Results 21 to 30 of about 191,340 (203)

Multi-omics integration reveals molecular networks and regulators of psoriasis. [PDF]

, 2019
BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) have been carried out to identify genetic ...
Arneson, Douglas, Jhamb, Deepali, Rajpal, Deepak K, Shu, Le, Yang, Xia, Zhao, Yuqi   +5 more
core   +3 more sources

A Genome-Wide Association Study (GWAS) for Bronchopulmonary Dysplasia [PDF]

Pediatrics, 2013
OBJECTIVE: Twin studies suggest that heritability of moderate-severe bronchopulmonary dysplasia (BPD) is 53% to 79%, we conducted a genome-wide association study (GWAS) to identify genetic variants associated with the risk for BPD.
Wang, Hui, St. Julien, Krystal R, Stevenson, David K, Hoffmann, Thomas J, Witte, John S, Lazzeroni, Laura C, Krasnow, Mark A, Quaintance, Cecele C, Oehlert, John W, Jelliffe-Pawlowski, Laura L, Gould, Jeffrey B, Shaw, Gary M, O’Brodovich, Hugh M   +12 more
openaire   +5 more sources

Genetic Predisposition to Neuroblastoma

Children, 2018
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj   +1 more source

Genome-Wide Association Study in a Lebanese Cohort Confirms PHACTR1 as a Major Determinant of Coronary Artery Stenosis [PDF]

, 2016
The manifestation of coronary artery disease (CAD) follows a well-choreographed series of events that includes damage of arterial endothelial cells and deposition of lipids in the sub-endothelial layers.
Cazier, Jean-Baptiste, Ghassibe-Sabbagh, Michella, Hager, Jörg, Kamatani, Yoichiro, Khazen, Georges, Platt, Daniel E., Youhanna, Sonia, Zalloua, Pierre A.   +7 more
core   +1 more source

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : a report from the COGENT consortium [PDF]

, 2016
CORRIGENDUM Molecular Psychiatry (2017) 22, 1651–1652 http://www.nature.com/articles/mp2017197.pdfThe complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide ...
A C Need, A Christoforou, A Corvin, A Hatzimanolis, A J Lundervold, A K Malhotra, A N Voineskos, A Okbay, A Palotie, A Payton, A R Hariri, A Saito, AE Locke, AJ Myers, AM Bonnet, AP Morris, AR Wood, B Benyamin, B Bulik-Sullivan, B Konte, BK Bulik-Sullivan, BS Pickard, C Dias, C Shaw-Smith, CA de Leeuw, CA Rietveld, CA Rietveld, CC Chang, CF Chabris, CG DeYoung, CJ Willer, CM Calvin, CM Haworth, D Avramopoulos, D C Glahn, D C Liewald, D Dickinson, D Dickinson, D E Arking, D K Attix, D Morris, D R Weinberger, D Rujescu, D Wechsler, D Zimprich, E Congdon, E D Conley, E Knowles, E London, E T Cirulli, E Widen, F Ferreri, F W Sabb, G Davies, G Davies, G Davies, G Davies, G Donohoe, G Marangi, GM Cooper, GTEx Consortium, H Stefansson, HR Snyder, I Giegling, I J Deary, I Melle, I Reinvang, IF Mata, IJ Deary, IJ Deary, IJ Deary, IJ Deary, J G Eriksson, J Lahti, J M Starr, J Pietschnig, J W Trampush, J Yang, J Yu, JB Carroll, JM Halperin, JW Trampush, K E Burdick, K Räikkönen, K Sundet, KB Rajan, KE Burdick, L Sha, L-F Low, M A Scult, M C Keller, M Cruts, M Gill, M Horan, M L Z Yang, M Wainwright, M Ziegler, M Zollino, MA Ikram, MA Nalls, MC Zody, MD Taylor, MJ Hawrylycz, MP Donnelly, MS Panizzon, N A Freimer, N C Stefanis, N Pendleton, N Smyrnis, O A Andreassen, O Chiba-Falek, P Bitsios, P DeRosse, P Loh, P Roussos, PM Visscher, PN Rao, R A Poldrack, R E Straub, R M Bilder, S Djurovic, S Giakoumaki, S Kitsiou-Tzeli, S Le Hellard, S McCarthy, S Zollner, SE Christ, SI Berndt, SP Hagenaars, SV Rakhilin, T Clarke, T D Cannon, T Espeseth, T Lencz, T Lencz, V M Steen, W Johnson, W Ollier, WD Hill   +138 more
core   +10 more sources

