Results 161 to 170 of about 56,311 (230)

Identification of a De Novo MAGEL2 Pathogenic Variant in Schaaf–Yang Syndrome and the Importance of Paternal Allele Confirmation

Journal of Clinical Laboratory Analysis, Volume 40, Issue 3, February 2026.
This study reports a de novo MAGEL2 pathogenic variant in a patient with Schaaf–Yang syndrome, confirmed through methylation‐sensitive analysis. Combining genomic sequencing with methylation assays helps accurately determine the parental origin of MAGEL2 mutations.
Youn‐Ji Hong, Misun Yang, Hyeon Jeong Kwon, Jooyoung Cha, Ja‐Hyun Jang, Sung Eun Wang, Eun Sun Lee, Mi‐Ae Jang   +7 more
wiley   +1 more source

Multi‐Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu, Junsen She, Xinyuan Li, Yishang Yan, Jiaying Mo, Jianzhong Sheng, Hongbo Yang, Hefeng Huang   +7 more
wiley   +1 more source

Balanced gene dosage control rather than parental origin underpins genomic imprinting. [PDF]

Nat Commun, 2022
Weinberg-Shukron A, Ben-Yair R, Takahashi N, Dunjić M, Shtrikman A, Edwards CA, Ferguson-Smith AC, Stelzer Y.   +7 more
europepmc   +1 more source

Microscale Affinity Chromatography for Biointeraction Analysis: Strategies, Principles and Applications

Journal of Separation Science, Volume 49, Issue 2, February 2026.
ABSTRACT The analysis of interactions between biological agents or with surrounding chemicals is important in many areas of modern biochemical, biomedical, and environmental research. Microscale platforms based on affinity chromatography have been shown to be a powerful set of tools for these studies.
David S. Hage, Nigar Sultana Pinky, B. K. Sajeeb, Md Masudur Rahman, Harshana Olupathage, Samiul Alim, Isaac Kyei, Zoe Zingler, Sanduni Heenkenda   +8 more
wiley   +1 more source

Bioinformatics insights into plant genomic imprinting: approaches, challenges, and future perspectives. [PDF]

Brief Funct Genomics
Jing X, Su X, Zou Q, Niu M.
europepmc   +1 more source

Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3. [PDF]

Nat Commun, 2021
Santini L, Halbritter F, Titz-Teixeira F, Suzuki T, Asami M, Ma X, Ramesmayer J, Lackner A, Warr N, Pauler F, Hippenmeyer S, Laue E, Farlik M, Bock C, Beyer A, Perry ACF, Leeb M.   +16 more
europepmc   +1 more source

Effects of Methyl Cycle Substrate Availability on Epigenetic Stability of Human Embryonic Stem Cells [PDF]

A link has been hypothesised to occur between suboptimal maternal nutrition and impaired foetal development leading to a predisposition to a range of adult pathologies.
Barsanti, Marco
core  

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Advances and challenges of precision epigenetic therapy in treating genomic imprinting diseases. [PDF]

Transl Pediatr
Lv Y, Li M, Ji C.
europepmc   +1 more source

A case study on genomic imprinting facilitates student learning.

Adv Physiol Educ, 2023
Goudsouzian LK, Lo SM.
europepmc   +1 more source