Results 71 to 80 of about 24,640 (259)

Targeted Assembly of Short Sequence Reads [PDF]

, 2011
As next-generation sequence (NGS) production continues to increase, analysis is becoming a significant bottleneck. However, in situations where information is required only for specific sequence variants, it is not necessary to assemble or align whole ...
Rene L. Warren, René L Warren, Robert A Holt, Warren René L., Rene Warren, Holt Robert A., Robert Holt, Robert A. Holt   +7 more
core   +2 more sources

Chloroplast genome assembly approaches from NGS data

Journal of BioScience and Biotechnology, 2016
The advent of Next Generation Sequencing platforms led to increase of research in whole genome assembly algorithms and software. Illumina Genome Analyzer produces a large amount of sequencing data, with a shorted read length, higher coverage and ...
Zdravka Ivanova, Evelina Daskalova, Georgi Minkov, Vesselin Baev   +3 more
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The results of genome sequencing and assembly.

, 2012
The results of genome sequencing and assembly.
Weili Liang (134620), Jingfa Xiao (134638), Jun Yu (5904), Xiaoying Cui (134632), Chunxia Chen (134627), Biao Kan (107255), Yongbing Zhao (134624)   +6 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Comparing memory-efficient genome assemblers on stand-alone and cloud infrastructures. [PDF]

PLoS ONE, 2013
A fundamental problem in bioinformatics is genome assembly. Next-generation sequencing (NGS) technologies produce large volumes of fragmented genome reads, which require large amounts of memory to assemble the complete genome efficiently.
Dimitrios Kleftogiannis, Panos Kalnis, Vladimir B Bajic   +2 more
doaj   +1 more source

Summary statistics of genome sequencing and assembly.

, 2014
Summary statistics of genome sequencing and assembly.
Peter W. H. Holland (650158), Jean-Michel Carter (650157), Laura Ferguson (95312), William R. Taylor (162523), Casper J. Breuker (163094), Ferdinand Marlétaz (28249), Melanie Gibbs (5209)   +6 more
core   +1 more source

Genome sequence of the Chlamydophila abortus variant strain LLG [PDF]

, 2011
Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3.
Clark, Ewan M., Smith, David George Emslie, Longbottom, D., David G. E. Smith, Spalding, L., Livingstone, M., Vretou, E., Clark, E.M., David Longbottom, Longbottom, David, Lainson, Alex F., Lainson, F.A., Victoria I. Siarkou, Wheelhouse, Nick M., Morag Livingstone, Spalding, Lucy, Wheelhouse, Nick, Lainson, F Alex, Michelle Sait, Wheelhouse, N., Lucy Spalding, Siarkou, Victoria I, Sait, M., Ewan M. Clark, F. Alex Lainson, Siarkou, V.I., Evangelia Vretou, Siarkou, Victoria I., Smith, David, Sait, Michelle, Clark, Ewan M, Nick Wheelhouse, Livingstone, Morag, Smith, David G E, Smith, D.G.E., Vretou, Evangelia   +35 more
core   +1 more source

Assessing the feasibility of GS FLX Pyrosequencing for sequencing the Atlantic salmon genome

BMC Genomics, 2008
Background With a whole genome duplication event and wealth of biological data, salmonids are excellent model organisms for studying evolutionary processes, fates of duplicated genes and genetic and physiological processes associated with complex ...
Lubieniecki Krzysztof P, Jarvie Thomas P, Knight James R, Boroevich Keith A, Bouffard Pascal, Chow William, Levenkova Natasha, Quinn Nicole L, Desany Brian A, Koop Ben F, Harkins Timothy T, Davidson William S   +11 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source