   +3 more
doaj   +1 more source

Viral genome integration of canine papillomavirus 16

open access: yesPapillomavirus Research, 2019
Papillomaviruses infect humans and animals, most often causing benign proliferations on skin or mucosal surfaces. Rarely, these infections persist and progress to cancer.
Jennifer Luff   +5 more
doaj   +1 more source

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]

open access: yes, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Boyd, Joseph R.   +12 more
core   +1 more source

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

open access: yesNature Biotechnology, 2016
The combination of Cas9, guide RNA and repair template DNA can induce precise gene editing and the correction of genetic diseases in adult mammals. However, clinical implementation of this technology requires safe and effective delivery of all of these ...
Hao Yin   +21 more
semanticscholar   +1 more source

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