Results 81 to 90 of about 616,505 (302)

Anti-Inflammatory Effect of Deep-Sea Mineral Water on LPS-Induced Inflammation in Raw 264.7 Murine Macrophage Cells and Zebrafish Larvae

Immuno
Deep-sea mineral water (DSW) consists of different compositions and properties. The composition can be varied in different seas all around the world.
Hitihami M. S. M. Wijerathna, Bulumulle P. M. Vileka Jayamali, Deok-Soo Moon, Choong-Gon Kim, Sumi Jung, Jehee Lee   +5 more
doaj   +1 more source

Efficient Breeding by Genomic Mating

Frontiers in Genetics, 2016
Selection in breeding programs can be done by using phenotypes (phenotypic selection), pedigree relationship (breeding value selection) or molecular markers (marker assisted selection or genomic selection).
Deniz Akdemir, Julio Isidro Sanchez
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

ICGRM: integrative construction of genomic relationship matrix combining multiple genomic regions for big dataset

BMC Bioinformatics, 2019
Background Genomic prediction is an advanced method for estimating genetic values, which has been widely accepted for genetic evaluation in animal and disease-risk prediction in human. It estimates genetic values with genome-wide distributed SNPs instead
Dan Jiang, Cong Xin, Jinhua Ye, Yingbo Yuan, Ming Fang   +4 more
doaj   +1 more source

A Ranking Approach to Genomic Selection

PLOS ONE, 2015
Genomic selection (GS) is a recent selective breeding method which uses predictive models based on whole-genome molecular markers. Until now, existing studies formulated GS as the problem of modeling an individual's breeding value for a particular trait of interest, i.e., as a regression problem.
Mathieu Blondel, Akio Onogi, Hiroyoshi Iwata, Naonori Ueda   +3 more
openaire   +4 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Optimising the analysis of transcript data using high density oligonucleotide arrays and genomic DNA-based probe selection [PDF]

, 2007
Background: Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal intensities across probe-pairs within
Sean T May, Martin R Broadley, John P Hammond, Graham Neil S, Neil S Graham, Philip J White, Broadley Martin R, Graham, Neil S., White, Philip J., Hammond John P, White Philip J, May Sean T, Broadley, Martin R., Hammond, John P., May, Sean T.   +14 more
core   +1 more source

Genomic prediction of survival traits for scuticociliatosis resistance in a vaccinated olive flounder cohort: Comprehensive evaluation and optimization of statistical and machine learning models

Aquaculture Reports
Genomic prediction utilizes genome-wide markers to facilitate genomic selection in aquaculture, enabling more precise and accelerated genetic gains compared to traditional pedigree-based methods.
Yasara Kavindi Kodagoda, Gaeun Kim, D.S. Liyanage, W.K.M. Omeka, Cheonguk Park, Jeongeun Kim, H.A.C.R. Hanchapola, M.A.H. Dilshan, D.C.G. Rodrigo, G.A.N.P. Ganepola, David B. Jones, Cecile Massault, Dean R. Jerry, Jihun Lee, Jehee Lee   +14 more
doaj   +1 more source

Turning science on robust cattle into improved genetic selection decisions

Animal, 2012
More robust cattle have the potential to increase farm profitability, improve animal welfare, reduce the contribution of ruminant livestock to greenhouse gas emissions and decrease the risk of food shortages in the face of increased variability in the ...
P.R. Amer
doaj   +1 more source