Results 61 to 70 of about 28,777,576 (349)
Initial sequencing and analysis of the human genome
Nature, 2001 The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human ...
E. Lander +255 more
semanticscholar +1 more source
Antibody Microarrays: Promises and Problems
BioTechniques, 2002 Antibody microarrays have enormous potential for becoming a tool that will allow, at the protein level, the type of global characterization of molecular mixtures that DNA microarrays already make possible at the RNA and DNA level.
Wlad Kusnezow, Jörg D. Hoheisel
doaj +1 more source
Complete chloroplast genome of Gypsophila oldhamiana Miq. (Caryophyllales: Caryophyllaceae)
Mitochondrial DNA. Part B. Resources, 2021 The complete chloroplast genome sequence of Gypsophila oldhamiana Miq., a species of the Caryophyllaceae family, was assembled and analyzed from the de novo assembly of Illumina paired-end sequencing data. The total length of the chloroplast genome of G.
Ji Ran Jeong +5 more
doaj +1 more source
GenColors: Annotation and comparative genomics made easy [PDF]
, 2009 GenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al., _Bioinformatics_ 2005; Romualdi et al., _Methods Mol.
Alessandro Romualdi +4 more
core +2 more sources
BPGA- an ultra-fast pan-genome analysis pipeline
Scientific Reports, 2016 Recent advances in ultra-high-throughput sequencing technology and metagenomics have led to a paradigm shift in microbial genomics from few genome comparisons to large-scale pan-genome studies at different scales of phylogenetic resolution.
Narendrakumar M. Chaudhari +2 more
semanticscholar +1 more source
Whole-exome sequencing uncovered the 3-hydroxy-3-methylglutaryl-CoA lyase deficiency as the cause of lethal in a Vietnamese infant [PDF]
Exploration of Endocrine and Metabolic DiseasesMetabolic disorders are due to a deficiency of enzymes, which can severely impact health or cause serious complications without treatment. This study aimed to identify the molecular causes of an infant death who had been hospitalized with complicated ...
Hong Thu Nguyen-Huu +3 more
doaj +1 more source
The Cancer Genome Atlas Pan-Cancer Analysis Project
Nature Genetics, 2013 Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a dozen different types of cancer ...
J. Weinstein +8 more
semanticscholar +1 more source
5’isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1
Journal of Experimental & Clinical Cancer Research, 2022 Background MicroRNAs (miRNAs) and isomiRs play important roles in tumorigenesis as essential regulators of gene expression. 5’isomiRs exhibit a shifted seed sequence compared to the canonical miRNA, resulting in different target spectra and thereby ...
Xiaoya Li +19 more
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Replicability analysis for genome-wide association studies
, 2014 The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing replicability of associations are scarce. Published GWA studies often combine separately the results
Heller, Ruth, Yekutieli, Daniel
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Unified theory of human genome reveals a constrained spatial chromosomal arrangement in interphase nuclei [PDF]
, 2015 We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across all pairs of ...
Fatakia, Sarosh N. +2 more
core +2 more sources