Results 71 to 80 of about 1,126,913 (153)

A 12-Gene Genomic Instability Signature Predicts Clinical Outcomes in Multiple Cancer Types

The International Journal of Biological Markers, 2010
Background and aims Genomic instability, as reflected in specific chromosomal aneuploidies and variation in the nuclear DNA content, is a defining feature of human carcinomas.
Rama K.R. Mettu, Ying-Wooi Wan, Jens K. Habermann, Thomas Ried, Nancy Lan Guo   +4 more
doaj   +1 more source

Genomic instability as a prognostic marker in malignant brain cancer [PDF]

, 2023
Introduction: Glioblastoma and Astrocytoma are diff use malignant brain tumors and characterized as the most aggressive and invasive brain cancers. Glioblastoma IDH wild-type is a primary brain tumour that develops de novo, and Astrocytoma IDH mutant is ...
Tanić, Nasta, Rakić, Miodrag, Tanić, Nikola, Ademović, Nejla, Milić, Marina, Tomić, Tijana   +5 more
core  

HBx targets centrosomal protein TAX1BP2 to promote genomic instability

, 2015
Centrosome is a major microtubule-organizing centre for regulating spindle assembly and bipolarity.Evidence suggests that cancer is a multi-step accumulation process of genomic instability resulted from centrosome dysfunction.
Tang, HC, Li, SK, Lau, PY, Zhou, Y, Ching, YP   +4 more
core  

Genomic selection in dairy cattle [PDF]

, 2011
The objectives of this Ph.D. thesis were (1) to optimise genomic selection in dairy cattle with respect to the accuracy of predicting total genetic merit and (2) to optimise a dairy cattle breeding program using genomic selection. The study was performed
de Roos, A.P.W., Roos, A.P.W., de
core  

Advancing prognostic understanding in hepatocellular carcinoma through the integration of genomic instability and lncRNA signatures: GILncSig model

: The recently published study by Duan et al introduces a promising method that combines genomic instability and long non-coding RNAs to improve the prognostic evaluation of hepatocellular carcinoma (HCC), a deadly cancer associated with considerable ...
Zappavigna, Silvia, Caraglia, Michele, Francesca Pentimalli, Bocchetti, Marco, Scrima, Marianna, Marianna Scrima, Pentimalli, Francesca, Misso, Gabriella, Alessia Maria Cossu, Cossu, Alessia Maria, Gabriella Misso, Marco Bocchetti, Silvia Zappavigna, Michele Caraglia   +13 more
core   +1 more source

Using next-generation whole-exome sequencing approaches to elucidate the genetic basis for nasopharyngeal carcinoma

, 2014
Nasopharyngeal carcinoma (NPC) is an intriguing cancer with a high prevalence in Southern Chinese, but is rare in most other parts of the world. In Hong Kong, where this cancer is endemic, NPC is ranked as one of the top cancers in incidence.
Tang, SM, Lung, ML, Ko, JMY, Cheung, AKL, Dai, W, Zheng, H, Sham, PC   +6 more
core  

Genomic Instability Induced By Human Papillomavirus Oncogenes [PDF]

, 2010
Cervical cancer is one of the leading causes of cancer death in women worldwide. Human papillomavirus (HPV) infection is necessary but not sufficient for the development of cervical cancer.
Chen, PhD, Jason J.
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Genomic Instability in Cancer: Teetering on the Limit of Tolerance

, 2017
Cancer genomic instability contributes to the phenomenon of intratumoral genetic heterogeneity, provides the genetic diversity required for natural selection, and enables the extensive phenotypic diversity that is frequently observed among patients ...
Carlo C. Maley, Hanlee P. Ji, Noemi Andor   +2 more
core   +1 more source

A new insight into the impact of copy number variations on cell cycle deregulation of luminal-type breast cancer

Oncology Reviews
Breast cancer is the most prevalent neoplasm in women. ER+ (Luminal subtype), representing over 70% of breast tumors, is a genetically diverse group. Structural and Numerical-Chromosomal instability initiates tumor development and is recognized as the ...
Amir Mahdi Khamaneh, Davoud Jafari-Gharabaghlou, Khalil Ansarin, Khalil Ansarin, Khalil Ansarin, Pouya Pazooki, Zahra Akbarpour, Behrooz Naghili, Behrooz Naghili, Nosratollah Zarghami, Nosratollah Zarghami   +10 more
doaj   +1 more source

Prostate Cancer Cell Line Genomic Instability Scores.

, 2016
Prostate Cancer Cell Line Genomic Instability Scores.
Laura J. Leitz (3350075), Shannon L. Werner (3350087), Shidong Jia (3350105), Eric K. Tucker (3350081), Premal Patel (3350090), Liangxuan Zhang (3350102), Michael Malchiodi (3350093), Yipeng Wang (9800), Stephanie B. Greene (460558), Ryon P. Graf (3350084), Dena Marrinucci (40175), Steven Gendreau (3350078), Angel E. Dago (607604), Ryan Dittamore (3350099), Mark Landers (214385), Jerry Lee (3350096)   +15 more
core   +1 more source