Results 211 to 220 of about 23,710,291 (301)

Genomic Analysis of Gut Bacteria in Tecia Solanivora: Insights into Host Functions and Their Potential in Biocontrol. [PDF]

Curr Microbiol
Pantoja L, Manotas-Viloria HS, Vanegas J.   +2 more
europepmc   +1 more source

Thirteen-year genomic analysis (2010-2022) reveals high-risk ICU <i>Pseudomonas aeruginosa</i> in China. [PDF]

mLife
Huang J, Chen K, Xie M, Shen W, Ju X, Wu Y, Li J, Zhou H, Huang Y, Zhang Y, Zhang Y, Li T, Xu L, Sun Y, Chen F, Chen S, Deng X, Zhang R, Hu Y.   +18 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Genomic analysis of antibiotic resistance and virulence factors in the uropathogen <i>Citrobacter koseri</i>. [PDF]

Microb Genom
Stephens C, Christenson B, Patacsil E, Velpuri A, Agustin A, Conrad A.   +5 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Integrated Genomic Analysis Uncovers the Evolutionary Landscape and Global Dissemination of Senecavirus A. [PDF]

Vet Sci
Wang W, Zhang S, Zhao Q, Jiang L, Zhu Z, Wen W, Li X.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Integrated chemical and genomic analysis of lipopeptides produced by Bacillus velezensis CMRP4489 with antifungal activity. [PDF]

Sci Rep
Jesus-Nicoletto MLA, Baptista JP, Noriler SA, Gouveia PO, Bertoli AM, Silva DV, Camargo PG, Macedo F, Oliveira JP, Pereira UP, Mello JCP, Novello CR, Rocha U, G de Oliveira A.   +13 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparative Genomic Analysis of Two <i>Phyllanthus emblica</i> Genomes with Endemic and Widespread Cultivar Backgrounds. [PDF]

Life (Basel)
Zheng Y, Wu Q, Zheng Y, Huang J, Wu F.
europepmc   +1 more source