Results 101 to 110 of about 1,069,336 (306)
A novel approach for mining polymorphic microsatellite markers in silico [PDF]
, 2011 Hoffman J, Nichols HJ. A novel approach for mining polymorphic microsatellite markers in silico. PLoS ONE. 2011;6(8): e23283.Abstract:
An important emerging application of high-throughput 454 sequencing is the isolation of molecular markers such as ...Joseph I. Hoffman, Hoffman, Joseph ; https://orcid.org/, Hazel Nichols, Nichols, H. J., Nichols Hazel J., Hazel J. Nichols, Joseph I Hoffman, Hazel J Nichols, Hoffman Joseph I. +8 morecore +2 more sourcesKDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro +7 morewiley +1 more sourceCross-linking for microbial keratitis
Indian Journal of Ophthalmology, 2013 The success of collagen cross-linking as a clinical modality to modify the clinical course in keratoconus seems to have fueled the search for alternative applications for this treatment.Jayesh Vazirani, Pravin K Vaddavallidoaj +1 more sourceDiatraea saccharalis genomic diversity estimates based on 1,331 SNP loci by sampling locations.
, 2019 Diatraea saccharalis genomic diversity estimates based on 1,331 SNP loci by sampling locations.João Paulo Gomes Viana (4598278), Erick M. G. Cordeiro (7037327), Alessandro Alves-Pereira (138792), Andrea Joyce (4736802), Maria I. Zucchi (663602), Jaqueline B. de Campos (5013416), Gabriela Murua (7037330), Sofia Fogliata (7037333), Xing Wu (328714), Steven J. Clough (203688), Wei Wei (21173), Patrick Brown (198), Fabricio J. B. Francischini (4598287) +12 morecore +1 more sourceGenome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function [PDF]
, 2012 Genome-wide association studies have identified numerous genetic loci for spirometic measures of pulmonary function, forced expiratory volume in one second (FEV1), and its ratio to forced vital capacity (FEV1/FVC).Wenbo Tang (110161), Alisa K. Manning (110227), Heinrich, J (Joachim), Thomas Lumley (57337), Sood, A, R Graham Barr, Brusselle, Guy G., Loth, Daan W, Akshay Sood (71826), O'Connor, George T, Liu, YM, Stephen S. Rich (7634141), Harris, Tamara B, Fornage, Myriam, Alisa K. Manning (7634102), Stephanie J. London (62450), Josée Dupuis (28859), Probst-Hensch, Nicole, Chen, TH, Elliott, Paul, Eiriksdottir, Gudny, Zhai, G., Jason Z. Liu (7634093), Patricia A. Cassano (110298), Hugues Aschard (110171), Joachim Heinrich (60421), Guy G Brusselle, Couper, D. J., Gu, Xiangjun, Uitterlinden, Andre G., Smith, AV, Couper, DJ, Lenore J. Launer (110269), Matthias Wjst (56613), Myriam Fornage (45591), Kritchevsky, S. B., Postma, Dirkje S., Liu, Y, Mirel, D. B., Rurth J.F. Loos (7634099), H. Marike Boezen (7634168), Uitterlinden, André G, Hysi, Pirro G., R. Graham Barr (7634171), Timothy D. Spector (7634159), Glaeser, S, Loos, Ruth J F, Christer Janson, Burkart, Kristin Marie, Heinrich, Joachim, Eiriksdottir, G, Hysi, P., Boezen, H Marike, Zhai, GJ, Liu, Jason, Probst-Hensch, Nicole M, O Dale Williams, George T. O'Connor (110263), Jason Z. Liu (110210), Uitterlinden, AG, Hofman, A., Heckbert, Susan R, David P Strachan, Daan W. Loth (7634072), Louise V. Wain (7588511), Tamara B Harris, Smith, Albert V, Jarvis, Deborah, Imboden, M., Launer, Lenore J, Heckbert, Susan R., Hysi, PG, Morrison, A. C., Marciante, K. D., Rich, Stephen S., Hartikainen, Anna-Liisa, Mirel, Daniel B, Harris, Tamara, Liu, Jason Z, Jarvelin, Marjo-Riitta, Kari E. North (68131), Aldrich, Melinda C., Manning, A. K., Koch, B., Couper, David J., Timothy D Spector, Curjuric, I., Wilk, J. B., Eijgelsheim, Mark, North, Kari E, Louise V Wain, Rivadeneira, F, Williams, O. D., Homuth, G, Marciante, KD, Cassano, P. A., Joanna Smolonska (101730), Susan R. Heckbert (7634165), Strachan, David P., Henry Völzke (64286), Boezen, H. M., Marciante, Kristin D., Jerome I. Rotter (7634114), Ramasamy, A, Alisa K Manning, Lumley, T., Amanda Henry, Daniel B. Mirel (7634153), Mark Eijgelsheim (110185), Bernd Meibohm (110267), Manichaikul, A, Manichaikul, Ani, Amy R Bentley, Daan W Loth, Kristin D. Marciante (110230), Aldrich, Melinda, Zhao, Jing Hua, Hysi, Pirro, Kurt Lohman, Alanna C Morrison, Melinda C. Aldrich (110234), Meibohm, B, O'Connor, George, Imboden, Medea, Gharib, Sina A, Wilk, Jemma B., Gudny Eiriksdottir (8872), Obeidat, Ma’en, Marchini, J, Stricker, Bruno H. C., Kurt Lohman (110218), O. Dale Williams (110242), Stephen B. Kritchevsky (7240181), Alanna C. Morrison (110248), Lenore J Launer, Franceschini, N, Tamara B. Harris (7240184), O’Connor, George T., Probst-Hensch, NM, Maria Soler Artigas (7634069), Launer, Lenore J., Marchini, Jonathan, Dupuis, Josee, Hall, Ian, Loehr, Laura, Nicole M. Probst-Hensch (7634162), Fernando Rivadeneira, Rich, S. S., Sina A. Gharib (63265), Cathy C. Laurie (110245), Kristin D. Marciante (7634105), Hancock, D. B., Stricker, BHC, Tamara B. Harris (110195), Henry, A, Guangju Zhai (110167), Bonnie R. Joubert (110252), Ian P. Hall (7377620), Probst-Hensch, Nicole M., Rotter, Jerome I, Nicholas J Wareham, Vonk, Judith, Dana B. Hancock (110121), R. Graham Barr (109958), Franceschini, Nora, Hammond, Christopher J., Burkart, KM, Bruno H C Stricker, Rochat, Thierry, Rotter, Jerome, Tobin, Martin, Boezen, H. Marike, Loos, Ruth J. F., Artigas, M.S., Loth, Daan W., Josée Dupuis, Medea Imboden, Lohman, K, Hall, I. P., Deborah Jarvis, Wain, Louise V., Guy G. Brusselle (7634108), André G. Uitterlinden (7634138), Loos, RJF, Judith M. Vonk (7634135), George T O'Connor, McArdle, Wendy L., Laurie, Cathy C., Barr, R. Graham, Dupuis, J, Khaw, K. T., Koch, B, Hancock, Dana, Burkart, Kristin, Manning, Alisa K., Tobin, Martin D, Jemma B Wilk, Völzke, H, Paul Elliott, Rochat, T., Artigas, Maria Soler, Boezen, Hendrika, Homuth, G., Patricia A. Cassano (7634174), Stephanie J. London (7634180), Melinda C Aldrich, Gudnason, V, Albert V. Smith (7634078), Bentley, Amy, Pirro G. Hysi (110207), Smith, Albert, Gharib, SA, Rich, Stephen, Albert V Smith, Martin D Tobin, Marjo-Riitta Jarvelin (110290), Dana B. Hancock (7634066), Wareham, N. J., Guy G. Brusselle (110236), Wareham, NJ, Bruce M Psaty, Ani Manichaikul, Smith, Albert V., Anna-Liisa Hartikainen, Nicole M Probst-Hensch, Chen, T-H, Sood, A., Ruth J F Loos, Bentley, Amy R, Gu, X, Jarvelin, MR, Adaikalavan Ramasamy, Daniel B Mirel, Uitterlinden, A., Jing Hua Zhao, Bruno H. C. Stricker (110279), Burkart, Kristen M., Morrison, Alanna, Hall, IP, Psaty, B. M., Meibohm, Bernd, Couper, David, Homuth, Georg, Harris, TB, Heckbert, S. R., Laurie, CC, Chen, T. H., Kritchevsky, Stephen, Mirel, Daniel B., Christopher J Hammond, Akshay Sood, Xiangjun Gu, Daan W. Loth (110140), Wareham, Nicholas