Results 41 to 50 of about 42,338,399 (265)
Precision Medicine Needs to Think Outside the Box
Frontiers in Genetics, 2022 Precision medicine offers a precious opportunity to change clinical practice and disrupt medicine’s reliance on crude racial, ethnic, or ancestral categories by focusing on an individual’s unique genetic, environmental, and lifestyle characteristics ...Daphne O. Martschenko, Jennifer L. Young, Jennifer L. Young +2 moredoaj +1 more sourceDeep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis [PDF]
, 2013 Genome-wide association studies and follow-up meta-analyses in Crohn's disease (CD) and ulcerative colitis (UC) have recently identified 163 disease-associated loci that meet genome-wide significance for these two inflammatory bowel diseases (IBD). These Vermeire, S, Richard H. Duerr (107855), Steve R. Brant, Barclay, M, Sharma, Y., Alikashani, Azadeh, Rutgeerts, P, Colombel, JF, Philippe Goyette, Franke, Andre,, Gautam Goel (457889), Sharma, Yashoda,, Targan, SR, Bresso, Francesca,, Lawrance, I, Ken Sin Lo (457887), Xavier, Ramnik, Jonas Halfvarson, Levine, A, International IBD Genetics Consortium, [missing], McGovern, Dermot P. B., Lo, KS, Regueiro, M, Ellinghaus, David, Stevens, Christine,, International IBD Genetics Consortium, Ahmad, T, D'Inca, R, Bitton, A., Ramnik J. Xavier (153776), Sharma, Y, Lo, K.S., International, I.B.D.G.C., Judy H Cho, Silverberg, MS, Franke, A., Beaudoin, Melissa,, Goel, G, Griffiths, AM, Törkvist, L, Quebec IBD Genetics Consortium, [missing], Azadeh Alikashani (457888), Caroline Lagacé, Weersma, Rinse K., D'Amato, M., Glas, J, Sharma, Yashoda, Weersma, Rinse K.,, Philip L Schumm, Lettre, G., Mowat, Craig; id_orcid, Panés, J, Gautam Goel, Ellinghaus, D., Stevens, C., Beaudoin, Melissa, Jostins, L, Vermeire, S., Guthery, SL, Annese, V, Bis, JC, Lettre, Guillaume, Mélissa Beaudoin, Radford-Smith, G., Azadeh Alikashani, Duerr, RH, Lagacé, C, Boucher, Gabrielle,, Radford-Smith, GL, Newman, W, Florin, T, Phillips, A, Philip L. Schumm (457892), Guillaume Lettre (163230), Weersma, R.K., Gearry, R, Goyette, P., van Gossum, A, Rioux, J.D., Silverberg, Mark S., Lee, J, Vermeire, Severine, Franchimont, Denis, Yashoda Sharma, Mark S Silverberg, Goel, Gautam,, Mauro D'Amato (191109), Daly, Mark J.,, Georges, M, Latiano, A, Duerr, R.H., Proctor, DD, Quebec IBD Genetics Consortium, Duerr, Richard H., Begun, Jakob,, Schreiber, Stefan, John D Rioux, Stevens, Christine, Bresso, F, Cho, Judy H., Schreiber, S., Leif Törkvist (191104), Rivas, M. A., Severine Vermeire, McGovern, D.P.B., Weersma, Rinse K.; id_orcid, Ladouceur, Martin,, Mitrovic, M, Halfvarson, J., Laukens, D, Brant, Steve R., Halfvarson, J, Halfvarson, Jonas, David Ellinghaus (87596), ?, ?, Yashoda Sharma (362205), , K.S. lo, Parkes, M, Mark J Daly, Vito Annese (212128), Lo, Ken