Results 11 to 20 of about 28,777,576 (349)
GenPIP: In-Memory Acceleration of Genome Analysis via Tight Integration of Basecalling and Read Mapping [PDF]
Micro, 2022 Nanopore sequencing is a widely-used high-throughput genome sequencing technology that can sequence long fragments of a genome into raw electrical signals at low cost.
Haiyu Mao +8 more
semanticscholar +1 more source
Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling
BMC Genomics, 2021 Background Elucidation of immune populations with single-cell RNA-seq has greatly benefited the field of immunology by deepening the characterization of immune heterogeneity and leading to the discovery of new subtypes.
Tracy M. Yamawaki +10 more
doaj +1 more source
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations.
Cell, 2021 Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to crop evolution, domestication, and improvement. Here, we assembled 31 high-quality genomes of genetically diverse rice accessions.
P. Qin +28 more
semanticscholar +1 more source
Wnt signaling related transcripts and their relationship to energy metabolism in C2C12 myoblasts under temperature stress [PDF]
PeerJ, 2021 Temperature stress is one of the main environmental stressors affecting the welfare, health and productivity of livestock. Temperature changes can modify cell membrane components, disrupting the crosstalk between the cell and its surroundings by ...
Marua Abu Risha +7 more
doaj +2 more sources
Pan-3D genome analysis reveals structural and functional differentiation of soybean genomes
Genome Biology, 2023 Background High-order chromatin structure plays important roles in gene regulation. However, the diversity of the three-dimensional (3D) genome across plant accessions are seldom reported.
Lingbin Ni +11 more
semanticscholar +1 more source
IPGA: A handy integrated prokaryotes genome and pan‐genome analysis web service
iMeta, 2022 Pan‐genomics is one of the most powerful means to study genomic variation and obtain a sketch of genes within a defined clade of species. Though there are a lot of computational tools to achieve this, an integrated framework to evaluate their performance
Dongmei Liu +9 more
semanticscholar +1 more source
Spectrogram Analysis of Genomes [PDF]
EURASIP Journal on Advances in Signal Processing, 2004 We performed frequency-domain analysis in the genomes of various organisms using tricolor spectrograms, identifying several types of distinct visual patterns characterizing specific DNA regions. We relate patterns and their frequency characteristics to the sequence characteristics of the DNA.
David Sussillo +2 more
openaire +3 more sources
BMC Genomics, 2021 Background Archival formalin-fixed, paraffin-embedded (FFPE) tissue samples with clinical and histological data are a singularly valuable resource for developing new molecular biomarkers.
Jin Sung Jang +7 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2022 We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level.
M. Alser +7 more
semanticscholar +1 more source
Pooled Screens Identify GPR108 and TM9SF2 as Host Cell Factors Critical for AAV Transduction
Molecular Therapy: Methods & Clinical Development, 2020 Adeno-associated virus (AAV) has been used extensively as a vector for gene therapy. Despite its widespread use, the mechanisms by which AAV enters the cell and is trafficked to the nucleus are poorly understood.
W. Hans Meisen +8 more
doaj +1 more source