Results 21 to 30 of about 1,251,540 (276)
Virtual in situs: Sequencing mRNA from cryo-sliced Drosophila embryos to determine genome-wide spatial patterns of gene expression [PDF]
, 2013 Complex spatial and temporal patterns of gene expression underlie embryo differentiation, yet methods do not yet exist for the efficient genome-wide determination of spatial expression patterns during development.
Combs, Peter A., Eisen, Michael B.
core +18 more sources
Unbiased population heterozygosity estimates from genome‐wide sequence data
Methods in Ecology and Evolution, 2021 Heterozygosity is a metric of genetic variability frequently used to inform the management of threatened taxa. Estimating observed and expected heterozygosities from genome‐wide sequence data has become increasingly common, and these estimates are often ...
Thomas L. Schmidt +3 more
doaj +1 more source
Common variants in FOXP1 are associated with generalized vitiligo [PDF]
, 2010 In a recent genome-wide association study of generalized vitiligo, we identified ten confirmed susceptibility loci. By testing additional loci that showed suggestive association in the genome-wide study, using two replication cohorts of European descent,
A Alkhateeb +34 more
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A concise history of genome-wide association studies
Saudi Journal of Medicine and Medical Sciences, 2013 Genome-wide association studies (GWASs) have had a tremendous impact on the pace of genomic research of common diseases. The number of identified genetic variants associated has grown exponentially. For some diseases, such as coronary heart disease (CHD),
Bobby P. C. Koeleman +3 more
doaj +1 more source
Unconventional machine learning of genome-wide human cancer data
, 2020 Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide perspective ...
Bajaj, Sweta R. +7 more
core +1 more source
H3AGWAS: a portable workflow for genome wide association studies
BMC Bioinformatics, 2022 Background Genome-wide association studies (GWAS) are a powerful method to detect associations between variants and phenotypes. A GWAS requires several complex computations with large data sets, and many steps may need to be repeated with varying ...
Jean-Tristan Brandenburg +6 more
doaj +1 more source
Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]
, 2013 <p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J. +4 more
core +3 more sources
Genome-wide approaches to schizophrenia [PDF]
Brain Research Bulletin, 2010 Schizophrenia (SZ) is a common and severe psychiatric disorder with both environmental and genetic risk factors, and a high heritability. After over 20 years of molecular genetics research, new molecular strategies, primarily genome-wide association studies (GWAS), have generated major tangible progress.
Jubao, Duan +2 more
openaire +2 more sources
Cancer gene prioritization by integrative analysis of mRNA expression and DNA copy number data: a comparative review [PDF]
, 2011 A variety of genome-wide profiling techniques are available to probe complementary aspects of genome structure and function. Integrative analysis of heterogeneous data sources can reveal higher-level interactions that cannot be detected based on ...
Akavia +30 more
core +2 more sources
The future is genome-wide [PDF]
Genome Biology, 2006 A report of the annual meeting of the European Society of Human Genetics, Amsterdam, 6-9 May 2006.
Deutsch, S., Reymond, A.
openaire +2 more sources