Sin,, Rioux, JD, Guillaume Lettre, Manuel A. Rivas, Philip L. Schumm, Goyette, P, Silverberg, M.S., et al., Schumm, PL, Bitton, Alain, Goel, G., Brand, S, Xavier, Ramnik J.,, Christine Stevens (401796), John D. Rioux, Aumais, G, Martin Ladouceur (144366), Cohen, A, Van Gossum, André, Rivas, M.A., Cho, JH, Rivas, Manuel A.,, Cottone, M, Steve R Brant, Ramnik J Xavier, Schumm, Philip L.,, Ken Sin Lo, Cho, Judy H.,, Palmieri, O, Jakob Begun, Gabrielle Boucher, Xavier, R.J., Christine Stevens, Lettre, G, Halfvarson, Jonas,, Brant, S.R., McGovern, Dermot P. B.,, Daly, Mark J., Manuel A Rivas, Potocnik, U, Stevens, C, Begun, J., Philippe Goyette (215465), Ladouceur, M, Bitton, Alain,, Silverberg, Mark S.,, Dermot P B McGovern, McGovern, DPB, Lo, Ken Sin, Alain Bitton (259250), Balschun, T, Prescott, NJ, Boucher, Gabrielle, Anderson, CA, Bresso, F., Schreiber, S, Annese, Vito,, Lo, K. S., International IBD Genetics Consortium,, Schreiber, Stefan,, Francesca Bresso, Mark S. Silverberg, Montgomery, GW, Ladouceur, M., Lees, CW, David Ellinghaus, Mansfield, JC, Mathew, CG, Judy H. Cho, Kugathasan, S, Caroline Lagacé (215515), Franke, Andre, Satsangi, Jack, Weersma, RK, Bresso, Francesca, Mauro D'Amato, Ellinghaus, D, John D. Rioux (215621), McGovern, D.P., Lagace, C., D'Amato, Mauro, Lemann, M, Franke, A, Gabrielle Boucher (215508), Alikashani, Azadeh,, Begun, Jakob, Graham Radford-Smith, Lettre, Guillaume,, Leif Törkvist, Alain Bitton, Mark J. Daly, Deslandres, C, Mowat, C, Steinhart, AH, NIDDK IBD Genetics Consortium, [missing], Xavier, RJ, Boucher, G, Libioulle, C, Lees, Charlie, Rinse K. Weersma (131692), Richard H Duerr, Schumm, P.L., Ellinghaus, David,, Judy H. Cho (159806), Goel, Gautam, Martin Ladouceur, Kullak-Ublick, G, Törkvist, Leif,, Vito Annese, Lagace, Caroline,, D'Amato, Mauro,, Jakob Begun (273749), Begun, J, Alikashani, A., Annese, Vito, Brant, Steve R.,, Int IBD Genetics Consortium, Ponsioen, CY, Ladouceur, Martin, Graham Radford-Smith (457891), Radford-Smith, Graham L., Duerr, Richard H.,, Daly, M.J., Beaudoin, M., Goyette, Philippe, Torkvist, L., Lahaie, R, Dermot P. B. McGovern (179863), Rivas, Manuel A., Brant, SR, Edwards, C, Bayless, TM, Hakonarson, H, Ramnik J. Xavier, Gibson, Greg, Stefan Schreiber, Radford-Smith, Graham,, Louis, E, Mark S. Silverberg (179888), Annese, V., Beaudoin, M, Bernard, EJ, de Jong, DJ, Rivas, MA, Buning, C, Jong, D.J. de, Manuel A. Rivas (228371), Dermot P. B. McGovern, Haritunians, T, Goyette, Philippe,, Consortium, N.I.G., Rinse K. Weersma, Cho, J.H., Baldassano, RN, Mark J. Daly (210204), Andre Franke (77511), Lagace, Caroline, Denson, T, Franchimont, D, Mélissa Beaudoin (457886), NIDDK IBD Genetics Consortium, Alikashani, A, Boucher, G., D'Amato, M, Hugot, JP, Bitton, A, Severine Vermeire (5649814), Schumm, Philip L., Barrett, JC, Richard