Results 31 to 40 of about 342,168 (262)

MAKER2: an annotation pipeline and genome-database management tool for second-generation genome projects

open access: yesBMC Bioinformatics, 2011
Background Second-generation sequencing technologies are precipitating major shifts with regards to what kinds of genomes are being sequenced and how they are annotated.
Holt Carson, Yandell Mark
doaj   +1 more source

Tips for improving genome annotation quality

open access: yesGenomics Communications
With the advancement of sequencing technology and genome assembly algorithms, we can easily obtain high-quality genome assembly results, however, the remaining challenge is accurate genome annotation. As the cornerstone for downstream analysis, there are
Lan Lan   +6 more
doaj   +1 more source

Correction of the Caulobacter crescentus NA1000 genome annotation. [PDF]

open access: yesPLoS ONE, 2014
Bacterial genome annotations are accumulating rapidly in the GenBank database and the use of automated annotation technologies to create these annotations has become the norm.
Bert Ely, LaTia Etheredge Scott
doaj   +1 more source

The genome sequence of the common frog, Rana temporaria Linnaeus 1758 [version 1; peer review: 2 approved]

open access: yesWellcome Open Research, 2021
We present a genome assembly from an individual female Rana temporaria (the common frog; Chordata; Amphibia; Anura; Ranidae). The genome sequence is 4.11 gigabases in span.
Jeffrey W. Streicher
doaj   +1 more source

Lost and Found: Re-searching and Re-scoring Proteomics Data Aids Genome Annotation and Improves Proteome Coverage

open access: yesmSystems, 2020
Prokaryotic genome annotation is heavily dependent on automated gene annotation pipelines that are prone to propagate errors and underestimate genome complexity.
Patrick Willems   +2 more
doaj   +1 more source

Complete genome sequencing of Bacillus cabrialesii TE3T: A plant growth-promoting and biological control agent isolated from wheat (Triticum turgidum subsp. durum) in the Yaqui Valley

open access: yesCurrent Research in Microbial Sciences, 2023
Bacillus cabrialesii TE3T is a strictly aerobic and Gram-stain-positive plant growth-promoting bacterium, motile and catalase-positive. In addition, strain TE3T was also recently described as a biological control agent.
Valeria Valenzuela Ruiz   +5 more
doaj   +1 more source

Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing

open access: yesBiology, 2020
Next-Generation Sequencing (NGS) has made it easier to obtain genome-wide sequence data and it has shifted the research focus into genome annotation. The challenging tasks involved in annotation rely on the currently available tools and techniques to ...
Girum Fitihamlak Ejigu, Jaehee Jung
doaj   +1 more source

Apollo2Go: a web service adapter for the Apollo genome viewer to enable distributed genome annotation

open access: yesBMC Bioinformatics, 2007
Background Apollo, a genome annotation viewer and editor, has become a widely used genome annotation and visualization tool for distributed genome annotation projects.
Mayer Klaus FX   +3 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

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