Results 171 to 180 of about 42,338,399 (265)

Maternal microbiota shapes brain and neuroendocrine development in piglets

open access: yesiMeta, EarlyView.
Using germ‐free and maternal microbiota‐transplanted piglets, we constructed an integrated multi‐organ atlas combining snRNA‐seq, Stereo‐seq, intestinal transcriptomics, and metabolomics. Maternal microbiota transplantation was associated with neuronal and glial remodeling, altered neuron–glia communication involving NRG1/3–ERBB4 signaling, trends ...
Leli Wang   +20 more
wiley   +1 more source

Genome-wide association study (GWAS) identifies genetic loci controlling Distinctness, Uniformity, and Stability (DUS) traits in wheat. [PDF]

open access: yesTheor Appl Genet
Zanella CM   +11 more
europepmc   +1 more source

Integrative genomics and regulomics reveal the molecular architecture of complex traits in domestic chickens

open access: yesiMeta, EarlyView.
Domestic chickens (Gallus gallus domesticus) exhibit exceptional phenotypic diversity and provide a valuable model for studying domestication and artificial selection. We integrated whole‐genome resequencing data from ~3000 individuals with 20 slaughter‐related traits.
Wei Han   +19 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang   +7 more
wiley   +1 more source

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