H. Duerr, Quebec, I.B.D.G.C., Rioux, John D., Steve R. Brant (457890), Andre Franke, Dubinsky, M, Stefan Schreiber (36915), Laukens, Debby, Daly, MJ, Bumpstead, S, Francesca Bresso (191101), Rinse K Weersma, Xavier, Ramnik J., Daly, Mark, Torkvist, Leif, Jonas Halfvarson (117749), Radford-Smith, Graham, Paré, P, Rioux, John D.,, Vermeire, Severine,, Lo K. S., Duerr R. H., Schreiber S., Franke A., Bernard E. -J., Bayless T. M., Targan S. R., Barrett J. C., Torkvist L., Glas J., Panes J., McGovern D. P. B., Buning C., Franchimont D., Haritunians T., Lagace C., Pare P., Silverberg M. S., Rutgeerts P., Halfvarson J., Bitton A., Lee J., Xavier R. J., Roberts R., Simms L. A., Ponsioen C. Y., Satsangi J., Parkes M., Mitrovic M., Hakonarson H., Proctor D. D., Potocnik U., D'Inca R., de Jong D. J., Verspaget H. W., Gearry R., Palmieri O., Phillips A., Weersma R. K., Florin T., Latiano A., Hugot J. -P., Cho J. H., Seibold F., Goel G., Beaudoin M., Balschun T., Cohen A., Rivas M. A., D'Amato M., Jostins L., Prescott N. J., Lawrance I., Kugathasan S., Dubinsky M., Whiteman D., Ladouceur M., Barclay M., Steinhart A. H., Regueiro M., Montgomery G. W., Sans M., Cottone M., Wang K., Ellinghaus D., Deslandres C., Libioulle C., Sanderson J., Laukens D., Radford-Smith G. L., Baldassano R. N., Denson T., Mowat C., Guthery S. L., Alikashani A., Lahaie R., Sharma Y., Georges M., Schumm P. L., Taylor K. D., Walters T., Lemann M., Bumpstead S., Edwards C., Vermeire S., Ahmad T., Annese V., Bresso F., Mansfield J. C., Louis E., Lees C. W., Levine A., Daly M. J., Aumais G., de Vos M., Anderson C. A., Griffiths A. M., van Gossum A., Begun J., Lettre G., Newman W., Wijmenga C., Rioux J. D., Mathew C. G., Rotter J. I., Bis J. C., Brand S., Colombel J. -F., Brant S. R., Stevens C., Goyette P., Boucher G., Kullak-Ublick G. +421 morecore +1 more sourceA genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium [PDF]
, 2011 Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease.Marsit CJ, Carmen J. Marsit, Oszutowska, Dorota, McLaughlin, John, Hung, Rayjean J, Fish Sherianne, Romkes Marjorie, Key, Timothy, Trichopoulos D, Lacko, Martin, Panico, S, González, C.A., Riboli, E., Oszutowska D, Arzani, Dario, Foglio, Mario, Hayes, Richard B, Schwartz SM, Wilbert H. M. Peters, Hashibe Mia, Tumino R, Dario Arzani, Key Timothy, Szeszenia-Dabrowska, Neonila, Stephen M Schwartz, Vineis P, Zhang Zuo-Feng, McLaughlin J, Lathrop, Mark, Trubicka Joanna, Brennan P., Lorenzo Richiardi, Chabrier, Amelie, Krogh, Vittorio, Chuang, S-C, Boffetta Paolo, Peters, Wilbert HM, Manni, Johannes J, Jingchun Luo, Liloglou T, Heath, S, Shama Buch, Bencko, V, Trichopoulos Dimitrios, Domenico Palli, Khaw KT, Luo, J., Voodern, T., Funkhouser WK, Macfarlane, Tatiana V, Field, John K, Wei Q, Doody David R., McClean Michael