J., Obeidat, M, Smolonska, J, Marciante, Kristin, Laurie, C., Psaty, Bruce, Lumley, Thomas, Sven Gläser, André G. Uitterlinden (2213413), Hofman, Albert, Zhao, JH, Jerome I. Rotter (103729), Loehr, Laura R, Yongmei Liu, Myriam Fornage, Cassano, Patricia A, Hartikainen, A. L., Xiangjun Gu (73651), Stricker, Bruno HC, Zhao, J. H., Tang, W, Brusselle, GG, Tang, Wenbo, Voelzke, Henry, Stephen B Kritchevsky, Boezen, Marike, Dana B Hancock, Laurie, Cathy C, London, S. J., Vilmundur Gudnason (8873), Strachan, DP, Jonathan Marchini (21497), Patricia A Cassano, Elliott, P., Susan R. Heckbert (110293), Wjst, M, Martin D. Tobin (110311), Wareham, Nicholas, North, KE, Spector, TD, David J Couper, Chen, Ting-hsu, Rotter, JI, Ramasamy, A., Nicholas J. Wareham (110277), Wain, Louise, Marjo-Riitta Jarvelin, Spector, Timothy D, Ma'en Obeidat, Psaty, Bruce M., Launer, Lenore, Lohman, Kurt, Adaikalavan Ramasamy (4841), Ma'en Obeidat (110232), Hartikainen, A.L., Peter Kraft, Gudnason, V., Dirkje S Postma, Strachan, D. P., Henry Völzke, Tobin, MD, Loehr, L. R., Morrison, Alanna C, Wain, LV, Thierry Rochat, Mcardle, Wendy, Smolonska, Joanna, Stricker, Bruno, Dirkje S. Postma (101740), Manning, AK, Barr, RG, Kraft, Phillip, Vonk, JM, Henry, A., Soler, Artigas, Bentley, A. R., Obeidat, Ma'en, Launer, L. J., Timothy D. Spector (110281), Strachan, David P, Brusselle, Guy, Christopher J. Hammond (110274), Liu, JZ, Loth, D. W., Vonk, Judith M., Wendy L. McArdle (110155), Bernd Meibohm, Loehr, LR, Hammond, Christopher J, Spector, T. D., Marchini, J., Cisca Wijmenga, Vonk, Judith M, Ting-hsu Chen, Ting-Hsu Chen (7634111), Barr, R Graham, Ruth J. F. Loos (110224), Hofman, Bert, Brusselle, G. G., North, Kari, Aschard, H., Kraft, P., Stephen B. Kritchevsky (110259), Bonnie R Joubert, David J. Couper (110257), O'Connor, G. T., Heinrich, J., Ting-hsu Chen (110239), Judith M Vonk, Ramasamy, Adaikalavan, Psaty, Bruce M, Sven Gläser (110276), Nicholas J. Wareham (7584569), Wain, L. V., Boezen, M, Aldrich, MC, Hancock, DB, Heckbert, SR, Hammond, C. J., H Marike Boezen, Christopher J. Hammond (7252211), North, Kari E., Zhai, G, Jing Hua Zhao (73808), Lumley, T, Aldrich, M., Smolonska, J., Vonk, J. M., Khaw, KT, Hartikainen, AL, Lenore J. Launer (7305602), Beate Koch (110151), Stricker, B. H. C., Heckbert, Susan, Kay-Tee Khaw, Williams, O. Dale, Uitterlinden, André, Hancock, Dana B., Ian P. Hall (110307), Kraft, P, Khaw, K-T, Kritchevsky, SB, Nora Franceschini, Jemma B. Wilk (110164), Wareham, Nicholas J, Georg Homuth (110202), Tobin, M. D., Curjuric, Ivan, Amy R. Bentley (110243), Joubert, B. R., Rochat, T, Gharib, Sina, Franceschini, N., Vilmundur Gudnason, Mirel, Daniel, Guangju Zhai, Janson, Christer,, Artigas, MS, Laura R. Loehr (110214), Rivadeneira, Fernando, Rich, SS, Melinda C. Aldrich (6688181), Boezen, HM, Albert V. Smith (103644), Manning, Alisa K, Morrison, Alanna C., Janson, C, Wijmenga, C, Jarvelin, M-R, Bentley, AR, Obeidat, M., David J. Couper (7634132), Mark Eijgelsheim, Kristin M. Burkart (110174), Bentley, Amy R., Jing Hua Zhao (7634084), Kristin M. Burkart (7634087), Loth, DW, Jonathan Marchini, London, SJ, Judith M. Vonk (71591), Kristin D Marciante, Spector, Timothy, Rivandeneiro, Fernando, Ani Manichaikul (110134), Rotter, J. I., Völzke, Henry, Aschard, Hugues, O'Connor, GT, Heinrich, J, Martin