Results 21 to 30 of about 300,948 (293)
Improving pan-genome annotation using whole genome multiple alignment
BMC Bioinformatics, 2011 Background Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology.
Salzberg Steven L +3 more
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Bovine Genome Database: supporting community annotation and analysis of the
BMC Genomics, 2010 Background A goal of the Bovine Genome Database (BGD; http://BovineGenome.org) has been to support the Bovine Genome Sequencing and Analysis Consortium (BGSAC) in the annotation and analysis of the bovine genome.
Childs Kevin L +6 more
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mSystems, 2020 Prokaryotic genome annotation is heavily dependent on automated gene annotation pipelines that are prone to propagate errors and underestimate genome complexity.
Patrick Willems +2 more
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The automatic annotation of bacterial genomes [PDF]
Briefings in Bioinformatics, 2012 With the development of ultra-high-throughput technologies, the cost of sequencing bacterial genomes has been vastly reduced. As more genomes are sequenced, less time can be spent manually annotating those genomes, resulting in an increased reliance on automatic annotation pipelines. However, automatic pipelines can produce inaccurate genome annotation
Richardson, Emily, Watson, Mick
openaire +3 more sources
BMC Bioinformatics, 2011 Background Second-generation sequencing technologies are precipitating major shifts with regards to what kinds of genomes are being sequenced and how they are annotated.
Holt Carson, Yandell Mark
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Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing
Biology, 2020 Next-Generation Sequencing (NGS) has made it easier to obtain genome-wide sequence data and it has shifted the research focus into genome annotation. The challenging tasks involved in annotation rely on the currently available tools and techniques to ...
Girum Fitihamlak Ejigu, Jaehee Jung
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Correction of the Caulobacter crescentus NA1000 genome annotation. [PDF]
PLoS ONE, 2014 Bacterial genome annotations are accumulating rapidly in the GenBank database and the use of automated annotation technologies to create these annotations has become the norm.
Bert Ely, LaTia Etheredge Scott
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BMC Bioinformatics, 2007 Background Apollo, a genome annotation viewer and editor, has become a widely used genome annotation and visualization tool for distributed genome annotation projects.
Mayer Klaus FX +3 more
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Genome (re‐)annotation and open‐source annotation pipelines [PDF]
Microbial Biotechnology, 2010 These days, more and more scientists are diving into genome sequencing projects, urged by fast and cheap next‐generation sequencing technologies. Only to discover that they are quickly drowning in an unfathomable sea of sequence data and gasping for help from experts to make biological sense of this ensuing disaster.
Siezen, R.J., Hijum, S.A.F.T. van
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BarkBase: Epigenomic Annotation of Canine Genomes [PDF]
Genes, 2019 Dogs are an unparalleled natural model for investigating the genetics of health and disease, particularly for complex diseases like cancer. Comprehensive genomic annotation of regulatory elements active in healthy canine tissues is crucial both for identifying candidate causal variants and for designing functional studies needed to translate genetic ...
Lynne J. Anguish +21 more
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