Results 1 to 10 of about 536,771 (324)

Genome position specific priors for genomic prediction [PDF]

open access: yesBMC Genomics, 2012
Background The accuracy of genomic prediction is highly dependent on the size of the reference population. For small populations, including information from other populations could improve this accuracy.
Brøndum Rasmus   +5 more
doaj   +5 more sources

Protein structure prediction in genomics [PDF]

open access: bronzeBriefings in Bioinformatics, 2001
As the number of completely sequenced genomes rapidly increases, including now the complete Human Genome sequence, the post-genomic problems of genome-scale protein structure determination and the issue of gene function identification become ever more pressing.
David T. Jones
openalex   +3 more sources

Accurate Genomic Prediction Of Human Height [PDF]

open access: yesGenetics, 2017
We construct genomic predictors for heritable and extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning).
Avery, Steven G.   +5 more
core   +5 more sources

Prediction of inherited genomic susceptibility to 20 common cancer types by a supervised machine-learning method. [PDF]

open access: bronze, 2018
Prevention and early intervention are the most effective ways of avoiding or minimizing psychological, physical, and financial suffering from cancer. However, such proactive action requires the ability to predict the individual's susceptibility to cancer
Kim, Byung-Ju, Kim, Sung-Hou
core   +4 more sources

Predicting the accuracy of genomic predictions [PDF]

open access: yesGenetics Selection Evolution, 2021
Abstract Background Mathematical models are needed for the design of breeding programs using genomic prediction. While deterministic models for selection on pedigree-based estimates of breeding values (PEBV) are available, these have not been fully developed for genomic selection, with a key missing component being the ...
Dekkers, Jack C. M.   +2 more
openaire   +4 more sources

Genomic Prediction for Twin Pregnancies [PDF]

open access: yesAnimals, 2021
Twinning is a multifactorial trait influenced by both genetic and environmental factors that can negatively impact animal welfare and economic sustainability on commercial dairy operations. To date, using genetic selection as a tool for reducing twinning rates on commercial dairies has been proposed, but not yet implemented.
Shaileen P. McGovern   +6 more
openaire   +3 more sources

Sibling variation in polygenic traits and DNA recombination mapping with UK Biobank and IVF family data

open access: yesScientific Reports, 2023
We use UK Biobank and a unique IVF family dataset (including genotyped embryos) to investigate sibling variation in both phenotype and genotype. We compare phenotype (disease status, height, blood biomarkers) and genotype (polygenic scores, polygenic ...
Louis Lello   +3 more
doaj   +1 more source

Estimation of Pool Construction and Technical Error

open access: yesAgriculture, 2021
Pooling animals with extreme phenotypes can improve the accuracy of genetic evaluation or provide genetic evaluation for novel traits at relatively low cost by exploiting large amounts of low-cost phenotypic data from animals in the commercial sector ...
John Keele   +4 more
doaj   +1 more source

Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages [PDF]

open access: yes, 2020
Open Access Article; Published online: 11 Dec 2019Assembly of a training population (TP) is an important component of effective genomic selection‐based breeding programs.
Egesi, C.   +11 more
core   +1 more source

Home - About - Disclaimer - Privacy