Results 91 to 100 of about 42,338,399 (265)

SUPERSEDED - Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults - BayesR+ GWAS Proteins

open access: yes, 2020
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2854 ## This dataset represents one of five datasets which correspond to the study: "Multi-method genome and epigenome wide studies of inflammatory protein levels ...
Evans, Kathryn   +18 more
core   +1 more source

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]

open access: yes, 2011
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...
Palmer Cameron D.   +799 more
core   +3 more sources

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

open access: yesAdvanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu   +11 more
wiley   +1 more source

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function [PDF]

open access: yes, 2011
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 second and the ratio of forced expiratory volume in 1 ...
Stricker, Bruno H. Ch   +903 more
core   +1 more source

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications

open access: yesAGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +1 more source

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies [PDF]

open access: yes, 2012
<p>Background - Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less.
Furie, K.   +391 more
core   +1 more source

Biparental Crossing and QTL Mapping for Validation of Genome-Wide Association Studies

open access: yes, 2022
Association mapping (AM), also known as genome-wide association studies (GWAS), is increasingly being employed in crop plants for the identification of QTL/genes and marker–trait associations (MTAs) in natural populations.
Singh, R   +3 more
core   +1 more source

Genetic Variation in ADHD‐Related Risk Genes in an Indigenous Population of the Amazon

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Attention‐Deficit/Hyperactivity Disorder (ADHD) is a highly heritable neurodevelopmental disorder; however, its genetic architecture remains poorly explored in Indigenous populations. This study aimed to analyze and characterize genetic variation in 11 genes (ADGRL3, CDH8, DCC, DUSP6, FOXP1, FOXP2, MEF2C, PCDH7, SEMA6D, SORCS3, and ST3GAL3 ...
Hirlesson Paixão de Matos   +11 more
wiley   +1 more source

African ancestry-enriched variants in the GATM gene are associated with elevated serum creatinine levels

open access: yesGenome Medicine
Background Serum creatinine (Scr) levels are routinely used to estimate kidney function and health. Individuals of African ancestry have higher Scr levels – controlling for differences in age, sex, size, kidney function, and disease status – compared to ...
Shivam Sharma   +3 more
doaj   +1 more source

DeepGenomeScan: A Deep Learning Approach for Whole Genome Scan (WGS) and Genome-wide Association Studies (GWAS)

open access: yes, 2020
DeepGenomeScan: A Deep Learning Approach for Whole Genome Scan (WGS) and Genome-wide Association Studies ...
Xinghu Qin
core   +1 more source

Home - About - Disclaimer - Privacy