D., Herrero, R, Peters, W.H.M., Arzani, D, Macfarlane, TV, Njolstad, I., Quirós JR, Trichopoulou, A., Välk, K., Luo, Jingchun, Zhang, Z.F., Marsit, Carmen J., Martıínez, Carmen, Gaborieau Valerie, Boccia Stefania, H Bas Bueno-de-Mesquita, Hallmans, Göran, Alexandru Bucur, Conway, D. I., Blanché, H., Amelie Chabrier, Menezes, Ana, Lagiou, Pagona, Castellsagué, X, Tumino, R., Menezes Ana, José Eluf Neto, Neto JE, Koifman Sergio, Lagiou, P., McKay JD, Peters, W.H., Luo, JC, Riboli, Elio, Garrote LF, Tumino, Rosario, Fabianova, Eleonora, Conway, David I., Chen C, Luo Jingchun, Manni, Johannes J., Wünsch Filho V, Sturgis EM, Andres Metspalu, Heather H. Nelson, Ardanaz, Eva, Kumle, Merethe, Gary J. Macfarlane, et al., Gut, Ivo G., Therese Truong, -, Philip Lazarus, Navarro Carmen, Chabrier, A, Ivo G. Gut, Vatten, Lars Johan, Liloglou, T, John K Field, Benhamou Simone, Chabrier A, Bueno de Mesquita, H. Bas, Krogh V, Hashibe, M., Chabrier, A., Szeszenia-Dabrowska Neonila, Marsit, CJ, Overvad, Kim, Johannes J. Manni, Peters, W. H. M., Hung, Rayjean J., Funkhouser William K., Doody, DR., Clavel-Chapelon, F., Palli, D., Navarro, Carmen, Gallagher Carla J., Marsit Carmen J., Muscat, JE, Trubicka J, Eleonora Fabianova, John K. Field, Bueno-de-Mesquita, HB, Antonia Trichopoulou, Njølstad, I, Ahrens Wolfgang, Neto, J.E., Pagona Lagiou, Wei Qingyi, Gary E. Goodman, Shen-Chih Chang, Heath, S., Herrero Rolando, Clavel Chapelon F, Peeters, Petra H M, Talamini, R, McClean MD, McLaughlin John, Kelsey, Karl T., Heath Simon, Galan, P., Vineis, P., Goodman, G.E., Chuang, S.-C., Kumle, M., Bucur Alexandru, Peeters, Petra H. M., Carmen Navarro, H. Bas Bueno-de-Mesquita, Ardanaz, E, Quirós, José Ramón, Peters, Wilbert H. M, Galan P, Hung, RJ, Gary E Goodman, Wünsch-Filho, V, Zhang, ZF, Muscat JE, Holcatova, Ivana, Tjønneland, Anne, Gallagher, Carla J., Francoise Clavel-Chapelon, Chang, SC, Byrnes G, Navarro, C., Galan Pilar, Doody, D.R., Goodman, Gary E, Gaborieau, V, Nukui, Tomoko, Lathrop Mark, Fabianova E, Olshan, Andrew F, Marjorie Romkes, David R. Doody, Tõnu Voodern, González, CA, Trichopoulou A, Bouchardy, C., Schwartz, Stephen M, Toner, ME, Wuensch-Filho, V, Gut IG, Dimitrios Trichopoulos, Kjaerheim, K., Bucur, A, Vooder T, Castellsagué X, Trichopoulos, D., Peeters, P.H., Simonato, Lorenzo, Nelson, HH, Olshan AF, Therese Truong,, Delepine, Marc, Wolfgang Ahrens, Chang, S-C, Franceschi, S., Brennan, P, Bocciai, Stefania, Curado, M. P., Hayes, Richard B., Joshua E Muscat, Peters WH, Ramon Quiros, J., Zhong Shilong, Hayes, RB, Schwartz, Stephen M., Schwartz, SM, Gallagher CJ, Heather H Nelson, Garrote, L.F., Macfarlane, Tatiana V., Quirós J. Ramón, Galan, P, William K. Funkhouser, Weissler, MC, Carlos A. González, Cadoni, G, Anne Boland, Chang SC, Palli, Domenico, Therese Truong, Curado MP, McClean, MD, McKay