Results 1 to 10 of about 418,537 (219)

Tail Wags Dog’s SINE: Retropositional Mechanisms of Can SINE Depend on Its A-Tail Structure

Biology, 2022
SINEs, non-autonomous short retrotransposons, are widespread in mammalian genomes. Their transcripts are generated by RNA polymerase III (pol III). Transcripts of certain SINEs can be polyadenylated, which requires polyadenylation and pol III termination
Sergei A. Kosushkin, Ilia G. Ustyantsev, Olga R. Borodulina, Nikita S. Vassetzky, Dmitri A. Kramerov   +4 more
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RNA Structures and Their Role in Selective Genome Packaging

Viruses, 2021
To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs.
Liqing Ye, Uddhav B. Ambi, Marco Olguin-Nava, Anne-Sophie Gribling-Burrer, Shazeb Ahmad, Patrick Bohn, Melanie M. Weber, Redmond P. Smyth   +7 more
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Sugarcane Water Stress Tolerance Mechanisms and Its Implications on Developing Biotechnology Solutions

Frontiers in Plant Science, 2017
Sugarcane is a unique crop with the ability to accumulate high levels of sugar and is a commercially viable source of biomass for bioelectricity and second-generation bioethanol.
Thais H. S. Ferreira, Max S. Tsunada, Denis Bassi, Pedro Araújo, Lucia Mattiello, Giovanna V. Guidelli, Germanna L. Righetto, Vanessa R. Gonçalves, Prakash Lakshmanan, Marcelo Menossi   +9 more
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ScRpb4, Encoding an RNA Polymerase Subunit from Sugarcane, Is Ubiquitously Expressed and Resilient to Changes in Response to Stress Conditions

Agriculture, 2022
RNA polymerase II is an essential multiprotein complex that transcribes thousands of genes, being a fundamental component of the transcription initiation complex. In eukaryotes, RNA polymerase II is formed by a 10-multisubunit conserved core complex, and
Taehoon Kim, Fábio Ometto Dias, Agustina Gentile, Marcelo Menossi, Kevin Begcy   +4 more
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Systematic Search for Evidence of Interdomain Horizontal Gene Transfer from Prokaryotes to Oomycete Lineages

mSphere, 2016
While most commonly associated with prokaryotes, horizontal gene transfer (HGT) can also have a significant influence on the evolution of microscopic eukaryotes.
Charley G. P. McCarthy, David A. Fitzpatrick   +1 more
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Phylogenomic Reconstruction of the Oomycete Phylogeny Derived from 37 Genomes

mSphere, 2017
The oomycetes are a class of microscopic, filamentous eukaryotes within the Stramenopiles-Alveolata-Rhizaria (SAR) supergroup which includes ecologically significant animal and plant pathogens, most infamously the causative agent of potato blight ...
Charley G. P. McCarthy, David A. Fitzpatrick   +1 more
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Genomic, Network, and Phylogenetic Analysis of the Oomycete Effector Arsenal

mSphere, 2017
The oomycetes are a class of microscopic, filamentous eukaryotes within the stramenopiles-alveolate-Rhizaria (SAR) supergroup and include ecologically significant animal and plant pathogens.
Jamie McGowan, David A. Fitzpatrick
doaj   +1 more source

Habitats Within the Plant Root Differ in Bacterial Network Topology and Taxonomic Assortativity

Molecular Plant-Microbe Interactions, 2023
The root microbiome is composed of distinct epiphytic (rhizosphere) and endophytic (endosphere) habitats. Differences in abiotic and biotic factors drive differences in microbial community diversity and composition between these habitats, though how they
Connor R. Fitzpatrick, Julia Copeland, Pauline W. Wang, David S. Guttman, Peter M. Kotanen, Marc T. J. Johnson   +5 more
doaj   +1 more source

A comparative study of tumour-on-chip models with patient-derived xenografts for predicting chemotherapy efficacy in colorectal cancer patients

Frontiers in Bioengineering and Biotechnology, 2022
Inter-patient and intra-tumour heterogeneity (ITH) have prompted the need for a more personalised approach to cancer therapy. Although patient-derived xenograft (PDX) models can generate drug response specific to patients, they are not sustainable in ...
Louis Jun Ye Ong, Louis Jun Ye Ong, Louis Jun Ye Ong, Louis Jun Ye Ong, Shumei Chia, Stephen Qi Rong Wong, Stephen Qi Rong Wong, Stephen Qi Rong Wong, Xiaoqian Zhang, Huiwen Chua, Jia Min Loo, Wei Yong Chua, Clarinda Chua, Emile Tan, Hannes Hentze, Iain Beehuat Tan, Iain Beehuat Tan, Iain Beehuat Tan, Ramanuj DasGupta, Yi-Chin Toh, Yi-Chin Toh, Yi-Chin Toh, Yi-Chin Toh   +22 more
doaj   +1 more source

SequelTools: a suite of tools for working with PacBio Sequel raw sequence data

BMC Bioinformatics, 2020
Background PacBio sequencing is an incredibly valuable third-generation DNA sequencing method due to very long read lengths, ability to detect methylated bases, and its real-time sequencing methodology.
David E. Hufnagel, Matthew B. Hufford, Arun S. Seetharam   +2 more
doaj   +1 more source