Results 301 to 310 of about 733,963 (352)

Zinc finger proteins: guardians of genome stability. [PDF]

open access: yesFront Cell Dev Biol
Kamaliyan Z, Clarke TL.
europepmc   +1 more source

hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability. [PDF]

open access: yesCell Death Differ
Chen F   +11 more
europepmc   +1 more source

Author Correction: R-loop-dependent promoter-proximal termination ensures genome stability. [PDF]

open access: yesNature
Xu C   +29 more
europepmc   +1 more source
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Epigenetics and genome stability

Mammalian Genome, 2020
Maintaining genome stability is essential to an organism's health and survival. Breakdown of the mechanisms protecting the genome and the resulting genome instability are an important aspect of the aging process and have been linked to diseases such as cancer. Thus, a large network of interconnected pathways is responsible for ensuring genome integrity
Justina X. Feng, Nicole C. Riddle
openaire   +2 more sources

Genome (in)stability at tandem repeats

Seminars in Cell & Developmental Biology, 2021
Repeat sequences account for over half of the human genome and represent a significant source of variation that underlies physiological and pathological states. Yet, their study has been hindered due to limitations in short-reads sequencing technology and difficulties in assembly.
Elisa Balzano   +2 more
openaire   +2 more sources

Genomic stability in reprogramming

Current Opinion in Genetics & Development, 2012
The genetic stability of induced pluripotent stem (iPS) cells has a significant impact on their potential use in regenerative medicine and basic research. Analysis of the genomic integrity of iPS cells suggests a tendency to develop aberrations ranging from whole chromosome trisomies to single nucleotide mutations. Furthermore, fluctuations in telomere
Daniel, Ronen, Nissim, Benvenisty
openaire   +2 more sources

Carotenoids and genomic stability

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2001
Epidemiological evidence abounds for a link between intake of carotenoids from fruit and vegetable foods and relatively low incidence of various cancers. However, intervention trials have shown, in some cases, a significant increase in occurrence of lung cancer in those volunteers taking supplements of beta-carotene.
openaire   +2 more sources

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