Results 21 to 30 of about 2,661,224 (296)

Odyssey: a semi-automated pipeline for phasing, imputation, and analysis of genome-wide genetic data [PDF]

, 2019
BACKGROUND: Genome imputation, admixture resolution and genome-wide association analyses are timely and computationally intensive processes with many composite and requisite steps.
Eller, Ryan J., Janga, Sarath C., Walsh, Susan   +2 more
core   +1 more source

Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer

Molecular Systems Biology, 2012
The EGFR‐driven cell‐cycle pathway has been extensively studied due to its pivotal role in breast cancer proliferation and pathogenesis. Although several studies reported regulation of individual pathway components by microRNAs (miRNAs), little is known ...
Stefan Uhlmann, Heiko Mannsperger, Jitao David Zhang, Emöke‐Ágnes Horvat, Christian Schmidt, Moritz Küblbeck, Frauke Henjes, Aoife Ward, Ulrich Tschulena, Katharina Zweig, Ulrike Korf, Stefan Wiemann, Özgür Sahin   +12 more
doaj   +1 more source

Cancer gene prioritization by integrative analysis of mRNA expression and DNA copy number data: a comparative review [PDF]

, 2011
A variety of genome-wide profiling techniques are available to probe complementary aspects of genome structure and function. Integrative analysis of heterogeneous data sources can reveal higher-level interactions that cannot be detected based on ...
Akavia, Andrews, Baasiri, Chin, Dai, De Bie, Futreal, H.-U. Klein, Haverty, Hawkins, Hyman, Johnson, Kao, L. Lahti, M. Dugas, M. Schafer, McLendon, Menezes, Mullighan, Mullighan, Myllykangas, Olshen, Ortiz-Estevez, Phillips, Qin, S. Bicciato, Solvang, Soneson, Stranger, van Wieringen, van Wieringen   +30 more
core   +2 more sources

A method to simultaneously construct up to 12 differently sized Illumina Nextera long mate pair libraries with reduced DNA input, time, and cost

BioTechniques, 2015
Long mate pair (LMP) or “jump” libraries are invaluable for producing contiguous genome assemblies and assessing structural variation. However the consistent production of high quality (low duplication rate, accurately sized) LMP libraries has proven ...
Darren Heavens, Gonzalo Garcia Accinelli, Bernardo Clavijo, Matthew Derek Clark   +3 more
doaj   +1 more source

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

BMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov, Zhiqun Tang, Anna V. Ivshina   +2 more
doaj   +1 more source

The complete chloroplast genome of Sinomenium acutum (Menispermaceae)

Mitochondrial DNA. Part B. Resources, 2020
We generated the complete chloroplast genome sequence of Sinomenium acutum, a species of the Menispermaceae family, and characterized from the de novo assembly of Illumina HiSeq paired-end sequencing data. The total length of the chloroplast genome of S.
Jinhyuk Kim, Junki Lee, Sanghee Um, Sunseong Choi, Hyojin Kim, Hyang Sook Chun, Gyoungju Nah   +6 more
doaj   +1 more source

Microbial genomic taxonomy [PDF]

, 2013
A need for a genomic species definition is emerging from several independent studies worldwide. In this commentary paper, we discuss recent studies on the genomic taxonomy of diverse microbial groups and a unified species definition based on genomics ...
Chimetto, Luciane, Edwards, Robert A, Stackebrandt, Erko, Swings, Jean, Thompson, Cristiane C, Thompson, Fabiano L   +5 more
core   +3 more sources

The complete chloroplast genome of Typhonium giganteum (Araceae)

Mitochondrial DNA. Part B. Resources, 2020
The complete chloroplast genome sequence of Typhonium giganteum, a species of the Araceae family, was characterized from the de novo assembly of HiSeq (Illumina Co.) paired-end sequencing data. The chloroplast genome of T.
Jinhyuk Kim, Junki Lee, Sunseong Choi, Sanghee Um, Hyojin Kim, Hyang Sook Chun, Gyoungju Nah   +6 more
doaj   +1 more source

Coordinated transcriptional and post-transcriptional epigenetic regulation during skeletal muscle development and growth in pigs

Journal of Animal Science and Biotechnology, 2022
Background N6-methyladenosine (m6A) and DNA 5-methylcytosine (5mC) methylation plays crucial roles in diverse biological processes, including skeletal muscle development and growth.
Du Zhang, Shumei Wu, Xinxin Zhang, Shuqiang Ren, Zhonglin Tang, Fei Gao   +5 more
doaj   +1 more source

Antibody Microarrays: Promises and Problems

BioTechniques, 2002
Antibody microarrays have enormous potential for becoming a tool that will allow, at the protein level, the type of global characterization of molecular mixtures that DNA microarrays already make possible at the RNA and DNA level.
Wlad Kusnezow, Jörg D. Hoheisel
doaj   +1 more source