Results 91 to 100 of about 2,697,056 (259)

The impact of epistatic selection on the genomic traces of selection [PDF]

Molecular Ecology, 2009
The rapid accumulation of genomic data has led to an explosion of studies searching for signals of past selection left within DNA sequences. Yet the majority of theoretical studies investigating the traces of selection have assumed a simple form of selection, without interactions among selectively fixed sites.
Sarah P, Otto, Michael C, Whitlock
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Weighted GBLUP in Simulated Beef Cattle Populations: Impact of Reference Population, Marker Density, and Heritability

Animals
Genomic selection (GS) is a technique that integrates genomic data, pedigree information, and individual phenotypes to enhance genetic improvements of economically important traits in livestock. While it has shown significant effects in dairy cattle, its
Le Zhou, Lin Zhu, Chencheng Chang, Fengying Ma, Zaixia Liu, Mingjuan Gu, Risu Na, Wenguang Zhang   +7 more
doaj   +1 more source

The founding charter of the Genomic Observatories Network [PDF]

, 2014
The co-authors of this paper hereby state their intention to work together to launch the Genomic Observatories Network (GOs Network) for which this document will serve as its Founding Charter.
Leong, Jo Ann, Clark, M., Gloeckner, Frank Oliver, Gerdts, G., Coddington, Jonathan, Yuri P Springer, Naiara Rodriguez-Ezpeleta, Springer, Yuri P., Karsten Schonrogge, Bietz, Matthew J, Angel Borja, Marteinsson, Viggo Thor, Penny R Hirsch, Clark, M. S., Scholin, C., Wooley, J. C., Wooley, J., Meyer, C., Tetsukazu Yahara, Scholan, Chris, Patricia Wecker, Nathalie Simon, Hanson, Paul C., Koo, M. S., D. Myrold, David, Gates, R. D., null null, GOs-COS, Leong, J-A., Amaral-Zettler, L., Jean-Marc Hero, Meyer, Folker, Antje Wichels, Fuhrman, J., Jonathan Coddington, Scholin, Chris, Drummond, Alexei, Marteinsson, Viggó, Gerdts, Gunnar, Hero, J., Glöckner, Frank, Simon, Nathalie, Kotoulas, Gergios, Paul C Hanson, Vogler, Alfried P., Stone, G., Stones-Havas, Steve, Knight, R., Levente Bodrossy, Hirsch, Penny R., Véronique Berteaux-Lecellier, Vogler, A., Deck, J., Linda Amaral-Zettler, Field, D., Geller, J., Neil Davies, Alfried P Vogler, Schonrogge, K., Lowe, Andrew J., Wooley, John C., Polymenakou, P., Steve Stones-Havas, John C Wooley, Zingone, Adriana, co-authors, 6 7, Barbier, M., Morrison, N., Ratnasingham, Sujeevan, Field, Dawn, Bertilsson, S., Vogler, Alfried P, Barbier, Michèle, Wichels, Antje, Kate M Thibault, Gillespie, Rosemary, Marteinsson, V., Hanson, P., Bodrossy, Levente, Drummond, A., Valette-Silver, Nathalie J, Serge Planes, Ratnasingham, S., Barker, K., ?, ?, Bertilsson, Stefan, Stone, Graham N., Anna Klindworth, Jeanthon, C., Sansone, S., Springer, Y. P., Planes, Serge, Parnell, J., Chris Meyer, Hanson, P. C., Matthias Obst, Michelle S Koo, Jeanthon, Christian, Alexei Drummond, Leong, Jo-Ann, Glockner, F. O., Jansson, Janet, Myrold, David D., Jansson, Janet, K., Stone, Graham N, Sansone, Susanna-Assunta, Lowe, A., Parnell, John, Glöckner, F., Obst, M., Thibault, K. M., Barker, Katherine, Kao, R., Marteinsson, V. T., Hirsch, Penny, Thibault, Kate M., Koo, M., Davies, Neil, Sujeevan Ratnasingham, Hirsch, P., Rosemary Gillespie, Wecker, Patricia, Polymenakou, Paraskevi N, Gilbert, J., Vogler, A. P., Simon, N., Myrold, D., Faith, D., Koo, Michelle S, Gates, Ruth D., Paraskevi N Polymenakou, Andrew J Lowe, Yahara, T., Kelly Goodwin, Clark, Melody S, Jack Gilbert, Parker, Stefanie, Rodriguez- Ezpeleta, Naiara, Rodriguez-Ezpeleta, Naiara, Borja, A., Hirsch, Penny R, Clark, Melody S., Knight, Rob, George K Roderick, Yahara, Tetsukazu, Norman Morrison, Roderick, George K, John Deck, David Hoekman, Faith, Daniel P, Stephanie Parker, Gates, R., Hanson, Paul C, Fuhrman, Jed, Toonen, R., Berteaux-Lecellier, Véronique, Parnell, Jacob J., Wichels, A., Drummond, Alexei J., Meyer, Chris, Rebecca Kao, Kottmann, Renzo, Goodwin, K., Zingone, A., Wecker, P., Jason Bobe, Bobe, Jason, Gunnar Gerdts, Planes, S., Leong, J., Jansson, J., John Jacob Parnell, Hero, Jean-Marc, Katherine Barker, Roderick, G. K., Graham N Stone, Hero, J-M., Jed Fuhrman, Susanna-Assunta Sansone, Bietz, M., Pafilis, Evangelos, Renzo Kottmann, Morrison, Norman, Wooley, John C, Parker, Stephanie, Dawn Field, Deck, John, Roderick, G., Springer, Yuri P, Rob Toonen, Matthew J Bietz, Myrold, D. D., Parker, S., Berteaux-Lecellier, V., Hoekman, David, Valette-Silver, N., Ruth D Gates, Bicak, M., Hoekman, D., Geller, Jonathan, Christian Jeanthon, Polymenakou, P. N., Sansone, S-A., Lowe, Andrew J, Kotoulas, Georgios, Amaral-Zettler, Linda, Glöckner, Frank Oliver, Springer, Y., Georgios Kotoulas, Janet Jansson, Folker Meyer, Borja, Angel, Faith, Daniel P., Kottmann, R., Schonrogge, Karsten, Springer, Yuri, Obst, Matthias, Michèle Barbier, Nathalie J Valette-Silver, Bietz, Matthew J., Roderick, George K., Bietz, M. J., Goodwin, Kelly, Stefan Bertilsson, Gillespie, R., Valette-Silver, N. J., Polymenakou, Paraskevi N., Parnell, J. J., Bobe, J., Meyer, F., Jonathan Geller, Davies, N., Stone, G. N., Bicak, Mesude, Frank Oliver Glöckner, David D Myrold, Coddington, J., Gilbert, Jack, Chris Scholin, Rodriguez-Ezpeleta, N., Myrold, David D, Thibault, Kate M, Melody S Clark, Gos-Cos, Gos-Cos, Stones-Havas, S., Evangelos Pafilis, Gates, Ruth D, Klindworth, Anna, Klindworth, A., Jo-Ann Leong, Pafilis, E., Kotoulas, G., Hirsch, P. R., Koo, Michelle S., Viggó Thór Marteinsson, Mesude Bicak, Jansson, Janet,, Faith, D. P., Adriana Zingone, Rob Knight, Bodrossy, L., Thibault, K., Daniel P Faith, Toonen, Rob, Valette-Silver, Nathalie J., Kao, Rebecca, Parnell, John Jacob   +266 more
core   +2 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Multivariate Genomic Selection and Potential of Rapid Indirect Selection with Speed Breeding in Spring Wheat [PDF]

