Results 181 to 190 of about 42,338,399 (265)

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

Genome-Wide Association Study (GWAS)-Derived Type 2 Diabetes Risk Variants in Gestational Diabetes Mellitus: Evidence From North India. [PDF]

Cureus
Shakir Z, Pandey A, A Alsayegh A, Fahad Alshahrani A, Ashfaq F, Khan M, Ali W.   +6 more
europepmc   +1 more source

Shared genetics between ADHD and reading/language abilities: Genome‐wide correlations, stratified enrichment, cross‐trait association, and mendelian randomization

JCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) and language/reading difficulties frequently co‐occur. The extent of shared genetic architecture remains incompletely defined. We investigated genome‐wide overlap between ADHD and four core skills: word reading, nonword reading, spelling, and phoneme awareness.
Jinzhu Zhao, Shi Huang, Wei Liu, Feng Wang, Hong Qian, Xiaolin Hu   +5 more
wiley   +1 more source

Genome-Wide Association Study (GWAS) on Reproductive Seasonality in Indigenous Greek Sheep Breeds: Insights into Genetic Integrity. [PDF]

Curr Issues Mol Biol
Antonopoulou D, Symeon G, Zaralis K, Avdi M, Frydas IS, Giantsis IA.   +5 more
europepmc   +1 more source

Multivariate genetic analyses test for the presence of a general ‘n’ factor underlying neurodevelopmental conditions

JCPP Advances, EarlyView.
Abstract Background Neurodevelopmental conditions often emerge early in life and have substantial genetic influences. There are significant genetic correlations between neurodevelopmental conditions, such as between autism spectrum disorder (Autism) and attention deficit‐hyperactivity disorder (ADHD), and they are listed together in diagnostic manuals.
Morgan James Morgan, Margherita Malanchini, Elise B. Robinson, Angelica Ronald   +3 more
wiley   +1 more source

Genome-wide association study (GWAS) provides insights into the genomic basis of reproduction-related traits in Chouardia litardierei (Asparagaceae). [PDF]

BMC Plant Biol
Šarančić SL, Pleić N, Mitić D, Križanović K, Surina B, Radosavljević I.   +5 more
europepmc   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source

Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS). [PDF]

Breed Sci
Mukamuhirwa F, Shirasawa K, Naito K, Rurangwa E, Ndayizeye V, Nyombayire A, Muhire JP, Govindaraj M, Ohtake N, Okazaki K, Okada M, Fukai E.   +11 more
europepmc   +1 more source

Genetic loci determining potato starch yield and granule morphology revealed by genome-wide association study (GWAS). [PDF]

PeerJ, 2020
Khlestkin VK, Erst TV, Rozanova IV, Efimov VM, Khlestkina EK.   +4 more
europepmc   +1 more source

Estimated Body Fat Percentage and Triglyceride‐Glucose Index for Identifying MASLD in Lean Asian Adults: A Cross‐Sectional Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong, Ya‐Li Chen, Rui Li, Lu‐Xiang Shang, Sha Sha   +4 more
wiley   +1 more source