Results 21 to 30 of about 115,431 (259)

Genetic Predisposition to Neuroblastoma

open access: yesChildren, 2018
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj   +1 more source

Genome-wide association study comparison analysis based on Hanwoo full-sib family [PDF]

open access: yesAnimal Bioscience
Objective The improvement of carcass traits is essential for the Hanwoo industry because of the Hanwoo grade determination system, and genome-wide association study (GWAS) analysis is an instrumental tool for identifying the genetic factors that impact ...
Ji-Yeong Kim   +5 more
doaj   +1 more source

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

open access: yesGenome Medicine, 2018
Background Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities.
Eilis Hannon   +22 more
doaj   +1 more source

Syringohydromyelia in Dogs: The Genomic Component Underlying a Complex Neurological Disease

open access: yesAnimals, 2022
Syringohydromyelia (SHM) is a neurological disorder characterized by the appearance of fluid-containing cavities within the spinal cord. Although SHM is thought to be under multigenic control, the molecular basis of this disease remains poorly defined. A
Sandra Andrino   +5 more
doaj   +1 more source

Genome-wide association analysis to identify QTL for carcass traits in Hanwoo (Korean native cattle)

open access: yesIndian Journal of Animal Sciences, 2019
A genome-wide association study (GWAS) was performed to investigate the genetic markers associated with carcass traits of Hanwoo (Bos taurus coreanae) steer in the Gangwon region of Korea.
MIN-WOOK HONG   +7 more
doaj   +1 more source

A Review of Prostate Cancer Genome-Wide Association Studies (GWAS) [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2018
Abstract Prostate cancer is the most common cancer in men in Europe and the United States. The genetic heritability of prostate cancer is contributed to by both rarely occurring genetic variants with higher penetrance and moderate to commonly occurring variants conferring lower risks.
Benafif, S   +3 more
openaire   +3 more sources

Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction

open access: yesBMC Research Notes, 2023
Objective To use genome-wide association study (GWAS) by subtraction, a method for deriving novel GWASs from existing summary statistics, to derive genome-wide summary statistics for paternal smoking.
Benjamin Woolf   +3 more
doaj   +1 more source

Identification of hub genes regulating isoflavone accumulation in soybean seeds via GWAS and WGCNA approaches

open access: yesFrontiers in Plant Science, 2023
IntroductionIsoflavones are the secondary metabolites synthesized by the phenylpropanoid biosynthesis pathway in soybean that benefits human and plant health.MethodsIn this study, we have profiled seed isoflavone content by HPLC in 1551 soybean ...
Muhammad Azam   +10 more
doaj   +1 more source

Genome-wide association study reveals a QTL and strong candidate genes for umbilical hernia in pigs on SSC14

open access: yesBMC Genomics, 2018
Background Umbilical hernia is one of the most prevalent congenital defect in pigs, causing economic losses and substantial animal welfare problems. Identification and implementation of genomic regions controlling umbilical hernia in breeding is of great
Eli Grindflek   +3 more
doaj   +1 more source

Genomic factors underlying sex differences in trauma-related disorders

open access: yesNeurobiology of Stress, 2021
Post-traumatic stress disorder (PTSD) is a devastating illness with treatment that is effective in only approximately half of the population. This limited rate of response highlights the necessity for research into underlying individual biological ...
Olga Y. Ponomareva, Kerry J. Ressler
doaj   +1 more source

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