Results 171 to 180 of about 56,311 (230)

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Genomic Imprinting, Epigenetic Dysregulation, and Neuropsychiatric Mechanisms in Prader-Willi Syndrome: A Multi-Level Integrative Review. [PDF]

Cells
Śledzikowska Z, Żukow XE, Antos ZM, Waszkiewicz N.   +3 more
europepmc   +1 more source

Genomic Imprinting at the Porcine PLAGL1 Locus and the Orthologous Locus in the Human. [PDF]

Genes (Basel), 2021
Ahn J, Hwang IS, Park MR, Hwang S, Lee K.   +4 more
europepmc   +1 more source

Genome‐wide analysis of somatic noncoding mutation patterns and mitochondrial heteroplasmic shift in type B1 and B2 thymomas

The Journal of Pathology, Volume 268, Issue 2, Page 135-149, February 2026.
Abstract Type B1 and B2 thymomas are lymphocyte‐rich malignant tumours with few somatic mutations in protein‐coding regions of the nuclear genome; nonetheless, noncoding regions remain uncharacterized. Here, we developed a method to isolate pure thymoma cells from lymphocyte‐rich tissues, and then performed genome‐wide deep sequencing. The total number
Kohei Fujikura, Isabel Correa, Susanne Heck, Kaoru Watanabe, Juliet King, Emma McLean, Susan Ndagire, Yoshihisa Takahashi, Masahiko Kuroda, Andrea Bille, Daisuke Nonaka   +10 more
wiley   +1 more source

Environmental Influence on the Untargeted Foliar Metabolome of Naturally Growing Mitragyna Species in Thailand

Plant-Environment Interactions, Volume 7, Issue 1, February 2026.
ABSTRACT This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom). Using untargeted gas chromatography–mass spectrometry (GC–MS), 409 secondary volatile metabolites were annotated across the four species.
Tushar Andriyas, Nisa Leksungnoen, Chatchai Ngernsaengsaruay, Suwimon Uthairatsamee, Rossarin Tansawat, Pakawat Sirilertpanich   +5 more
wiley   +1 more source

Perinatal nutrition as a key regulator of genomic imprinting: a new paradigm for maternal-child health. [PDF]

Front Nutr
Aronica L, Fessler SN, Stone Rydbom E, Jirtle RL.   +3 more
europepmc   +1 more source

Males That Silence Their Father's Genes: Genomic Imprinting of a Complete Haploid Genome. [PDF]

Mol Biol Evol, 2021
de la Filia AG, Mongue AJ, Dorrens J, Lemon H, Laetsch DR, Ross L.   +5 more
europepmc   +1 more source

Multi‐Omics Analysis of Human Blood Cells Reveals Unique Features of Age‐Associated Type 2 CD8 Memory T Cells

Aging Cell, Volume 25, Issue 2, February 2026.
Aging drives the accumulation of CXCR3‐ central memory CD8 T cells that exhibit Th2‐like transcriptional and epigenetic programs. These cells display a pathogenic Th2‐skewed profile and are associated with age‐related diseases, including asthma, chronic liver disease, and type 2 diabetes.
Hiroyuki Matsui, Marlene Cervantes, Mir M. Khalid, Alan Tomusiak, Varun Dwaraka, Jorge Landgrave‐Gomez, Prasanna Vadhana Ashok Kumaar, Qingwen Chen, Jessica Lasky‐Su, Jake Stone, Ritesh Tiwari, Ryan Kwok, Shuntaro Ichikawa, Benjamin D. Ambrose, Rebeccah R. Riley, Genesis Vega Hormazabal, Ariel Adkisson‐Floro, Andreea Cristina Alexandru, Ryan Smith, Birgit Schilling, Herbert G. Kasler, Eric Verdin   +21 more
wiley   +1 more source

Genomic imprinting at a porcine ZNF locus via a canonical imprinting mechanism. [PDF]

Anim Genet
Ahn J, Hwang IS, Park MR, Hwang S, Cho IC, Lee K.   +5 more
europepmc   +1 more source

Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions. [PDF]

Cell Rep, 2022
Bonthuis PJ, Steinwand S, Stacher Hörndli CN, Emery J, Huang WC, Kravitz S, Ferris E, Gregg C.   +7 more
europepmc   +1 more source