Results 181 to 190 of about 2,173,654 (348)

Integrative genomic and pharmacogenomic analysis reveals novel variants and statin response patterns in Indian familial hypercholesterolemia patients

Kumaran Kasinathan, Kumar JS, A. S. Agrawal, Fiona D'Souza, KN Aruljothi   +4 more
openalex   +1 more source

Evolutionary and genomic analysis of four SARS-CoV-2 isolates circulating in March 2020 in Sri Lanka; Additional evidence on multiple introduction and further transmission [PDF]

, 2020
Dilan Amila Satharasinghe, Parakatawella Mudiyanselage Shalini Daupadi Kumari Parakatawella, Jayasekara Mudiyanselage Krishanthi Jayarukshi Kumari Premarathne, L. J. P. A. P. Jayasooriya, Gamika A. Prathapasinghe, Swee Keong Yeap   +5 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Genomic Analysis of Botanical Collections: opportunities and challenges. [PDF]

Plant Cell
Deglialberti M, Paleni C, Fainelli F, Lambertini C, Manrique S.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Correction: AOH induces oxidative stress and DNA damage in ovarian cancer cells via modulation of GPER1 and HIF1α/PI3K/CLDNs signaling pathway

Scientific Reports
Marta Justyna Kozieł-Leszczyńska, Dominika Ewa Habrowska-Górczyńska, Kacper Piotr Leszczyński, Kinga Anna Urbanek, Agnieszka Wanda Piastowska-Ciesielska, Karolina Kowalska   +5 more
doaj   +1 more source

Integrated Genomic Analysis Unveils MicroRNA Roles in Glioma Development. [PDF]

Biology (Basel)
Majed SO, Abdullah GH, Sulaiman KM, Maaruf SM, Yashooa RK, Abdulla SS, Villa C, Mustafa SA.   +7 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Comprehensive genomic analysis reveals the class II diterpene cyclases in Dodonaea viscosa. [PDF]

Phytochemistry
Helwig K, Peters RJ.
europepmc   +1 more source

Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases (要旨) [PDF]

, 2021
明生 塩見
openalex