Results 231 to 240 of about 3,706,718 (308)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Silene, a versatile model system: from sex and genome evolution to ecology and speciation. [PDF]

New Phytol
Karrenberg S, Bačovský V, Berardi AE, De Cauwer I, Giraud T, Hartmann FE, Hobza R, Hudzieczek V, Marais GAB, Miladin JR, Oxelman B, Papadopulos AST, Sloan DB, Steven JC, Štorchová H, Touzet P, Van Rossum F.   +16 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Random mutagenesis platform for accelerated genome evolution (RAMPAGE) of <i>Pichia pastoris</i>. [PDF]

Eng Microbiol
Pan Y, Gu X, Lv B, Dong C, Lian J.
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Dynamics of genome evolution in the era of pangenome analysis. [PDF]

Cell Genom
Loegler V, Friedrich A, Schacherer J.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Genome Evolution and the Enigmatic Axial Skeleton of the Hero Shew (Soricidae: Scutisorex Somereni). [PDF]

Genome Biol Evol
Chipps AS, Hutter CR, Demos TC, Esselstyn JA.   +3 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Adaptive genome evolution and metabolic rewiring in the highland poppy <i>Meconopsis integrifolia</i>. [PDF]

Hortic Res
YangJin L, Yuan Y, Zeng S, Hu G, Du M, Xiong H, Jia X, Duan R.   +7 more
europepmc   +1 more source