Results 21 to 30 of about 24,140,078 (295)

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v2; ref status: indexed, http://f1000r.es/2x1]

open access: yesF1000Research, 2014
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

open access: yes, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
Joets, Johann   +15 more
core   +1 more source

Coronavirus Genomics and Bioinformatics Analysis [PDF]

open access: yesViruses, 2010
The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, with G + C contents varying from 32% to 43%.
Woo, PCY, Lau, SKP, Yuen, KY, Huang, Y
openaire   +5 more sources

StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics [v1; ref status: indexed, http://f1000r.es/28e]

open access: yesF1000Research, 2013
Modern sequencing platforms generate enormous quantities of data in ever-decreasing amounts of time. Additionally, techniques such as multiplex sequencing allow one run to contain hundreds of different samples.
Ricardo H. Ramirez-Gonzalez   +6 more
doaj   +1 more source

Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs

open access: yesBMC Genomics, 2019
Background Epigenetic variation may result from selection for complex traits related to metabolic processes or appear in the course of adaptation to mediate responses to exogenous stressors.
Siriluck Ponsuksili   +5 more
doaj   +1 more source

Genomic Microarray Analysis [PDF]

open access: yes, 2015
Microarrays utilize classical hybridization techniques to measure the levels of expression of genomic sequences. Advances in microarray fabrication using robotic technology and bioinformatics, now means entire genomes can be interrogated with a high degree of sensitivity, specificity and throughput.
Hamlet, S, Petcu, E, Ivanovski, S
openaire   +3 more sources

Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer

open access: yesMolecular Systems Biology, 2012
The EGFR‐driven cell‐cycle pathway has been extensively studied due to its pivotal role in breast cancer proliferation and pathogenesis. Although several studies reported regulation of individual pathway components by microRNAs (miRNAs), little is known ...
Stefan Uhlmann   +12 more
doaj   +1 more source

The Capsaspora genome reveals a complex unicellular prehistory of animals [PDF]

open access: yes, 2013
To reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported
Chen, Zehua   +19 more
core   +1 more source

Genomic Analysis in the Age of Human Genome Sequencing [PDF]

open access: yesCell, 2019
Affordable genome sequencing technologies promise to revolutionize the field of human genetics by enabling comprehensive studies that interrogate all classes of genome variation, genome-wide, across the entire allele frequency spectrum. Ongoing projects worldwide are sequencing many thousands-and soon millions-of human genomes as part of various gene ...
Tuuli, Lappalainen   +3 more
openaire   +2 more sources

A method to simultaneously construct up to 12 differently sized Illumina Nextera long mate pair libraries with reduced DNA input, time, and cost

open access: yesBioTechniques, 2015
Long mate pair (LMP) or “jump” libraries are invaluable for producing contiguous genome assemblies and assessing structural variation. However the consistent production of high quality (low duplication rate, accurately sized) LMP libraries has proven ...
Darren Heavens   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy