Results 231 to 240 of about 1,743,586 (380)

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

, 2008
Christophe Corre, Lijiang Song, Sean O’Rourke, Keith Chater, Gregory L. Challis   +4 more
openalex   +1 more source

Microbial genome mining answers longstanding biosynthetic questions [PDF]

, 2012
Jason M. Crawford, Jon Clardy
openalex   +1 more source

Identification of dilated cardiomyopathy‐linked key genes by bioinformatics methods and evaluating the impact of tannic acid and monosodium glutamate in rats

Biotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 377-387, April 2025.
Abstract Dilated cardiomyopathy (DCM) is the most common type of myocardial dysfunction, affecting mostly young adults, but its therapeutic diagnosis and biomarkers for prognosis are lacking. This study aimed to investigate the possible effect of the common food additive monosodium glutamate (MSG) and tannic acid (TA), a phenolic compound, on the key ...
Habibe Karadas, Hilal Tosun, Hamid Ceylan   +2 more
wiley   +1 more source

Transformation-Guided Genome Mining Provides Access to Brominated Lanthipeptides. [PDF]

Org Lett
Saha N, Vidya FNU, Luo Y, van der Donk WA, Agarwal V.   +4 more
europepmc   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

BMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang, Yefei Dai, Yujun Hou, Joshua Stein, Shichen Steven Lin, Chaochen Zhou, Yannan Hou, Rongrong Zhu, Ki‐Bum Lee, Letao Yang   +9 more
wiley   +1 more source

Uncovering a novel biosynthetic gene cluster for sordarin through genome mining in the fungus Talaromyces adpressus. [PDF]

Bioresour Bioprocess
Xu Q, Ren X, Hu L, Xu Q, Zhang X, Deng M, Ye Y, Zhang Y, Lu Y, Qiao Y.   +9 more
europepmc   +1 more source

Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules [PDF]

, 2013
Roland D. Kersten, Nadine Ziemert, David J. Gonzalez, Brendan M. Duggan, Victor Nizet, Pieter C. Dorrestein, Bradley S. Moore   +6 more
openalex   +1 more source

The Biarylitides: Understanding the Structure and Biosynthesis of a Fascinating Class of Cytochrome P450 Modified RiPP Natural Products

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
The biarylitides are fascinating RiPP natural products with small core peptides and diverse peptide crosslinks performed by cytochrome P450 enzymes. Here, we address the discovery and diversity of the biarylitides, methods to analyse these constrained cyclic peptides, the structures of the biarylitide P450 enzymes and address alternate catalytic ...
Leo Padva, Jemma Gullick, Laura J. Coe, Mathias H. Hansen, James J. De Voss, Max Crüsemann, Max J. Cryle   +6 more
wiley   +1 more source

Identification of a Novel Two-Peptide Lantibiotic, Lichenicidin, following Rational Genome Mining for LanM Proteins

, 2009
Máire Begley, Paul D. Cotter, Colin Hill, R. Paul Ross   +3 more
openalex   +1 more source

Expanding the Enzymatic Toolbox for Carboligation: Increasing the Diversity of the ‘Split’ Transketolase Sequence Space

ChemBioChem, Volume 26, Issue 6, March 15, 2025.
Several putative split transketolases were retrieved via (meta)genome mining, increasing our understanding of this type of prokaryotic TK, whose domains are located on two separate subunits. Ten split TKs were purified and tested for erythrulose production, with the best‐performing enzyme kinetically characterized.
Alessia Tonoli, Silvia Anselmi, John M. Ward, Helen C. Hailes, Jack W. E. Jeffries   +4 more
wiley   +1 more source