Results 151 to 160 of about 115,835 (257)

Whole Exome Sequencing Identified a Novel Mutation in the LOXHD1 Gene in Consanguineous Iranian Families With Hearing Loss

Journal of Clinical Laboratory Analysis, EarlyView.
Whole exome sequencing in a consanguineous Iranian family with autosomal recessive non‐syndromic hearing loss revealed a novel homozygous frameshift mutation, c.3713dupA (p.Asp1238Glufs*10), in the LOXHD1 gene. This mutation, located in exon 24, results in a premature stop codon and a truncated protein. Sanger sequencing confirmed co‐segregation of the
Solmaz Hassani Fard Katiraei, Milad Gholami, Mohsen Soosanabadi, Mona Entezam, Seyed Alireza Dastgheib   +4 more
wiley   +1 more source

Uncovering the genomic basis of phenological traits in <i>Chouardia litardierei</i> (Asparagaceae) through a genome-wide association study (GWAS). [PDF]

Front Plant Sci
Šarančić SL, Pleić N, Križanović K, Surina B, Mitić D, Radosavljević I.   +5 more
europepmc   +1 more source

A Genome-Wide Association Study (GWAS) meta-analysis of post-traumatic osteoarthritis of the knee (GO-PTOA): Protocol for Analysis Plan

, 2023
McDonald M, Richman J, Boer C, Kalsoum R, Dochtermann D, Barker T, Briem K, Hatzikotoulas K, Hollis B, Jostins-Dean L, Magi R, Reimann E, EstBB Research Team, Southam L, Styrkarsdottir U, Tiwari H, Van Meurs J, Zeggini E, Singh J, Watt FE.   +19 more
europepmc   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

A SNP-based genome-wide association study (GWAS) of seed-yield related traits in <i>Psathyrostachys juncea</i> using wheat as a reference genome. [PDF]

PeerJ
Li Z, Wang T, Ren X, Han F, Ma Y, Yun L.
europepmc   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

JCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave, Marthe de Roo, Charlotte Vrijen, Tina Kretschmer   +3 more
wiley   +1 more source

Genome Wide Association Study (GWAS) Identifies Novel Genetic Loci for Second-Generation Antipsychotics (SGA)-Induced Metabolic Syndrome (MetS). [PDF]

Clin Transl Sci
El Rouby N, Owusu-Obeng A, Preuss MH, Lee S, Shi M, Nadukuru R, Van Driest SL, Mosley JD, DelBello M.   +8 more
europepmc   +1 more source

Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. [PDF]

Int J Mol Sci, 2020
Nedoszytko B, Sobalska-Kwapis M, Strapagiel D, Lange M, Górska A, Elberink JNGO, van Doormaal J, Słomka M, Kalinowski L, Gruchała-Niedoszytko M, Nowicki RJ, Valent P, Niedoszytko M.   +12 more
europepmc   +1 more source

Unpacking early risks for peer victimization: A network analysis of early temperament and polygenic risk scores

JCPP Advances, EarlyView.
Abstract Background Children who show difficult temperament are at risk of peer victimisation, which in turn associates with numerous negative outcomes later in life. We used network analysis to examine whether specific aspects of difficult temperament contributed to these associations, and whether the links were moderated by variations in genetic ...
Tom C.‐H. Wu, Deniz Konac, Liliana Garcia‐Mondragon, Alex F. Martin, Barbara Maughan, Ted Barker   +5 more
wiley   +1 more source

Genome-wide association study (GWAS) for body weights of sussex cattle (Bos taurus) in South Africa. [PDF]

Heliyon
Bila L, Putra WPB, Malatji DP, Sanarana YP, Tyasi TL.   +4 more
europepmc   +1 more source