Results 1 to 10 of about 571,422 (359)

Microbial Genome Editing

, 2023
Creative Biogene has the capacity to specifically modify microbial genomes in an efficient and precise way. With talented staffs, advanced technologies and state-of-the-art facilities, Creative Biogene provides microbial genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination system.
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Advances in editing microalgae genomes [PDF]

Perspectives in Phycology, 2017
There have been significant advances in microalgal genomics over the last decade. Nevertheless, there are still insufficient tools for the manipulation of microalgae genomes and the development of microalgae as industrial biofactories. Several research groups have recently contributed to progress by demonstrating that particular nucleases can be used ...
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Regional Physical Mapping: Genome Analysis, vol. 5. Edited by K. E. Davies, and S. M. Tilghman. Cold Spring Harbor Laboratory Press. 1993. 140 pages. Cloth. $49.00. ISBN 0 87969 413 0. [PDF]

, 1994
Wendy A. Bickmore
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CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development

Viruses, 2018
The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches.
Arinze Okoli, Malachy I. Okeke, Morten Tryland, Ugo Moens   +3 more
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scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics

Genome Biology
CRISPR screens with single-cell transcriptomic readouts are a valuable tool to understand the effect of genetic perturbations including single nucleotide variants (SNVs) associated with diseases.
Sarah E. Cooper, Matthew A. Coelho, Magdalena E. Strauss, Aleksander M. Gontarczyk, Qianxin Wu, Mathew J. Garnett, John C. Marioni, Andrew R. Bassett   +7 more
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Human Genome Evolution. Edited by M. Jackson, T. Strachan and G. Dover. BIOS Scientific Publishers, 1996. 306 + x pages. Price £60.00 ($120). ISBN 1 859960 95 2. [PDF]

, 1997
Adrian Bird
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Genetic Alternatives for Experimental Adaptation to Colistin in Three Pseudomonas aeruginosa Lineages

Antibiotics
Pseudomonas aeruginosa is characterized by a high adaptive potential, developing resistance in response to antimicrobial pressure. We employed a spatiotemporal evolution model to disclose the pathways of adaptation to colistin, a last-resort polymyxin ...
Igor Chebotar, Tatiana Savinova, Julia Bocharova, Dmitriy Korostin, Peter Evseev, Nikolay Mayanskiy   +5 more
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Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. [PDF]

, 2019
Pooled CRISPR-Cas9 screens are a powerful method for functionally characterizing regulatory elements in the non-coding genome, but off-target effects in these experiments have not been systematically evaluated.
Aradhana, Bassik, Michael C, Bintu, Lacramioara, Ego, Braeden K, Greenleaf, William J, Greenside, Peyton G, Hess, Gaelen T, Kaplow, Irene M, Kundaje, Anshul, Li, Amy, Marinov, Georgi K, Morgens, David W, Phanstiel, Douglas H, Snyder, Michael P, Spees, Kaitlyn, Trevino, Alexandro E, Truong, Alisa, Tycko, Josh, Ursu, Oana, Wainberg, Michael, Yao, David   +20 more
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Letter from the editor: adenosine‐to‐inosine RNA editing in Alu repeats in the human genome [PDF]

, 2005
Keren Levanon, Eli Eisenberg, Gideon Rechavi, Erez Y. Levanon   +3 more
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