Results 21 to 30 of about 301,899 (294)

Pan-genomic open reading frames: A potential supplement of single nucleotide polymorphisms in estimation of heritability and genomic prediction.

PLoS Genetics, 2020
Pan-genomic open reading frames (ORFs) potentially carry protein-coding gene or coding variant information in a population. In this study, we suggest that pan-genomic ORFs are promising to be utilized in estimation of heritability and genomic prediction.
Zhengcao Li, Henner Simianer
doaj   +1 more source

Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits

G3: Genes, Genomes, Genetics, 2020
Due to the ever-increasing data collected in genomic breeding programs, there is a need for genomic prediction models that can deal better with big data.
Abelardo Montesinos-López, Humberto Gutierrez-Pulido, Osval Antonio Montesinos-López, José Crossa   +3 more
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Enhancing Genome-Enabled Prediction by Bagging Genomic BLUP

PLoS ONE, 2014
We examined whether or not the predictive ability of genomic best linear unbiased prediction (GBLUP) could be improved via a resampling method used in machine learning: bootstrap aggregating sampling ("bagging"). In theory, bagging can be useful when the predictor has large variance or when the number of markers is much larger than sample size ...
Gianola D, Weigel KA, Kramer N, Stella A, Schon CC   +4 more
openaire   +4 more sources

Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer

Scientific Reports, 2019
We construct risk predictors using polygenic scores (PGS) computed from common Single Nucleotide Polymorphisms (SNPs) for a number of complex disease conditions, using L1-penalized regression (also known as LASSO) on case-control data from UK Biobank ...
Louis Lello, Timothy G. Raben, Soke Yuen Yong, Laurent C. A. M. Tellier, Stephen D. H. Hsu   +4 more
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Haplotype analysis of genomic prediction by incorporating genomic pathway information based on high-density SNP marker in Chinese yellow-feathered chicken

Poultry Science, 2023
: Genomic selection using single nucleotide polymorphism (SNP) markers is now intensively investigated in breeding and has been widely utilized for genetic improvement.
Haoqiang Ye, Zhenqiang Xu, Semiu Folaniyi Bello, Qianghui Zhu, Shaofen Kong, Ming Zheng, Xiang Fang, Xinzheng Jia, Haiping Xu, Xiquan Zhang, Qinghua Nie   +10 more
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Accurate Genomic Prediction of Human Height [PDF]

Genetics, 2017
Abstract Hsu et al. used advanced methods from machine learning to analyze almost half a million genomes. They produced, for the first time, accurate genomic predictors for complex traits such as height, bone density, and educational attainment...
Lello, Louis, Avery, Steven G., Tellier, Laurent, Vazquez, Ana I., de los Campos, Gustavo, Hsu, Stephen D. H.   +5 more
openaire   +4 more sources

A classic approach for determining genomic prediction accuracy under terminal drought stress and well-watered conditions in wheat landraces and cultivars.

PLoS ONE, 2021
The present study aimed to improve the accuracy of genomic prediction of 16 agronomic traits in a diverse bread wheat (Triticum aestivum L.) germplasm under terminal drought stress and well-watered conditions in semi-arid environments.
Morteza Shabannejad, Mohammad-Reza Bihamta, Eslam Majidi-Hervan, Hadi Alipour, Asa Ebrahimi   +4 more
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Preselecting Variants from Large-Scale Genome-Wide Association Study Meta-Analyses Increases the Genomic Prediction Accuracy of Growth and Carcass Traits in Large White Pigs

Animals, 2023
Preselected variants associated with the trait of interest from genome-wide association studies (GWASs) are available to improve genomic prediction in pigs.
Chen Wei, Chengjie Chang, Wenjing Zhang, Duanyang Ren, Xiaodian Cai, Tianru Zhou, Shaolei Shi, Xibo Wu, Jinglei Si, Xiaolong Yuan, Jiaqi Li, Zhe Zhang   +11 more
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Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds

BMC Genomics, 2017
Background A better understanding of the genetic architecture underlying complex traits (e.g., the distribution of causal variants and their effects) may aid in the genomic prediction.
Lingzhao Fang, Goutam Sahana, Peipei Ma, Guosheng Su, Ying Yu, Shengli Zhang, Mogens Sandø Lund, Peter Sørensen   +7 more
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Multi-Trait Multi-Environment Genomic Prediction of Agronomic Traits in Advanced Breeding Lines of Winter Wheat

Frontiers in Plant Science, 2021
Genomic prediction is a promising approach for accelerating the genetic gain of complex traits in wheat breeding. However, increasing the prediction accuracy (PA) of genomic prediction (GP) models remains a challenge in the successful implementation of ...
Harsimardeep S. Gill, Jyotirmoy Halder, Jinfeng Zhang, Navreet K. Brar, Teerath S. Rai, Cody Hall, Amy Bernardo, Paul St Amand, Guihua Bai, Eric Olson, Shaukat Ali, Brent Turnipseed, Sunish K. Sehgal   +12 more
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