Results 161 to 170 of about 23,710,291 (301)

Genomic analysis of jumbo coliphage fEgEco12. [PDF]

Arch Virol
Badawy S, Skurnik M.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Circulation of fluconazole-resistant Candida auris in Peru confirmed by genomic analysis. [PDF]

Mem Inst Oswaldo Cruz
Paredes-Gago R, Nuñez-Llanos A, Cespedes-Roman C, Izarra-Rojas V, Hurtado V, Padilla-Rojas C, Caceres-Rey O, Lizarraga W.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Comparative genomic analysis and epigenetic profiling of the Drosophila melanogaster B chromosome. [PDF]

Genetics
Ferretti ABSM, Milani D, Martí E, Alves-Gomes RT, Vibranovski MD, Hanlon SL, Cabral-de-Mello DC.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Comparative Genomic Analysis of Tigecycline Resistance Development in Clinical Acinetobacter baumannii Isolates [PDF]

Xiaoxia Li,1,* Junnian Liu,2,* Xinyu Zhang,1 Juan Li,3 Luhan Xuan,1 Sue Yuan,1 Jianglin Li,1 Yu Sun,1 Xuefei Du1 1Clinical Laboratory, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People’s Republic of
Li X, Yuan S, Liu J, Li J, Zhang X, Du X, Sun Y, Xuan L   +7 more
core  

Genomic Analysis of the Columbian Plumage Pattern in Various Chicken Breeds. [PDF]

Animals (Basel)
Azovtseva AI, Ryabova AE, Shcherbakov YS, Larkina TA, Vakhrameev AB, Dementieva NV.   +5 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Genomic Analysis of Hypervirulent <i>Klebsiella pneumoniae</i> ST1-KL122. [PDF]

Iran J Biotechnol
Yang Y, He Z, Dai Y, Lu H, Li Y, Zhang Y, Sun B, Zhou S.   +7 more
europepmc   +1 more source