Results 21 to 30 of about 42,338,399 (265)

Genome-wide association study of receptive language ability of 12 year olds [PDF]

open access: yes, 2013
Purpose: We have previously shown that individual differences in measures of receptive language ability at age 12 are highly heritable. The current study attempted to identify some of the genes responsible for the heritability of receptive language ...
Hanscombe, K.B.   +32 more
core   +1 more source

Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci [PDF]

open access: yes, 2013
Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker of body fat distribution. Although obesity disproportionately affects minority populations, few studies have conducted genome-wide association study (GWAS) of fat
Burke, Gregory L.   +431 more
core   +1 more source

A genome-wide association search for type 2 diabetes genes in African Americans [PDF]

open access: yes, 2011
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity.
Bostrom, Meredith A   +999 more
core   +2 more sources

Genome-wide Association Study of Cancer Risk in UK Biobank [PDF]

open access: yes, 2021
This deposit provides full details of the genome-wide association study (GWAS) of pan-cancer and site-specific cancers in UK Biobank participants. For any issues with the use of this documentation please contact: grp-ukbbcanceroutcomes@groups.bristol.ac ...
Burrows, Kimberley   +111 more
core   +1 more source

Genome-wide association study comparison analysis based on Hanwoo full-sib family [PDF]

open access: yesAnimal Bioscience
Objective The improvement of carcass traits is essential for the Hanwoo industry because of the Hanwoo grade determination system, and genome-wide association study (GWAS) analysis is an instrumental tool for identifying the genetic factors that impact ...
Ji-Yeong Kim   +5 more
doaj   +1 more source

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importnace of Lp(a) [PDF]

open access: yes, 2012
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the ...
Postmus, Iris   +65 more
core   +1 more source

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

open access: yesGenome Medicine, 2018
Background Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities.
Eilis Hannon   +22 more
doaj   +1 more source

Syringohydromyelia in Dogs: The Genomic Component Underlying a Complex Neurological Disease

open access: yesAnimals, 2022
Syringohydromyelia (SHM) is a neurological disorder characterized by the appearance of fluid-containing cavities within the spinal cord. Although SHM is thought to be under multigenic control, the molecular basis of this disease remains poorly defined. A
Sandra Andrino   +5 more
doaj   +1 more source

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes [PDF]

open access: yes, 2014
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies ...
Rasmussen-Torvik, Laura J.   +999 more
core   +2 more sources

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain [PDF]

open access: yes, 2015
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK.
Harshal A. Deshmukh   +20 more
core   +1 more source

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