D. Tobin (7581161), Fornage, M., Barr, R. G., Bruce M. Psaty (103721), Gu, XJ, Zhai, Guangju, Jarvelin, M. R., Marciante, Kristin D, Ivan Curjuric (110179), Eiriksdottir, G., Susan R Heckbert, Sina A Gharib, Spector, Timothy D., Gläser, Sven, Homuyth, Georg, Medea Imboden (110145), Thomas Lumley, Hysi, Pirro G, Probst-Hensch, N. M., Gu, X., Harris, Tamara B., London, Stephanie J, Henry, Amanda, Joubert, BR, Peter Kraft (15118), Bruce M. Psaty (7634144), Bruno H.C. Stricker (7634156), Jerome I Rotter, Strachan, David, Wjst, M., Cathy C. Laurie (7634123), Meibohm, B., Launer, LJ (Lenore), Gudnason, Vilmundur, Hugues Aschard, Loehr, Laura R., Jarvis, D, Uitterlinden, André; id_orcid, Loth, Daan, Mirel, DB, Khaw, Kay-Tee, Postma, Dirkje S, Hall, Ian P, Rivadeneira, F., Deborah Jarvis (59834), Liu, Yongmei, Nicole M. Probst-Hensch (110284), Wilk, JB, Ivan Curjuric, Karl E. North (7634150), Curjuric, I, Liu, Jason Z., Kristin M Burkart, David P. Strachan (7634177), Burkart, Kristin M, Soler Artigas, María, Joanna Smolonska, Williams, O Dale, Kraft, Peter, Gläser, S, Pirro G. Hysi (7634090), Liu, J. Z., Eijgelsheim, M., Morrison, AC, Smith, A. V., Kay-Tee Khaw (110271), Wijmenga, Cisca, Albert Hofman, Elliott, P, Wendy L. McArdle (7634075), London, Stephanie J., Fornage, M, Gharib, Sina A., André G Uitterlinden, Voelzke, H, Loos, R., María Soler Artigas (110124), Hammond, CJ, Postma, Dirkje, Joubert, Bonnie, O'Connor, George T., Laurie, Cathy, Chen, T.H., McArdle, Wendy L, Kritchevsky, Stephen B, Glaeser, Sven, Loos, RJ, Alanna C. Morrison (7634126), Aldrich, Melinda C, Brusselle, Guy G, Cisca Wijmenga (32954), Joubert, Bonnie R., Imboden, M, Jemma B. Wilk (7634081), Jarvis, D., Rich, Stephen S, Ian P Hall, Christer Janson (83414), Sood, Akshay, McArdle, WL, Harris, T. B., Hammond, Christopher, Amanda Henry (110129), Kari E North, Couper, David J, Psaty, BM, Wenbo Tang, London, Stephanie, McArdle, W., Cathy C Laurie, Hartikainen, A-L, Louise V. Wain (110260), Wjst, Matthias, Hancock, Dana B, Bonnie R. Joubert (7634129), Janson, C., Koch, Beate, David P. Strachan (110302), Loos, Ruth, Wijmenga, C., Cassano, PA, Pirro G Hysi, Joubert, Bonnie R, Stricker, Bruno H C, Stephanie J London, Eijgelsheim, M, Georg Homuth, H. Marike Boezen (101746), Dupuis, J., Manning, Alisa, Tang, W., Kritchevsky, Stephen B., George T. O'Connor (7634147), Manichaikul, A., Laura R Loehr, Amy R. Bentley (7634120), Hofman, A, Postma, D., Stephen S. Rich (110262), Albert Hofman (107303), Wijmenga, Cisca; id_orcid, Matthias Wjst, Stricker, BH, Gharib, S. A., Wilk, Jemma, Burkart, Kristin M., Burkart, K. M., Beate Koch, Launer, LJ, O. Dale Williams (7634117), Cassano, Patricia A., Daniel B. Mirel (110265), Joachim Heinrich, Tang, WB, Janson, Christer, Postma, DS, Stephen S Rich, North, K. E., Thierry Rochat (110261), Paul Elliott (27295), Laura R. Loehr (7634096), Hall, Ian P., Nora Franceschini (91434), Tobin, Martin D., Aschard, H, Wain, Louise V, Liu, Y., Rotter, Jerome I., Wendy L McArdle, Lohman, K., Gudny Eiriksdottir, Williams, OD, Jason Z Liu, Anna-Liisa Hartikainen (110272), Wilk, Jemma B, María Soler Artigas, Yongmei Liu (104713), Cassano, Patricia, Fernando Rivadeneira (61551), Loos, Ruth JF, London, S.J. (Stephanie), Rivadeneira