Results 51 to 60 of about 1,440,487 (305)

Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum [PDF]

open access: yes, 2009
Background Stagonospora nodorum, a fungal ascomycete in the class dothideomycetes, is a damaging pathogen of wheat. It is a model for necrotrophic fungi that cause necrotic symptoms via the interaction of multiple effector proteins with cultivar ...
Hane, J.   +24 more
core   +1 more source

Apollo2Go: a web service adapter for the Apollo genome viewer to enable distributed genome annotation

open access: yesBMC Bioinformatics, 2007
Background Apollo, a genome annotation viewer and editor, has become a widely used genome annotation and visualization tool for distributed genome annotation projects.
Mayer Klaus FX   +3 more
doaj   +1 more source

Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing

open access: yesBiology, 2020
Next-Generation Sequencing (NGS) has made it easier to obtain genome-wide sequence data and it has shifted the research focus into genome annotation. The challenging tasks involved in annotation rely on the currently available tools and techniques to ...
Girum Fitihamlak Ejigu, Jaehee Jung
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

CoryneCenter: an online resource for the integrated analysis of corynebacterial genome and transcriptome data [PDF]

open access: yes, 2007
Neuweger H, Baumbach J, Albaum S, et al. CoryneCenter: an online resource for the integrated analysis of corynebacterial genome and transcriptome data. BMC Systems Biology.
Hüser, Andrea T.   +23 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Segmentation and genome annotation algorithms

open access: yesCoRR, 2021
Segmentation and genome annotation (SAGA) algorithms are widely used to understand genome activity and gene regulation. These algorithms take as input epigenomic datasets, such as chromatin immunoprecipitation-sequencing (ChIP-seq) measurements of histone modifications or transcription factor binding.
Maxwell W. Libbrecht   +2 more
openaire   +2 more sources

Genome (re‐)annotation and open‐source annotation pipelines [PDF]

open access: yesMicrobial Biotechnology, 2010
These days, more and more scientists are diving into genome sequencing projects, urged by fast and cheap next‐generation sequencing technologies. Only to discover that they are quickly drowning in an unfathomable sea of sequence data and gasping for help from experts to make biological sense of this ensuing disaster.
Siezen, R.J., Hijum, S.A.F.T. van
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Repertoire-wide gene structure analyses: a case study comparing automatically predicted and manually annotated gene models

open access: yesBMC Genomics, 2019
Background The location and modular structure of eukaryotic protein-coding genes in genomic sequences can be automatically predicted by gene annotation algorithms.
Jeanne Wilbrandt   +3 more
doaj   +1 more source

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