James D., Macfarlane TV, Välk Kristjan, Marsit, C.J., Antonio Agudo, Overvad, K., Wünsch-Filho, Victor, Talamini R, Linseisen, Jakob, Zaridze David, Lenka Foretova, Bueno-de-Mesquita, H.B., Peeters, P. H. M., Neto, José Eluf, Wünsch-Filho, V., Larrañaga N, Sturgis, E.M., Patricia A. McKinney, Carmen Martínez, Kelsey, KT, Michael D. McClean, Lubiński, J., Delepine, M, Bueno-de-Mesquita H. Bas, Karl T. Kelsey, Overvad K, Oszutowska, D, Claire M Healy, MacFarlane, Tatiana, Ariana Znaor, Neonila Szeszenia-Dabrowska, Castellsagué, Xavier, Tatiana V Macfarlane, Zhang ZF, Wei, Q, Khaw, KT, Quirós, J.R., Funkhouser, WK, Truong, T., Chuang, S. -C., Bueno de Mesquita HB, Simonato, L, Curado, Maria Paula, Weissler Mark C., Chuang, Shu-Chun, Lathrop, M, Doris Lechner, Valk, K, Heath, Simon C., Marsit, Carmen J, Romkes M, Linseisen Jakob, Martínez C, Hung, R.J., Gut, I.G., Wang LE, Lazarus P, Zelenika, D, Romkes, Marjorie, Trichopoulou, Antonia, Agudo Antonio, Linseisen, J., Musca, Joshua E., Hayes RB, Chang, S.C., Jakob Linseisen, William K Funkhouser, Chen Chu, Brennan, P., Field, John K., Palli D, Gallagher, C. J., Macfarlane, GJ, Vatten L, Erich M Sturgis, Larrañaga Nerea, Kristina Kjaerheim, Carla J Gallagher, Shangina, O., Manni, JJ, Conway, D.I., Stefania Boccia, Zhong, S., Navarro C, Quirós, J. R., Krogh, V, Bouchardy C, Overvad, K, Key T, Simonato Lorenzo, Lechner D, Chabrier Amelie, Oxana Shangina, McClean, Michael D., Foglio, M., Boffetta, Paolo, Luo J, Zhong, SL, Sturgis, EM, Larrañaga, N., Fernandez Garrote, L, Key, T, Weissler, Mark C., Key, T., Zhong, Shilong, Lechner, D., Hallmans Göran, Kelsey, K. T., Palli, D, Agudo, Antonio, Healy Claire M., Khaw, Kay-Tee, Linseisen J, McKay, JD, Bueno-de-Mesquita, H Bas, Janout, V, Voodern Tõnu, Bouchardy Christine, Doody, David R., Christine Bouchardy, Weissler, M. C., Macfarlane, Gary J., Olshan, A.F., Lorenzo Simonato, Manni, J. J., Richard B. Hayes, Vatten, L, Vladimir Bencko, Vatten, L., Horwitz, Marshall S., Shangina Oxana, Doody, DR, Kristjan Välk, Fish, S, Joshua E. Muscat, Bueno-de-Mesquita, Bas, Ardanaz, E., Kumle M, Kumle Merethe, Bencko, V., Zelenika, Diana, Chang Shen-Chih, Peeters, Petra HM, Castellsagué, X., Clavel-Chapelon Francoise, Manni Johannes J., Clavel-Chapelon, Francoise, Koifman S, Tjønneland, A., Eva Ardanaz, Wang, Li-E., Rudnai, Peter, Nerea Larrañaga, Fernandez Garrote, Leticia, Overvad Kim, Goodman, G. E., Simonato L, Blanche´, Hélène, Zhang, Z. -F., INHANCE Consortium, Ahrens, Wolfgang, Cadoni, Gabriella, Göran Hallmans, Talamini Renato, McLaughin, John, Szeszenia-Dabrowska, N., Curado, M.P., Menezes, A, Carlos A González, Holcatova, I., Merethe Kumle, Schwartz, S.M., Znaor, Ariana, Olshan, Andrew F., Lubiński, J, David I. Conway, Martínez, C, McLaughlin, John R., Macfarlane, G.J., Hayes, R. B., Benhamou S, Doody DR, Hallmans G, Truong Therese, Cadoni Gabriella, Neto, J. E., Lener, M., Boffetta, P., Field, J.K., Hayes, R.B., Merletti, F, Krogh Vittorio, Canova, Cristina, McKay, James D., Salvatore Panico, Healy, C. M., McKinney, PA, Weissler, Mark C, Zaridze, D., Byrnes, G, Conway, David I, Szeszenia Dabrowska N, Larrañaga, N, Brennan Paul, Foretova L, Ramon Quiros, J, McKinney, P.A., Sturgis, E. M., Tatiana V. Macfarlane, Muscat, Joshua E., Chuang Shu-Chun, Luo, J, J. Ramón Quirós, McKinney PA, Lacko Martin, Richard B Hayes, Canova, C., Zaridze, David, James D McKay, Rayjean J. Hung, Macfarlane, T. V., Boeing, H., Rudnai, P., Claire M. Healy, Paolo Vineis, Trubicka, J, Kjaerheim Kristina, Zhang, Zuo-Feng, Weissler, M.C., Trubicka, Joanna, Välk, Kristjan, Victor Wünsch-Filho, Foretova, L., Wang, L-E, McLaughlin, J., Lagiou, P, Martínez, C., Wei, QY, Znaor Ariana, Gaborieau, V., Graham Byrnes, Benhamou, Simone, Heath S, Boccia S, Wang, Li-E, David Zaridze, Cadoni G, Hallmans, G, Janout V, Barzan L, Macfarlane, G. J., Njølstad, Inger, Timothy Key, McClean, M.D., Silvia Franceschi, Boland A, David I Conway, Lars Vatten, Peter Rudnai, Nelson HH, Wei, Q., Qingyi Wei, Zaridze, D, Znaor A, McClean, M. D., Clavel-Chapelon, F, J Ramón Quirós, Nukui, T, Franceschi, S, McKinney Patricia A., Blanche, H, Tõnu Vooder, Garrote, L. F., Panico Salvatore, Bucur, A., Trubicka, J., Boland, A., Shangina O, Nelson, Heather H., Garrote, LF, Menezes, Ana A., Muscat, Joshua E, Li-E Wang, Vineis, Paolo, Sherianne Fish, Mark C. Weissler, Valerie Gaborieau, Zhong, S, Vaelk, Kristjan, Bueno-de-Mesquita, H. B., Peters Wilbert H. M., Riboli, E, Mary E Toner, Wang, LE, Gut Ivo G., Chuang, SC, Macfarlane Tatiana V., Andrew F. Olshan, Muscat Joshua E., Goodman, GE, Chuang SC, Toner, Mary E., González, C. A., Välk K, Mark Lathrop, Nukui T, Jan Lubiński, Macfarlane, TV., Franceschi, Silvia, Boffetta, P, Lazarus, P., Hélène Blanché, Toner, Mary E, Metspalu Andres, Zelenika Diana, Vatten Lars, Peeters Petra H. M., Toner Mary E., Funkhouser, William K, Lechner, D, Barzan Luigi, James D. McKay, Curado Maria Paula, Mario Foglio, Blanché, Hélène, McKinney, Patricia A., Ahrens, W, Petra H M Peeters, Romkes, M, Lathrop M, Wei, Qingyi, Conway David I., Goodman, Gary E., Chen, Chu, Fish, Sherianne, Hashibe, M, Key, Timothy J., Heiner Boeing, Njølstad Inger, Kelsey, K.T., Richiardi Lorenzo, Rudnai, P, Nelson Heather H., Delepine Marc, Fish, S., Foglio M, Shangina, O, Quirós, JR, Zuo-Feng Zhang, Healy, C.M., Simon Heath, Byrnes, Graham, McKinney, Patricia A, Hashibe M, Khaw Kay-Tee, Elio Riboli, Carla J. Gallagher, Boeing, H, Franceschi S, Lazarus, Philip, Manni, J.J., Njolstad, Inger, Liloglou, T., Bucur A, Kelsey, Karl T, Lissowska, J, Lowry R, Arzani, D., Koifman, Sergio, Trichopoulou, A, Benhamou, S, Fabianova, E., Buch