Ramirez, F. (Fernando), Morrison, A.C. (Alanna), Heinrich, J. (Joachim), Bentley, A.R. (Amy), Cassano, P.A. (Patricia), Hall, I.P. (Ian), Smolonska, J. (Joanna), Rich, S.S. (Stephen), Harris, T.B. (Tamara), Khaw, K-T. (Kay-Tee), Tobin, M.D. (Martin), O'Connor, G.T. (George), Janson, C. (Christer), Franceschini, N. (Nora), Laurie, C.C. (Cathy), Loehr, L.R. (Laura), Homuth, G. (Georg), Völzke, H. (Henry), Hancock, D.B. (Dana), Gläser, S. (Sven), Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Joubert, B.R. (Bonnie), Imboden, M. (Medea), Gudnason, V. (Vilmundur), Gharib, S.A. (Sina), Williams, O.D. (Dale), Uitterlinden, A.G. (André), Sood, A. (Akshay), Manichaikul, A. (Ani), Burkart, K.M. (Kristin), Wain, L.V. (Louise), Hammond, C.J. (Christopher), Brusselle, G.G. (Guy), McArdle, W.L. (Wendy), Psaty, B.M. (Bruce), Vonk, J.M. (Judith), Curjuric, I. (Ivan), Smith, A.V. (Davey), Marchini, J. (Jonathan), Aschard, H. (Hugues), Strachan, D.P. (David), Manning, A.K. (Alisa), Jarvis, D.L. (Deborah), Boezen, H.M. (Marike), Marciante, K. (Kristin), Dupuis, J. (Josée), Wjst, M. (Matthias), Zhai, G. (Guangju), Liu, Y. (YongMei), Rotter, J.I. (Jerome), Probst-Hensch, N.M. (Nicole M.), Rochat, T. (Thierry), Koch, B. (Beate), Heckbert, S.R. (Susan), North, K.E. (Kari), Wijmenga, C. (Cisca), Elliott, P. (Paul), Aldrich, M.C. (Melinda), Loth, D.W. (Daan), Stricker, B.H.Ch. (Bruno), Eiriksdottir, G. (Gudny), Jarvelin, M.-R. (Marjo-Riitta), Wilk, J.B. (Jemma), Tang, W. (Wenbo), Ramasamy, A. (Adaikalavan), Lohman, K. (Kurt), Mirel, D. (Daniel), Hysi, P.G. (Pirro), Spector, T.D. (Timothy), Henry, A. (Amanda), Hofman, A. (Albert), Kraft, P. (Peter), Zhao, J.H. (Jing Hua), Eijgelsheim, M. (Mark), Fornage, M. (Myriam), Liu, J. (Jason), Couper, D.J. (David), Gu, X. (Xiangjun), Lumley, T. (Thomas), Launer, L.J. (Lenore), Postma, D.S. (Dirkje), Barr, R.G. (Graham), Kritchevsky, S.B. (Stephen), Obeidat, M. (Ma'en), Meibohm, B. (Bernd), O'Connor, GT, Gläser, S., Völzke, H. +712 morecore +1 more sourceEvolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna +6 morewiley +1 more sourceImaging modalities in keratoconus
Indian Journal of Ophthalmology, 2013 Diagnosis of keratoconus has greatly improved from simple clinical diagnosis with the advent of better diagnostic devices like corneal topographers based on placido disc, elevation based topographers and lately optical coherence tomography (OCT).Himanshu Matalia, Rishi Swarupdoaj +1 more sourceDruggability of Coronary Artery Disease Risk Loci [PDF]
, 2018 BACKGROUND: Genome-wide association studies have identified multiple loci associated with coronary artery disease and myocardial infarction, but only a few of these loci are current targets for on-market medications.Asselbergs, Folkert W, Tragante, Vinicius, Hemerich, D, Erdmann, J, Lempiäinen, Harri, Patel, Riyaz S, Braenne, I, Moore, JH, Alshabeeb, Mohammad, Tragante, V, Schunkert, Heribert, Brænne, Ingrid, Moore, Jason H, Hemerich, Daiane, den Ruijter, Hester M, Schunkert, H, Lempiaeinen, H, Barnes, MR, Alshabeeb, M, Asselbergs, FW, Patel, RS, Erdmann, Jeanette, Barnes, Michael R, den Ruijter, HM, Onderzoek Precision medicine, Experimentele Afd. Cardiologie 1, Team Medisch, Circulatory Health +27 morecore +1 more sourceDual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello +7 morewiley +1 more source
