Results 21 to 30 of about 25,229,043 (255)

Pig genome sequence - analysis and publication strategy [PDF]

open access: yes, 2010
Background The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome ...
Fredholm, M.   +49 more
core   +1 more source

Sequencing quality assessment tools to enable data-driven informatics for high throughput genomics

open access: yesFrontiers in Genetics, 2013
The processes of quality assessment and control are an active area of research at The Genome Analysis Centre (TGAC). Unlike other sequencing centres that often concentrate on a certain species or technology, TGAC applies expertise in genomics and ...
Richard Mark Leggett   +4 more
doaj   +1 more source

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

open access: yesPeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun   +5 more
doaj   +2 more sources

RAB18 is a key regulator of GalNAc-conjugated siRNA-induced silencing in Hep3B cells

open access: yesMolecular Therapy: Nucleic Acids, 2022
Small interfering RNA (siRNA) therapeutics have developed rapidly in recent years, despite the challenges associated with delivery of large, highly charged nucleic acids.
Jiamiao Lu   +9 more
doaj   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

open access: yes, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
Joets, Johann   +15 more
core   +1 more source

Novel approach for deriving genome wide SNP analysis data from archived blood spots [PDF]

open access: yes, 2012
BACKGROUND: The ability to transport and store DNA at room temperature in low volumes has the advantage of optimising cost, time and storage space.
Walling, Grant A   +16 more
core   +3 more sources

The Capsaspora genome reveals a complex unicellular prehistory of animals [PDF]

open access: yes, 2013
To reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported
Chen, Zehua   +19 more
core   +1 more source

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v2; ref status: indexed, http://f1000r.es/2x1]

open access: yesF1000Research, 2014
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

Whole-genome sequence-based analysis of thyroid function. [PDF]

open access: yes, 2015
Normal thyroid function is essential for health, but its genetic architecture remains poorly understood. Here, for the heritable thyroid traits thyrotropin (TSH) and free thyroxine (FT4), we analyse whole-genome sequence data from the UK10K project (N=2 ...
Paternoster, Lavinia   +856 more
core   +1 more source

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v1; ref status: indexed, http://f1000r.es/28e]

open access: yesF1000Research, 2013
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

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