Results 31 to 40 of about 1,479,681 (326)

Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop

Viruses, 2010
Improvements in DNA sequencing technologies portend a new era in virology and could possibly lead to a giant leap in our understanding of viral evolution and ecology.
Qiandong Zeng, William Klimke, Peter Sterk, Susmita Shrivastava, Ramana Madupu, Richard H. Scheuermann, Seth Schobel, Donald Seto, Yiming Bao, Carla Kuiken, Elliot J. Lefkowitz, Philippe Le Mercier, Raphael Leplae, Tatiana Tatusova, James Rodney Brister   +14 more
doaj   +1 more source

Improving pan-genome annotation using whole genome multiple alignment

BMC Bioinformatics, 2011
Background Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology.
Salzberg Steven L, Dunning Hotopp Julie C, Angiuoli Samuel V, Tettelin Hervé   +3 more
doaj   +1 more source

Bovine Genome Database: supporting community annotation and analysis of the Bos taurus genome

BMC Genomics, 2010
Background A goal of the Bovine Genome Database (BGD; http://BovineGenome.org) has been to support the Bovine Genome Sequencing and Analysis Consortium (BGSAC) in the annotation and analysis of the bovine genome.
Childs Kevin L, Dickens C Michael, Sundaram Jaideep P, Childers Christopher P, Reese Justin T, Vile Donald C, Elsik Christine G   +6 more
doaj   +1 more source

Mouse genomic and cellular annotations [PDF]

Mammalian Genome, 2022
AbstractMice have emerged as one of the most popular and valuable model organisms in the research of human biology. This is due to their genetic and physiological similarity to humans, short generation times, availability of genetically homologous inbred strains, and relatively easy laboratory maintenance.
Long, Helen, Reeves, Richard, Simon, Michelle M.   +2 more
openaire   +2 more sources

Correction of the Caulobacter crescentus NA1000 genome annotation. [PDF]

PLoS ONE, 2014
Bacterial genome annotations are accumulating rapidly in the GenBank database and the use of automated annotation technologies to create these annotations has become the norm.
Bert Ely, LaTia Etheredge Scott
doaj   +1 more source

Genome annotation of disease-causing microorganisms

Briefings Bioinform., 2021
Humans have coexisted with pathogenic microorganisms throughout its history of evolution. We have never halted the exploration of pathogenic microorganisms.
Yibo Dong, Chang Li, Kami Kim, L. Cui, Xiaoming Liu   +4 more
semanticscholar   +1 more source

Annotating the Insect Regulatory Genome [PDF]

Insects, 2021
An ever-growing number of insect genomes is being sequenced across the evolutionary spectrum. Comprehensive annotation of not only genes but also regulatory regions is critical for reaping the full benefits of this sequencing. Driven by developments in sequencing technologies and in both empirical and computational discovery strategies, the past few ...
Hasiba Asma, Marc S. Halfon
openaire   +3 more sources

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Nucleic Acids Res., 2018
Proteins and their functional interactions form the backbone of the cellular machinery. Their connectivity network needs to be considered for the full understanding of biological phenomena, but the available information on protein–protein associations is
Damian Szklarczyk, Annika L. Gable, D. Lyon, Alexander Junge, S. Wyder, J. Huerta-Cepas, M. Simonovic, N. Doncheva, J. Morris, P. Bork, L. Jensen, C. V. Mering   +11 more
semanticscholar   +1 more source

Annotation confidence score for genome annotation: a genome comparison approach [PDF]

Bioinformatics, 2009
Abstract Motivation: The massively parallel sequencing technology can be used by small research labs to generate genome sequences of their research interest. However, annotation of genomes still relies on the manual process, which becomes a serious bottleneck to the high-throughput genome projects.
Youngik, Yang, Donald, Gilbert, Sun, Kim
openaire   +2 more sources

Tips for improving genome annotation quality

Genomics Communications
With the advancement of sequencing technology and genome assembly algorithms, we can easily obtain high-quality genome assembly results, however, the remaining challenge is accurate genome annotation. As the cornerstone for downstream analysis, there are
Lan Lan, Haifei Hu, Yong Jia, Xiaoni Zhang, Minlong Jia, Chengdao Li, Zhiqiang Wu   +6 more
doaj   +1 more source