Genome-wide association study gwas

Results 11 to 20 of about 115,835 (257)

Transcriptome-wide association study identified candidate genes associated with gut microbiota

Gut Pathogens, 2021
Background Gut microbiota is closely associated with host health and disease occurrence. Host genetic factor plays an important role in shaping gut microbial communities.
Chuyu Pan +12 more
doaj +1 more source

Sequencing-based genome-wide association studies reporting standards

Cell Genomics, 2021
Summary: Genome sequencing has recently become a viable genotyping technology for use in genome-wide association studies (GWASs), offering the potential to analyze a broader range of genome-wide variation, including rare variants.
Aoife McMahon +9 more
doaj +1 more source

Genome wide association study for growth in Pakistani dromedary camels using genotyping-by-sequencing [PDF]

Animal Bioscience, 2023
Objective Growth performance and growth-related traits have a crucial role in livestock due to their influence on productivity. This genome-wide association study (GWAS) in Pakistani dromedary camels was conducted to identify single nucleotide ...
Sajida Sabahat +4 more
doaj +1 more source

Single-step genome-wide association study for susceptibility to Teratosphaeria nubilosa and precocity of vegetative phase change in Eucalyptus globulus

Frontiers in Plant Science, 2023
IntroductionMycosphaerella leaf disease (MLD) is one of the most prevalent foliar diseases of Eucalyptus globulus plantations around the world. Since resistance management strategies have not been effective in commercial plantations, breeding to develop ...
Marianella Quezada +5 more
doaj +1 more source

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Genome Biology, 2022
Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering
Stavroula Kanoni +538 more
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Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci

Breast Cancer Research, 2022
Background Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with breast cancer risk. Twin studies suggest that MD phenotypes are highly heritable. However,
Hongjie Chen +56 more
doaj +1 more source

Integrating Transcriptome-Wide Association Study and mRNA Expression Profiling Identifies Novel Genes Associated With Osteonecrosis of the Femoral Head

Frontiers in Genetics, 2021
ObjectiveThis study aims to identify novel candidate genes associated with osteonecrosis of the femoral head (ONFH).MethodsA transcriptome-wide association study (TWAS) was performed by integrating the genome-wide association study dataset of ...
Mei Ma +10 more
doaj +1 more source

A Genome-Wide Association Study (GWAS) for Bronchopulmonary Dysplasia [PDF]

Pediatrics, 2013
OBJECTIVE: Twin studies suggest that heritability of moderate-severe bronchopulmonary dysplasia (BPD) is 53% to 79%, we conducted a genome-wide association study (GWAS) to identify genetic variants associated with the risk for BPD.
Wang, Hui +12 more
openaire +5 more sources

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

Arthritis Research & Therapy, 2021
Objective To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. Methods A transcriptome-wide association study (TWAS) was conducted by
Cuiyan Wu +11 more
doaj +1 more source

Genetic Predisposition to Neuroblastoma

Children, 2018
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj +1 more source

genome-wide association study
3. good health
humans

gwas
polymorphism, single nucleotide
genotype

genetics
genetic predisposition to disease
transcriptome-wide association study twas