Results 51 to 60 of about 28,777,576 (349)

Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis

Nature Communications, 2020
Viral whole-genome sequencing (WGS) provides critical insight into the transmission and evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
R. Bull, T. Adikari, James M. Ferguson, J. Hammond, Igor Stevanovski, Alicia Beukers, Z. Naing, M. Yeang, Andrey Verich, Hasindu Gamaarachchi, K. W. Kim, F. Luciani, S. Stelzer-Braid, John-Sebastian Eden, W. Rawlinson, S. Van Hal, I. Deveson   +16 more
semanticscholar   +1 more source

A method to simultaneously construct up to 12 differently sized Illumina Nextera long mate pair libraries with reduced DNA input, time, and cost

BioTechniques, 2015
Long mate pair (LMP) or “jump” libraries are invaluable for producing contiguous genome assemblies and assessing structural variation. However the consistent production of high quality (low duplication rate, accurately sized) LMP libraries has proven ...
Darren Heavens, Gonzalo Garcia Accinelli, Bernardo Clavijo, Matthew Derek Clark   +3 more
doaj   +1 more source

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

BMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov, Zhiqun Tang, Anna V. Ivshina   +2 more
doaj   +1 more source

The complete chloroplast genome of Sinomenium acutum (Menispermaceae)

Mitochondrial DNA. Part B. Resources, 2020
We generated the complete chloroplast genome sequence of Sinomenium acutum, a species of the Menispermaceae family, and characterized from the de novo assembly of Illumina HiSeq paired-end sequencing data. The total length of the chloroplast genome of S.
Jinhyuk Kim, Junki Lee, Sanghee Um, Sunseong Choi, Hyojin Kim, Hyang Sook Chun, Gyoungju Nah   +6 more
doaj   +1 more source

Characterising genome architectures using genome decomposition analysis [PDF]

BMC Genomics, 2021
AbstractGenome architecture describes how genes and other features are arranged in genomes. These arrangements reflect the evolutionary pressures on genomes and underlie biological processes such as chromosomal segregation and the regulation of gene expression.
Eerik Aunin, Matthew Berriman, Adam James Reid   +2 more
openaire   +4 more sources

The complete chloroplast genome of Typhonium giganteum (Araceae)

Mitochondrial DNA. Part B. Resources, 2020
The complete chloroplast genome sequence of Typhonium giganteum, a species of the Araceae family, was characterized from the de novo assembly of HiSeq (Illumina Co.) paired-end sequencing data. The chloroplast genome of T.
Jinhyuk Kim, Junki Lee, Sunseong Choi, Sanghee Um, Hyojin Kim, Hyang Sook Chun, Gyoungju Nah   +6 more
doaj   +1 more source

Microbial genomic taxonomy [PDF]

, 2013
A need for a genomic species definition is emerging from several independent studies worldwide. In this commentary paper, we discuss recent studies on the genomic taxonomy of diverse microbial groups and a unified species definition based on genomics ...
Chimetto, Luciane, Edwards, Robert A, Stackebrandt, Erko, Swings, Jean, Thompson, Cristiane C, Thompson, Fabiano L   +5 more
core   +3 more sources

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]

, 2020
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David, Beliveau, Brian, Cavalli, Giacomo, KARPEN, Gary H., Lee, Yuh, Martins, Nuno, Ogiyama, Yuki, Wu, C-Ting   +7 more
core   +3 more sources

From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

, 2005
Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge.
A. Subramanian, P. Tamayo, V. Mootha, Sayan Mukherjee, B. Ebert, Michael A. Gillette, A. Paulovich, S. Pomeroy, T. Golub, E. Lander, J. Mesirov   +10 more
semanticscholar   +1 more source

Coordinated transcriptional and post-transcriptional epigenetic regulation during skeletal muscle development and growth in pigs

Journal of Animal Science and Biotechnology, 2022
Background N6-methyladenosine (m6A) and DNA 5-methylcytosine (5mC) methylation plays crucial roles in diverse biological processes, including skeletal muscle development and growth.
Du Zhang, Shumei Wu, Xinxin Zhang, Shuqiang Ren, Zhonglin Tang, Fei Gao   +5 more
doaj   +1 more source