, 2019
Genomic selection (GS) can be effective in breeding for quantitative traits, such as yield, by reducing the selection cycle duration. Speed breeding (SB) uses extended photoperiod and temperature control to enable rapid generation advancement.
Jesse Poland, Christopher, J., Rutkoski, Jessica, Rutkoski, J., Christopher, Jack, Lee T. Hickey, Poland, J., Jack Christopher, Watson, Amy, Watson, A., Hayes, Ben J., Hayes, B. J., Poland, Jesse, Amy Watson, Jessica Rutkoski, Hickey, Lee T., Hickey, L. T., Ben J. Hayes   +17 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Optimising desired gain indices to maximise selection response

Frontiers in Plant Science
IntroductionIn plant breeding, we often aim to improve multiple traits at once. However, without knowing the economic value of each trait, it is hard to decide which traits to focus on.
Reem Joukhadar, Yongjun Li, Rebecca Thistlethwaite, Kerrie L. Forrest, Josquin F. Tibbits, Richard Trethowan, Richard Trethowan, Matthew J. Hayden, Matthew J. Hayden   +8 more
doaj   +1 more source

Genomic Selective Constraints in Murid Noncoding DNA [PDF]

, 2006
Recent work has suggested that there are many more selectively constrained, functional noncoding than coding sites in mammalian genomes. However, little is known about how selective constraint varies amongst different classes of noncoding DNA.
Peter D Keightley, Daniel J Gaffney, Gaffney Daniel J, Keightley, Peter, Keightley Peter D, Gaffney, Daniel   +5 more
core   +2 more sources