Sorghum T2T pangenome highlights comprehensive genomic variation
Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang +10 more
wiley +1 more source
Prioritization of Osteoporosis-Associated Genome-wide Association Study (GWAS) Single-Nucleotide Polymorphisms (SNPs) Using Epigenomics and Transcriptomics. [PDF]
Zhang X, Deng HW, Shen H, Ehrlich M.
europepmc +1 more source
Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children
Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao +9 more
wiley +1 more source
Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. [PDF]
Li Z +5 more
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Genome-Wide Association Study (GWAS) for Freezing and De-Acclimation Tolerance in Polish Winter Barley. [PDF]
Bani I, Hadagali S, Wójcik-Jagła M.
europepmc +1 more source
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Identification of Gene Associated with Sweetness in Corn (Zea mays L.) by Genome-Wide Association Study (GWAS) and Development of a Functional SNP Marker for Predicting Sweet Corn. [PDF]
Ruanjaichon V +11 more
europepmc +1 more source
Infection mechanisms of Rhizoctonia cerealis in wheat
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren +13 more
wiley +1 more source
Genome-wide association study (GWAS) and transcriptome analysis reveal new candidate genes for leaf size in alfalfa. [PDF]
Zhang Y +9 more
europepmc +1 more source

