Results 51 to 60 of about 1,440,487 (305)
Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum [PDF]
Background Stagonospora nodorum, a fungal ascomycete in the class dothideomycetes, is a damaging pathogen of wheat. It is a model for necrotrophic fungi that cause necrotic symptoms via the interaction of multiple effector proteins with cultivar ...
Hane, J. +24 more
core +1 more source
Background Apollo, a genome annotation viewer and editor, has become a widely used genome annotation and visualization tool for distributed genome annotation projects.
Mayer Klaus FX +3 more
doaj +1 more source
Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing
Next-Generation Sequencing (NGS) has made it easier to obtain genome-wide sequence data and it has shifted the research focus into genome annotation. The challenging tasks involved in annotation rely on the currently available tools and techniques to ...
Girum Fitihamlak Ejigu, Jaehee Jung
doaj +1 more source
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
CoryneCenter: an online resource for the integrated analysis of corynebacterial genome and transcriptome data [PDF]
Neuweger H, Baumbach J, Albaum S, et al. CoryneCenter: an online resource for the integrated analysis of corynebacterial genome and transcriptome data. BMC Systems Biology.
Hüser, Andrea T. +23 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Segmentation and genome annotation algorithms
Segmentation and genome annotation (SAGA) algorithms are widely used to understand genome activity and gene regulation. These algorithms take as input epigenomic datasets, such as chromatin immunoprecipitation-sequencing (ChIP-seq) measurements of histone modifications or transcription factor binding.
Maxwell W. Libbrecht +2 more
openaire +2 more sources
Genome (re‐)annotation and open‐source annotation pipelines [PDF]
These days, more and more scientists are diving into genome sequencing projects, urged by fast and cheap next‐generation sequencing technologies. Only to discover that they are quickly drowning in an unfathomable sea of sequence data and gasping for help from experts to make biological sense of this ensuing disaster.
Siezen, R.J., Hijum, S.A.F.T. van
openaire +3 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Background The location and modular structure of eukaryotic protein-coding genes in genomic sequences can be automatically predicted by gene annotation algorithms.
Jeanne Wilbrandt +3 more
doaj +1 more source

