Results 151 to 160 of about 115,431 (259)

Estimated Body Fat Percentage and Triglyceride‐Glucose Index for Identifying MASLD in Lean Asian Adults: A Cross‐Sectional Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong, Ya‐Li Chen, Rui Li, Lu‐Xiang Shang, Sha Sha   +4 more
wiley   +1 more source

A SNP-based genome-wide association study (GWAS) of seed-yield related traits in <i>Psathyrostachys juncea</i> using wheat as a reference genome. [PDF]

PeerJ
Li Z, Wang T, Ren X, Han F, Ma Y, Yun L.
europepmc   +1 more source

A Genome-Wide Association Study (GWAS) meta-analysis of post-traumatic osteoarthritis of the knee (GO-PTOA): Protocol for Analysis Plan

, 2023
McDonald M, Richman J, Boer C, Kalsoum R, Dochtermann D, Barker T, Briem K, Hatzikotoulas K, Hollis B, Jostins-Dean L, Magi R, Reimann E, EstBB Research Team, Southam L, Styrkarsdottir U, Tiwari H, Van Meurs J, Zeggini E, Singh J, Watt FE.   +19 more
europepmc   +1 more source

Accelerated Biological Aging Increases the Risk of Head and Neck Cancer: Insights From Genetic Instruments of Epigenetic Clocks

Molecular Carcinogenesis, EarlyView.
ABSTRACT Epigenetic clocks are robust biomarkers of biological aging and have been associated with cancer susceptibility. However, the relationship between genetically predicted epigenetic age acceleration and head and neck cancer risk remains unclear. Using a large case‐control study of 2189 head and neck squamous cell carcinoma (HNSCC) cases and 2189
Jiaqi Wang, Jie Deng, Yifan Xu, Chia‐Wen Tsai, Wen‐Shin Chang, Yang Deng, Maosheng Huang, Da‐Tian Bau, Guojun Li, Jian Gu   +9 more
wiley   +1 more source

Uncovering the genomic basis of phenological traits in <i>Chouardia litardierei</i> (Asparagaceae) through a genome-wide association study (GWAS). [PDF]

Front Plant Sci
Šarančić SL, Pleić N, Križanović K, Surina B, Mitić D, Radosavljević I.   +5 more
europepmc   +1 more source

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

Med Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang, Chenchen Wang, Tianliang Liu, Ziliang Wang, Zhe Zhang   +4 more
wiley   +1 more source

Genome Wide Association Study (GWAS) Identifies Novel Genetic Loci for Second-Generation Antipsychotics (SGA)-Induced Metabolic Syndrome (MetS). [PDF]

Clin Transl Sci
El Rouby N, Owusu-Obeng A, Preuss MH, Lee S, Shi M, Nadukuru R, Van Driest SL, Mosley JD, DelBello M.   +8 more
europepmc   +1 more source

Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. [PDF]

Int J Mol Sci, 2020
Nedoszytko B, Sobalska-Kwapis M, Strapagiel D, Lange M, Górska A, Elberink JNGO, van Doormaal J, Słomka M, Kalinowski L, Gruchała-Niedoszytko M, Nowicki RJ, Valent P, Niedoszytko M.   +12 more
europepmc   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

Med Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen, Chunrun Qu, Zeyu Wang, Jinglin Zhou, Hongwei Liu, Yingjie Li, Bowei Liu, Hao Zhang, Nan Zhang, Jingwei Zhang, Quan Cheng   +10 more
wiley   +1 more source

Genome-wide association study (GWAS) for body weights of sussex cattle (Bos taurus) in South Africa. [PDF]

Heliyon
Bila L, Putra WPB, Malatji DP, Sanarana YP, Tyasi TL.   +4 more
europepmc   +1 more source