Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser +6 more
wiley +1 more source
Genome-Wide Association Study (GWAS) for Left Displaced Abomasum in Highly Productive Russian Holstein Cattle. [PDF]
Plemyashov K +4 more
europepmc +1 more source
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) and language/reading difficulties frequently co‐occur. The extent of shared genetic architecture remains incompletely defined. We investigated genome‐wide overlap between ADHD and four core skills: word reading, nonword reading, spelling, and phoneme awareness.
Jinzhu Zhao +5 more
wiley +1 more source
Genome-wide association study (GWAS) analyses of early anatomical changes in rose adventitious root formation. [PDF]
Wamhoff D +5 more
europepmc +1 more source
Genome-wide association study (GWAS) reveals genetic loci of lead (Pb) tolerance during seedling establishment in rapeseed (Brassica napus L.). [PDF]
Zhang F +6 more
europepmc +1 more source
Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Genome-wide association study (GWAS) uncovers candidate genes linked to the germination performance of bread wheat (Triticum aestivum L.) under salt stress. [PDF]
Javid S +6 more
europepmc +1 more source
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann +30 more
wiley +1 more source
Is quinoa‐farming sustainable in marginal environments? Social, economical and environmental aspects
Abstract Quinoa (Chenopodium quinoa Willd.) is an Andean grain crop introduced as a novel crop to many parts of the world in recent years. Recognized for nutritious seeds and high abiotic stress tolerance, it has been promoted as an element of climate‐resilient agriculture, particularly in marginal environments.
Anna Tabea Mengen +5 more
wiley +1 more source
Genome-Wide Association Study (GWAS) for Identifying SNPs and Genes Related to Phosphate-Induced Phenotypic Traits in Tomato (Solanum lycopersicum L.). [PDF]
Hakla HR +10 more
europepmc +1 more source

