Results 11 to 20 of about 1,597,445 (261)

Spectrogram Analysis of Genomes [PDF]

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
We performed frequency-domain analysis in the genomes of various organisms using tricolor spectrograms, identifying several types of distinct visual patterns characterizing specific DNA regions. We relate patterns and their frequency characteristics to the sequence characteristics of the DNA.
David Sussillo   +2 more
openaire   +3 more sources

RAB18 is a key regulator of GalNAc-conjugated siRNA-induced silencing in Hep3B cells

open access: yesMolecular Therapy: Nucleic Acids, 2022
Small interfering RNA (siRNA) therapeutics have developed rapidly in recent years, despite the challenges associated with delivery of large, highly charged nucleic acids.
Jiamiao Lu   +9 more
doaj   +1 more source

Comparative Genomics and Functional Genomics Analysis in Plants

open access: yesInternational Journal of Molecular Sciences, 2023
Comparative genomics and functional genomics are two basic branches of plant genomics [...]
Jiacheng Wang, Yaojia Chen, Quan Zou
openaire   +2 more sources

Comparative genome analysis and genome-guided physiological analysis of Roseobacter litoralis [PDF]

open access: yesBMC Genomics, 2011
AbstractBackgroundRoseobacter litoralisOCh149, the type species of the genus, andRoseobacter denitrificansOCh114 were the first described organisms of theRoseobacterclade, an ecologically important group of marine bacteria. Both species were isolated from seaweed and are able to perform aerobic anoxygenic photosynthesis.ResultsThe genome ofR ...
Kalhoefer, Daniela   +8 more
openaire   +4 more sources

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v2; ref status: indexed, http://f1000r.es/2x1]

open access: yesF1000Research, 2014
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

Coronavirus Genomics and Bioinformatics Analysis [PDF]

open access: yesViruses, 2010
The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, with G + C contents varying from 32% to 43%.
Woo, PCY, Lau, SKP, Yuen, KY, Huang, Y
openaire   +5 more sources

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v1; ref status: indexed, http://f1000r.es/28e]

open access: yesF1000Research, 2013
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

Genomic Microarray Analysis [PDF]

open access: yes, 2015
Microarrays utilize classical hybridization techniques to measure the levels of expression of genomic sequences. Advances in microarray fabrication using robotic technology and bioinformatics, now means entire genomes can be interrogated with a high degree of sensitivity, specificity and throughput.
Hamlet, S, Petcu, E, Ivanovski, S
openaire   +3 more sources

Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs

open access: yesBMC Genomics, 2019
Background Epigenetic variation may result from selection for complex traits related to metabolic processes or appear in the course of adaptation to mediate responses to exogenous stressors.
Siriluck Ponsuksili   +5 more
doaj   +1 more source

Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer

open access: yesMolecular Systems Biology, 2012
The EGFR‐driven cell‐cycle pathway has been extensively studied due to its pivotal role in breast cancer proliferation and pathogenesis. Although several studies reported regulation of individual pathway components by microRNAs (miRNAs), little is known ...
Stefan Uhlmann   +12 more
doaj   +1 more source

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