Results 201 to 210 of about 2,173,654 (348)

Supplemental legend and tables from Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling

, 2023
Klaus Griewank, Christian Koelsche, Johannes A.P. van de Nes, Daniel Schrimpf, Marco Gessi, Inga Möller, Antje Sucker, Richard A. Scolyer, Michael E. Buckland, Rajmohan Murali, Torsten Pietsch, Andreas von Deimling, Dirk Schadendorf   +12 more
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Genomic Analysis and Population Divergence Driven by Geographic Isolation in <i>Neotetracus sinensis</i>. [PDF]

Ecol Evol
Zhou J, Chen N, Dou W, Luo Z, Jiang L, Jing M, Yang F.   +6 more
europepmc   +1 more source

Additional file 29 of Comparative functional genomics analysis of cytochrome P450 gene superfamily in wheat and maize

, 2020
Yixuan Li, Kaifa Wei
openalex   +1 more source

Supplementary Tables from Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer

, 2023
Théo Z. Hirsch, Jill Pilet, Guillaume Morcrette, Amélie Roehrig, Benedict J.E. Monteiro, Laura Molina, Quentin Bayard, Eric Trépo, Léa Meunier, Stefano Caruso, Victor Renault, Jean‐François Deleuze, Brice Fresneau, Christophe Chardot, Emmanuel Gonzalès, Emmanuel Jacquemin, Florent Guérin, Monique Fabrè, Isabelle Aerts, Sophie Taque, Véronique Laithier, Sophie Branchereau, Catherine Guettier, Laurence Brugières, Sandra Rebouissou, Éric Letouzé, Jessica Zucman‐Rossi   +26 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Genomic analysis of the Ixworth chicken: insights into a local dual-purpose breed. [PDF]

BMC Genomics
Bertram H, Jawad M, Michanski S, Tiemann I, Schmitt AO, Gültas M.   +5 more
europepmc   +1 more source

Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Changes in Liver Cancers

, 2014
Yuichi Shiraishi, Akihiro Fujimoto, Mayuko Furuta, Hiroko Tanaka, Kenichi Chiba, Keith A. Boroevich, Tetsuo Abe, Yoshiiku Kawakami, Masaki Ueno, Kunihito Gotoh, Shun‐ichi Ariizumi, Tetsuo Shibuya, Kaoru Nakano, Aya Sasaki, Kazuhiro Maejima, Rina Kitada, Shinya Hayami, Yoshinobu Shigekawa, Shigeru Marubashi, Terumasa Yamada, Michiaki Kubo, Osamu Ishikawa, Hiroshi Aikata, Koji Arihiro, Hideki Ohdan, Masakazu Yamamoto, Hiroki Yamaue, Kazuaki Chayama, Tatsuhiko Tsunoda, Satoru Miyano, Hidewaki Nakagawa   +30 more
openalex   +2 more sources

A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status [PDF]

, 2019
Kurt Wollenberg, Michael A. Harris, Andrei Gabrielian, Nelly Ciobanu, Dumitru Chesov, Alyssa Long, Jessica Taaffe, Darrell E. Hurt, Alex Rosenthal, Michael Tartakovsky, Valeriu Crudu   +10 more
openalex   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source