Results 21 to 30 of about 1,479,681 (326)

RefSeq: expanding the Prokaryotic Genome Annotation Pipeline reach with protein family model curation

open access: yesNucleic Acids Res., 2020
The Reference Sequence (RefSeq) project at the National Center for Biotechnology Information (NCBI) contains nearly 200 000 bacterial and archaeal genomes and 150 million proteins with up-to-date annotation.
Wenjun Li   +20 more
semanticscholar   +1 more source

EuCAP, a Eukaryotic Community Annotation Package, and its application to the rice genome

open access: yesBMC Genomics, 2007
Background Despite the improvements of tools for automated annotation of genome sequences, manual curation at the structural and functional level can provide an increased level of refinement to genome annotation.
Hamilton John P   +4 more
doaj   +1 more source

Manual Annotation Studio (MAS): a collaborative platform for manual functional annotation of viral and microbial genomes

open access: yesBMC Genomics, 2021
Background Functional genome annotation is the process of labelling functional genomic regions with descriptive information. Manual curation can produce higher quality genome annotations than fully automated methods.
Matthew R. Lueder   +6 more
doaj   +1 more source

GENCODE: The reference human genome annotation for The ENCODE Project

open access: yesGenome Research, 2012
The GENCODE Consortium aims to identify all gene features in the human genome using a combination of computational analysis, manual annotation, and experimental validation.
J. Harrow   +40 more
semanticscholar   +1 more source

Improvements to the Gulf pipefish Syngnathus scovelli genome

open access: yesGigaByte, 2023
The Gulf pipefish Syngnathus scovelli has emerged as an important species for studying sexual selection, development, and physiology. Comparative evolutionary genomics research involving fishes from Syngnathidae depends on having a high ...
Balan Ramesh   +9 more
doaj   +1 more source

Whole-Genome Annotation with BRAKER. [PDF]

open access: yesMethods in molecular biology, 2019
BRAKER is a pipeline for highly accurate and fully automated gene prediction in novel eukaryotic genomes. It combines two major tools: GeneMark-ES/ET and AUGUSTUS. GeneMark-ES/ET learns its parameters from a novel genomic sequence in a fully automated fashion; if available, it uses extrinsic evidence for model refinement.
K. Hoff   +3 more
semanticscholar   +3 more sources

Genome annotation for clinical genomic diagnostics: strengths and weaknesses

open access: yesGenome Medicine, 2017
The Human Genome Project and advances in DNA sequencing technologies have revolutionized the identification of genetic disorders through the use of clinical exome sequencing.
Charles A. Steward   +5 more
doaj   +1 more source

RGAAT: A Reference-based Genome Assembly and Annotation Tool for New Genomes and Upgrade of Known Genomes

open access: yesGenomics, Proteomics & Bioinformatics, 2018
The rapid development of high-throughput sequencing technologies has led to a dramatic decrease in the money and time required for de novo genome sequencing or genome resequencing projects, with new genome sequences constantly released every week.
Wanfei Liu   +8 more
doaj   +1 more source

Status of genome function annotation in model organisms and crops

open access: yesPlant Direct, 2023
Since the entry into genome‐enabled biology several decades ago, much progress has been made in determining, describing, and disseminating the functions of genes and their products.
Bo Xue, Seung Y. Rhee
doaj   +1 more source

Improved Reference Genome Annotation of Brassica rapa by Pacific Biosciences RNA Sequencing

open access: yesFrontiers in Plant Science, 2022
The species Brassica rapa includes several important vegetable crops. The draft reference genome of B. rapa ssp. pekinensis was completed in 2011, and it has since been updated twice. The pangenome with structural variations of 18 B.
Zhicheng Zhang   +8 more
semanticscholar   +1 more source

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