Results 81 to 90 of about 1,126,913 (153)

Method for Detecting or Diagnosing Genomic Instability

, 2009
A method is provided for detecting or diagnosing genomic instability in an individual by determining the difference in mutation frequency between a non-conserved genomic region and an ultra-conserved genomic region (UCR), where a statistically ...
DE GRASSI, ANNA, Ciccarelli F
core  

Mechanisms of c-Myc dependent genomic instability

, 2009
Cancer is a disease that involves genomic instability, to which c-Myc contributes during its initiation and progression. Over 70% of all human cancers show deregulated levels of c-Myc protein.
Louis, Sherif
core  

Ionizing Radiation and Ultraviolet Light Irradiation-Associated DNA Damage Increasing Genomic Instability Risk. [PDF]

Cancer Sci
Yoshioka KI, Matsuno Y, Kusumoto-Matsuo R.   +2 more
europepmc   +1 more source

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review). [PDF]

Oncol Rep
Wang L, Feng Y, Liu Q.
europepmc   +1 more source

Assessment of the Type and Degree of Genomic Instability in Gliomas. [PDF]

Int J Mol Sci
Ademović N, Milić M, Tomić T, Murganić B, Milić I, Tanić N, Tanić N.   +6 more
europepmc   +1 more source

Multiomic profiling links L1 retrotransposition to genomic instability and ecDNA in bladder cancer. [PDF]

Nat Commun
Pribus SJ, Osredek I, Otoničar J, Simovic-Lorenz M, Giovenino C, Rademacher A, Wille SJ, Berzain Battioni C, Scherer M, Manzano-Sanchez S, Kienzle A, Parekh U, Villacorta L, Benes V, Sant P, Mallm JP, Brand K, Rippe K, Riemer AB, Sültmann H, Plass C, Stankovic M, Korbel JO, Rausch T, Ernst A.   +24 more
europepmc   +1 more source

A dual role for cGAS in shaping cellular and organismal responses to genomic instability. [PDF]

Genes Dev
Bergman M, Goshtchevsky U, Atlan T, Astre G, Halabi R, El Ayoubi H, Moses E, Lemus AJJ, Benayoun BA, Tzfati Y, Ben-Ami I, Harel I.   +11 more
europepmc   +1 more source

Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability. [PDF]

Cancers (Basel)
Paparella AT, Boice AG, Park IY, Nishad R, Tripathi D, Nelson SA, Pietryk EW, Jang HJ, Frew IJ, Rathmell WK, Mason FM, Coarfa C, Dere R, Walker CL.   +13 more
europepmc   +1 more source

Editorial: Genomic Instability and Neurodegeneration

Frontiers in Aging Neuroscience, 2022
Julia Fuchs, Bjoern Schwer, Bjoern Schwer, Bjoern Schwer, Bjoern Schwer, Sherif F. El-Khamisy, Sherif F. El-Khamisy   +6 more
doaj   +1 more source

Periostin Safeguards EGFR-Driven Genomic Instability and Sustains the Immune-Suppressive Niche in Glioblastoma. [PDF]

Hum Mutat
Liu H, Tan S, Qi J, Du Z, You J, Muhammad S, Tang X, Li J.   +7 more
europepmc   +1 more source