Status of genome function annotation in model organisms and crops
Since the entry into genome‐enabled biology several decades ago, much progress has been made in determining, describing, and disseminating the functions of genes and their products.
Bo Xue, Seung Y. Rhee
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Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs [PDF]
The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting the results of RNA-seq experiments where short sequence reads are mapped ...
A Derti +52 more
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The rapid development of high-throughput sequencing technologies has led to a dramatic decrease in the money and time required for de novo genome sequencing or genome resequencing projects, with new genome sequences constantly released every week.
Wanfei Liu +8 more
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Annotation confidence score for genome annotation: a genome comparison approach [PDF]
Abstract Motivation: The massively parallel sequencing technology can be used by small research labs to generate genome sequences of their research interest. However, annotation of genomes still relies on the manual process, which becomes a serious bottleneck to the high-throughput genome projects.
Donald L. Gilbert, Sun Kim, Youngik Yang
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Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop
Improvements in DNA sequencing technologies portend a new era in virology and could possibly lead to a giant leap in our understanding of viral evolution and ecology.
Qiandong Zeng +14 more
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GenColors: Annotation and comparative genomics made easy [PDF]
GenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al., _Bioinformatics_ 2005; Romualdi et al., _Methods Mol.
Alessandro Romualdi +4 more
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Improving pan-genome annotation using whole genome multiple alignment
Background Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology.
Salzberg Steven L +3 more
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REPARATION : ribosome profiling assisted (re-)annotation of bacterial genomes [PDF]
Prokaryotic genome annotation is highly dependent on automated methods, as manual curation cannot keep up with the exponential growth of sequenced genomes.
Giess, Adam +5 more
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Bovine Genome Database: supporting community annotation and analysis of the 
Background A goal of the Bovine Genome Database (BGD; http://BovineGenome.org) has been to support the Bovine Genome Sequencing and Analysis Consortium (BGSAC) in the annotation and analysis of the bovine genome.
Childs Kevin L +6 more
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Correction of the Caulobacter crescentus NA1000 genome annotation. [PDF]
Bacterial genome annotations are accumulating rapidly in the GenBank database and the use of automated annotation technologies to create these annotations has become the norm.
Bert Ely, LaTia Etheredge Scott
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