Frontiers in Plant Science, 2023 IntroductionIsoflavones are the secondary metabolites synthesized by the phenylpropanoid biosynthesis pathway in soybean that benefits human and plant health.MethodsIn this study, we have profiled seed isoflavone content by HPLC in 1551 soybean ...
Muhammad Azam +10 more
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Genomic factors underlying sex differences in trauma-related disorders
Neurobiology of Stress, 2021 Post-traumatic stress disorder (PTSD) is a devastating illness with treatment that is effective in only approximately half of the population. This limited rate of response highlights the necessity for research into underlying individual biological ...
Olga Y. Ponomareva, Kerry J. Ressler
doaj +1 more source
Elevated polygenic burden for autism is associated with differential DNA methylation at birth
Genome Medicine, 2018 Background Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities.
Eilis Hannon +22 more
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A foundation for provitamin A biofortification of maize: genome-wide association and genomic prediction models of carotenoid levels. [PDF]
, 2014 Efforts are underway for development of crops with improved levels of provitamin A carotenoids to help combat dietary vitamin A deficiency. As a global staple crop with considerable variation in kernel carotenoid composition, maize (Zea mays L.) could ...
Buckler, Edward S +13 more
core +1 more source
Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates. [PDF]
, 2020 Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP)
Aldana, Ileana +37 more
core +3 more sources
Genome-wide association analysis to identify QTL for carcass traits in Hanwoo (Korean native cattle)
Indian Journal of Animal Sciences, 2019 A genome-wide association study (GWAS) was performed to investigate the genetic markers associated with carcass traits of Hanwoo (Bos taurus coreanae) steer in the Gangwon region of Korea.
MIN-WOOK HONG +7 more
doaj +1 more source
The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]
, 2013 Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel +12 more
core +2 more sources
Genetic dissection of photoperiod response based on GWAS of pre-anthesis phase duration in spring barley [PDF]
, 2014 Heading time is a complex trait, and natural variation in photoperiod responses is a major factor controlling time to heading, adaptation and grain yield.
A Tondelli +51 more
core +19 more sources
Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction
BMC Research Notes, 2023 Objective To use genome-wide association study (GWAS) by subtraction, a method for deriving novel GWASs from existing summary statistics, to derive genome-wide summary statistics for paternal smoking.
Benjamin Woolf +3 more
doaj +1 more source
Syringohydromyelia in Dogs: The Genomic Component Underlying a Complex Neurological Disease
Animals, 2022 Syringohydromyelia (SHM) is a neurological disorder characterized by the appearance of fluid-containing cavities within the spinal cord. Although SHM is thought to be under multigenic control, the molecular basis of this disease remains poorly defined. A
Sandra Andrino +5 more
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