Results 131 to 140 of about 98,968 (210)

Does COMT Play a Role in Parkinson's Disease Susceptibility across Diverse Ancestral Populations?

Movement Disorders, EarlyView.
Abstract Background The catechol‐O‐methyltransferase (COMT) gene is involved in brain catecholamine metabolism, but its association with Parkinson's disease (PD) risk remains unclear. Objective Our aim was to investigate the relationship between COMT genetic variants and PD risk across diverse ancestries.
Miguel Martín‐Bórnez, Nisar Shar, Mohamed Ahmed Nour, David Murphy, Inas Elsayed, Megha Shri Nanjundaswamy, Francisca Nwaokorie, Adedunni Olusanya, Nicole Kuznetsov, Sara Bandres‐Ciga, Alastair J. Noyce, Hirotaka Iwaki, Lietsel Jones, Pilar Gómez‐Garre, Pablo Mir, The Global Parkinson's Genetics Program (GP2), María Teresa Periñán   +16 more
wiley   +1 more source

Rare but Relevant? Assessing Variants in Dystonia‐Linked Genes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Dystonia and Parkinson's disease (PD) exhibit clinical and genetic overlap, but the relevance of dystonia gene variants in PD remains unclear. Objective The aim was to assess the frequency of dystonia‐linked pathogenic variants in PD.
Lara M. Lange, Zih‐Hua Fang, Laurel Screven, Ai Huey Tan, Roy N. Alcalay, Rim Amouri, Roberta Bovenzi, Matilda Fenn, Joshua L.I. Frost, Joseph Jankovic, Simona Jasaityte, Zane Jaunmuktane, Beomseok Jeon, Ignacio Juan Keller Sarmiento, Rejko Krüger, Gregor Kuhlenbäumer, Chin‐Hsien Lin, Lukas Pavelka, Maria Teresa Periñan, Samia Ben Sassi, Tommaso Schirinzi, Jung Hwan Shin, Joshua M. Shulman, Yi Wen Tay, Ryan Uitti, Tom Warner, Zbigniew K. Wszolek, Lesley Wu, Ruey‐Meei Wu, Kirsten E. Zeuner, Cornelis Blauwendraat, Andrew Singleton, Niccolò E. Mencacci, Huw R. Morris, Shen‐Yang Lim, Katja Lohmann, Christine Klein, the Global Parkinson's Genetics Program (GP2)   +37 more
wiley   +1 more source

MOESM1 of Genome-wide association study (GWAS) for morphological and yield-related traits in an oil palm hybrid (Elaeis oleifera x Elaeis guineensis) population

, 2019
Jaime A. Osorio-Guarín, Gina A. Garzón-Martínez, Paola Delgadillo-Durán, Silvio Bastidas, Leidy Paola Moreno, Felix E. Enciso-Rodríguez, Omar E. Cornejo, Luz Stella Barrero   +7 more
openalex   +1 more source

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines [PDF]

, 2014
Jin Yang, Yao Li, Lawrence Chan, Yi-Ting Tsai, Wen-Hsuan Wu, Huy Nguyen, Chun‐Wei Hsu, Xiaorong Li, Lewis M. Brown, Dieter Egli, Janet R. Sparrow, Stephen H. Tsang   +11 more
openalex   +1 more source

Interactive Bioinformatics Lab: Using Genomic Databases for Active Learning in Dentistry

Journal of Dental Education, EarlyView.
François Isnaldo Dias Caldeira, Raquel Mantuaneli Scarel‐Caminaga   +1 more
wiley   +1 more source

GBA1 Variants with Unknown Classification Are Modest Contributors to Parkinson's Disease Susceptibility

Movement Disorders, EarlyView.
Abstract Background GBA1 variants cause Gaucher's disease (GD) in biallelic forms and increase Parkinson's disease (PD) risk in heterozygous carriers. Carriers of mild or severe variants (causing GD type 1 or types 2–3) can enroll in clinical trials, whereas those with GBA1 variants classified as unknown are typically excluded.
Sitki Cem Parlar, Yoomin Lee, Ziv Gan‐Or   +2 more
wiley   +1 more source

Casual Genes of Schizophrenia Detected by Genome-Wide Association Study (GWAS)

, 2014
高橋 栄
openalex   +2 more sources

Extreme‐phenotype genome‐wide association study (XP‐GWAS): a method for identifying trait‐associated variants by sequencing pools of individuals selected from a diversity panel [PDF]

, 2015
Jinliang Yang, Haiying Jiang, Cheng‐Ting Yeh, Jianming Yu, Jeffrey A. Jeddeloh, Dan Nettleton, Patrick S. Schnable   +6 more
openalex   +1 more source

Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten, LaTasha K. Crawford, Elise J. B. De, Wencheng Li, Yoshiyuki Akiyama   +4 more
wiley   +1 more source

Genome-wide Association Study (GWAS) for Mesocotyl Elongation in Rice (Oryza sativa L.) under Multiple Culture Conditions. [PDF]

Genes (Basel), 2019
Liu H, Zhan J, Li J, Lu X, Liu J, Wang Y, Zhao Q, Ye G.   +7 more
europepmc   +1 more source