Results 111 to 120 of about 115,431 (259)

Editorial: Genetics of Complex Traits and Diseases From Under-Represented Populations

open access: yesFrontiers in Genetics, 2022
Segun Fatumo   +5 more
doaj   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik   +4 more
wiley   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

open access: yesiMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng   +20 more
wiley   +1 more source

Editorial: Wheat biofortification to alleviate global malnutrition

open access: yesFrontiers in Nutrition, 2022
Maria Itria Ibba   +6 more
doaj   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

open access: yesiMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif   +4 more
wiley   +1 more source

Predicting allergic diseases in children using genome-wide association study (GWAS) data and family history. [PDF]

open access: yesWorld Allergy Organ J, 2021
Park J   +8 more
europepmc   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

open access: yesiMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou   +8 more
wiley   +1 more source

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