S, Vooder, T., Arzani Dario, Lacko M, Boland Anne, Martin Lacko, Menezes, Ana M., Oszutowska, D., Andrew F Olshan, Peeters PH, Ahrens W, Castellsagué Xavier, Macfarlane GJ, Merletti F, Healy, Claire M, Byrnes Graham, Lissowska Jolanta, Boland, Anne, Healy, Claire M., Lagiou P, McKinney, P. A., Doody, D. R., Kim Overvad, Menezes, A., Martínez Carmen, Gallagher, C.J., Herrero, R., Carmen J Marsit, Barzan, L., Wang, L. -E., Barzan, L, Toner, M. E., Kjaerheim, K, Wünsch-Filho Victor, Gallagher, Carla J, Vooder, Tõnu, Boccia, S., González CA, Rolando Herrero, González Carlos A., Fabianova Eleonora, Paul Brennan, Foretova, L, Bencko V, McKay, J.D., Vineis Paolo, Trichopoulos, Dimitrios, Boccia, Stefania, Liloglou, Triantafillos; id_orcid, Chen, C, Quirós, J Ramón, Lacko, M, Fish S, Macfarlane, G, Lowry Ray, Sturgis, Erich M, Holcatova Ivana, Doody, David R, Riboli Elio, Brennan, Paul, Peeters, PHM, Tjonneland, A, Voodern, T, Tumino, R, Vineis, P, Liloglou Triantafillos, Trichopoulou Antonia, Macfarlane, T.V., Heath, Simon, Toner, M.E., Weissler MC, Ahrens, W., Hayes Richard B., Peeters, P.H.M., Tjønneland Anne, Hayes, RB., Tumino Rosario, Paolo Boffetta, Foretova Lenka, Merletti Franco, Koifman, S., Marc Delepine, Lubiński Jan, Njolstad, I, Franco Merletti, Stephen M. Schwartz, Menezes A, Muscat, J.E., Funkhouser, William K., Bencko Vladimir, Conway, DI, Trichopoulos, D, Bueno-de-Mesquita, H. Bas, Richiardi, L, Gallagher, CJ, Field, J. K., Lacko, M., Vittorio Krogh, Buch Shama, Fabianova, E, Zaridze D, Arzani D, Agudo, A., Rudnai P, Lazarus, P, Panico, Salvatore, Field JK, Kjaerheim, Kristina, Gut, IG, Erich M. Sturgis, Merletti, F., Karl T Kelsey, David R Doody, Mia Hashibe, Boeing Heiner, Zhang, Z-F, McKay, James D, Funkhouser, W.K., Hung RJ, Rudnai Peter, Janout, V., Canova, C, Linseisen, J, Kelsey Karl T., Macfarlane, Gary J, Peters, Wilbert H.M., Lissowska, J., Chen, C., Schwartz Stephen M., Lubiński J, Muscat, J. E., Martínez, Carmen, Buch, Shama, Curado, MP, Njølstad I, Funkhouser, W. K., Kjærheim, Kristina, Truong, Therese, Blanché Hélène, Bucur, Alexandru, Canova C, Chu Chen, Peters, Wilbert H. M., Lener, Marcin, Kay-Tee Khaw, Krogh, V., Khaw, K-T, Herrero, Rolando, Hung Rayjean J., Delepine M, Xavier Castellsagué, Petra H. M. Peeters, Joanna Trubicka, Peters, WHM, Holcatova I, Delepine, M., González, Carlos A, Talamini, R., Healy, CM, Richiardi, Lorenzo, Quirós, J. Ramón, Panico, S., Macfarlane Gary J., Kjaerheim K, Simone Benhamou, Jolanta Lissowska, Healy CM, Byrnes, G., Goodman GE, Peters, Wilbert H M, Foglio Mario, Oszutowska Dorota, Kumle, M, Lowry, R., Gabriella Cadoni, Benhamou, S., Zhong S, Field John K., Cadoni, G., Richiardi, L., John McLaughlin, Chang, Shen-Chih, Buch, S., Boeing H, Lener Marcin, Metspalu, A., Blanché H, Conway, DI., Neto, JE, McLaughlin, J, Maria