Results 141 to 150 of about 56,311 (230)

The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3

Plant Biology, Volume 28, Issue 2, Page 328-344, March 2026.
Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz, V. T. Juárez González, R. F. Jiménez‐Ortega, J. L. Reyes, T. D. Dinkova   +4 more
wiley   +1 more source

Editorial: Genomic imprinting and monoallelic gene expression mechanisms and applications. [PDF]

Front Genet, 2022
Oczkowicz M, Tycko B, Demars J.
europepmc   +1 more source

Maternal O‐GlcNAc Transferase Is Required for the Asymmetry of Epigenetic Modifications in Mouse Zygotes

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
OGT inhibition during in vitro oocyte maturation disrupts epigenetic asymmetry in the zygote. It reduces male pronuclear size and eliminates DNA methylation asymmetry by decreasing H3K9me2‐mediated 5mC protection in the female pronucleus and suppressing TET3‐dependent DNA demethylation in the male pronucleus.
Haoxue Wang, Dan Liu, Shinnosuke Honda, Shuntaro Ikeda   +3 more
wiley   +1 more source

Comparative analysis reveals epigenomic evolution related to species traits and genomic imprinting in mammals. [PDF]

Innovation (Camb), 2023
Hu Y, Yuan S, Du X, Liu J, Zhou W, Wei F.   +5 more
europepmc   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Uncovering the phenotypic consequences of multi-locus imprinting disturbances using genome-wide methylation analysis in genomic imprinting disorders. [PDF]

PLoS One, 2023
Kim HY, Shin CH, Shin CH, Ko JM.
europepmc   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, Volume 13, Issue 10, 18 February 2026.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Genomic imprinting-like monoallelic paternal expression determines sex of channel catfish. [PDF]

Sci Adv, 2022
Wang W, Yang Y, Tan S, Zhou T, Liu Y, Tian C, Bao L, Xing, Su B, Wang J, Zhang Y, Liu S, Shi H, Gao D, Dunham R, Liu Z.   +15 more
europepmc   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source