Results 171 to 180 of about 2,173,654 (348)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Comparative genomic analysis of Flavobacteriaceae: insights into carbohydrate metabolism, gliding motility and secondary metabolite biosynthesis. [PDF]

, 2020
Asimenia Gavriilidou, Johanna Gutleben, Dennis Versluis, Francesca Forgiarini, Mark WJ van Passel, Colin J. Ingham, Hauke Smidt, Detmer Sipkema   +7 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Genomic analysis of jumbo coliphage fEgEco12. [PDF]

Arch Virol
Badawy S, Skurnik M.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Application of qualifying variants for genomic analysis. [PDF]

Bioinformatics
Lawless D, Saadat A, Oumelloul MA, Boutry S, Stadler V, Österle S, Armida J, Haerry D, Froese DS, Schlapbach LJ, Fellay J.   +10 more
europepmc   +1 more source

Supplementary data for "Genomics of primary and metastatic cutaneous melanoma: a systematic review and meta-analysis"

Hoang Duc, Thi Thanh Nga Bui, Van Tuan Dao, Van Quang Le, Célèste Lebbé, Guilhem Bousquet   +5 more
openalex   +1 more source

Genomic analysis of Salmonella enterica serotype Paratyphi A during an outbreak in Cambodia, 2013–2015

, 2016
Laura Maria Francisca Kuijpers, Simon Le Hello, Nizar Fawal, Laëtitia Fabre, Mathieu Tourdjman, Muriel Dufour, Dara Sar, Chun Kham, Thong Phe, Erika Vlieghe, Christiane Bouchier, Jan Jacobs, François‐Xavier Weill   +12 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Low-level contamination confounds population genomic analysis. [PDF]

G3 (Bethesda)
Ward AK, Scopel EFC, Shuman B, Momany M, Bensasson D.   +4 more
europepmc   +1 more source