Paula Curado, Lowry, Ray, Hallmans, G., Wuensch-Filho, Victor, Neto José Eluf, Buch, S, Merletti, Franco, Metspalu A, Metspalu, A, Ray Lowry, Ardanaz E, Znaor, A, Garrote Leticia Fernández, Lechner, Doris, Sergio Koifman, Lissowska J, Boeing, Heiner, Herrero R, Tjonneland, Anne, Shu-Chun Chuang, Marcin Lener, Macfarlane, GJ., McKay, J. D., Romkes, M., Therese, T, Gary J Macfarlane, Gut, I. G., Liloglou, Triantafillos, Mary E. Toner, Rayjean J Hung, Conway DI, Vatten, Lars, Manni JJ, Khaw, K.T., Palli Domenico, Dorota Oszutowska, Shangina, Oxana, Lowry, R, Olshan, AF, Truong T, Lathrop, M., Vladimir Janout, Chuang, S.C., Nukui, T., Field, JK, Luigi Barzan, Rosario Tumino, Gaborieau V, Ivo G Gut, McClean, Michael D, Lechner Doris, Goodman Gary E., Szeszenia-Dabrowska, N, Riboli E, Hallmans, Göran,, Boland, A, Znaor, A., Njølstad, I., Nelson, H.H., Franceschi Silvia, Schwartz, S. M., Zelenika, D., Olshan Andrew F., Janout Vladimir, Zelenika D, Inger Njølstad, Olshan, A. F., Shilong Zhong, Khaw, K. -T., Koifman, S, Renato Talamini, Anne Tjønneland, Agudo, A, Kelsey KT, Wang, L.E., Agudo A, Lazarus Philip, Lagiou Pagona, Lener, M, Nelson, Heather H, Cristina Canova, Chang, S. -C., Janout, Vladimir, Gut, Ivo G, Horwitz, M.S., Johannes J Manni, Gaborieau, Valerie, Bouchardy, Christine, Nukui Tomoko, Leticia Fernández Garrote, Bouchardy, C, Navarro, C, Simonato, L., Ivana Holcatova, Triantafillos Liloglou, Toner ME, Boffetta P, Tjønneland A, Talamini, Renato, Mark C Weissler, Holcatova, I, Tomoko Nukui, Barzan, Luigi, Bencko, Vladimir, Hashibe, Mia, Michael D McClean, Truong, T, Lissowska, Jolanta, Canova Cristina, Wang Li-E, Pilar Galan, Marsit, C. J., Vaelk, K, Patricia A McKinney, Garrote, Leticia Fernández, Wilbert H M Peters, Ardanaz Eva, Foglio, M, Ana Menezes, Hung, R. J., Sturgis Erich M., Galan, Pilar, Diana Zelenika, Nelson, H. H., Boccia, S, Foretova, Lenka, Richiardi L, Sturgis, Erich M., Metspalu, Andres, Lener M, Voodern, Tõnu, ELUF NETO, Jose, Gonzalez, Carlos A., Larrañaga, Nerea, Lubiński, Jan +933 morecore +1 more sourceImproved heritability estimation from genome-wide SNPs [PDF]
, 2012 Narrow-sense heritability (h(2)) is an important genetic parameter that quantifies the proportion of phenotypic variance in a trait attributable to the additive genetic variation generated by all causal variants.Johnson, Michael R., Balding, DJ, Hemani, G, Hemani, Gibran, Balding, David J., Speed, D, Johnson, MR, Speed, Doug +7 morecore +1 more sourceCerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods
In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao +13 morewiley +1 more sourceIntegrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries
Advanced Science, EarlyView.The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu +27 morewiley +1 more source