Genetic associations with childhood brain growth, defined in two longitudinal cohorts [PDF]

, 2018
Genome-wide association studies (GWASs) are unraveling the genetics of adult brain neuroanatomy as measured by cross-sectional anatomic magnetic resonance imaging (aMRI). However, the genetic mechanisms that shape childhood brain development are, as yet,
Jansen, Philip R., Justice, Cristina M., Muetzel, Ryan L., Sabourin, Jeremy A., Schwantes-An, Tae-Hwi Linus, Sharp, Wendy, Shaw, Philip, Sung, Heejong, Szekely, Eszter, Tiemeier, Henning, White, Tonya J., Wilson, Alexander F.   +11 more
core   +1 more source

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript [PDF]

, 2011
Genome-wide association studies (GWAS) have identified more than 30 prostate cancer (PrCa) susceptibility loci. One of these (rs2735839) is located close to a plausible candidate susceptibility gene, KLK3, which encodes prostate-specific antigen (PSA)
Kote-Jarai, Z., Amin Al Olama, A., Leongamornlert, D., Tymrakiewicz, M., Saunders, E., Guy, M., Giles, Graham, Severi, G., Southey, M., Hopper, J. L., Sit, K. C., Harris, J. M., Batra, J., Spurdle, A. B., Clements, J. A., Hamdy, Freddie C., Neal, David E., Donovan, Jenny, Muir, Kenneth, Pharoah, P. D. P., Chanock, Stephen, Brown, N., Benlloch, S., Castro, E., Mahmud, N., O'Brien, L., Hall, A., Sawyer, E., Wilkinson, R., Easton, Douglas F., Eeles, Rosalind A.   +30 more
core   +2 more sources

Genome-wide association studies in Plasmodium species [PDF]

, 2010
Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be ...
Bridget Penman, Caroline Buckee, Sean Nee, Sunetra Gupta   +3 more
core   +3 more sources

Genome-wide association study comparison analysis based on Hanwoo full-sib family [PDF]

Animal Bioscience
Objective The improvement of carcass traits is essential for the Hanwoo industry because of the Hanwoo grade determination system, and genome-wide association study (GWAS) analysis is an instrumental tool for identifying the genetic factors that impact ...
Ji-Yeong Kim, Eun-Ho Kim, Ho-Chan Kang, Cheol-Hyun Myung, Il-Keun Kong, Hyun-Tae Lim   +5 more
doaj   +1 more source

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation [PDF]

, 2016
We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS) susceptibility in German cohorts with 4888 cases and 10,395 controls. In addition to associations within the major histocompatibility complex (MHC) region, 15 non-MHC loci ...
Andlauer, TF, Antony, G, Arloth, J, Bayas, A, Bechmann, L, Berger, K, Berthele, A, Bertram, L, Bettecken, T, Binder, EB, Buck, D, Carrillo-Roa, T, Chan, A, Cucca, F, Czamara, D, Dankowski, T, Franke, A, Gasperi, C, Gieger, C, Gold, R, Graetz, C, Haas, J, Hecker, M, Hemmer, B, Herms, S, Homuth, G, Infante-Duarte, C, Ising, M, Jöckel, KH, Kacprowski, T, Kloiber, S, Knop, M, Kümpfel, T, Laudes, M, Lichtner, P, Lieb, W, Lill, CM, Limmroth, V, Linker, RA, Loleit, V, Lucae, S, Luessi, F, Meitinger, T, Meuth, SG, Moebus, S, Mulas, A, Mühlau, M, Müller-Myhsok, B, Müller-Nurasyid, M, Nischwitz, S, Nöthen, MM, Paul, F, Petersmann, A, Pitzalis, M, Porcu, E, Pütz, M, Radivojkov-Blagojevic, M, Rawal, R, Ruck, T, Salmen, A, Scheinhardt, MO, Schminke, U, Sidore, C, Stangel, M, Stellmann, JP, Strauch, K, Stürner, KH, Tackenberg, B, Then Bergh, F, Tumani, H, Völzke, H, Waldenberger, M, Warnke, C, Weber, F, Weber, P, Wellmann, J, Wiendl, H, Wildemann, B, Zara, I, Zettl, UK, Ziegler, A, Ziemann, U, Zipp, F, Zoledziewska, M   +83 more
core   +2 more sources